| Literature DB >> 33625570 |
Anca Butiuc-Keul1,2, Rahela Carpa1,2, Dorina Podar1,2, Edina Szekeres3, Vasile Muntean1,2, Dumitrana Iordache1,2, Anca Farkas4,5.
Abstract
Selection and dissemination of resistant bacteria and antibiotic resistance genes (ARGs) require a deeper understanding since antibiotics are permanently released to the environment. The objective of this paper was to evaluate the phenotypic resistance of 499 isolates of Pseudomonas spp. from urban water sources, and the prevalence of 20 ARGs within those isolates. Resistance to penicillins, cephalosporins, carbapenems, quinolones, macrolides, and tetracyclines was mainly observed in the hospital effluent, municipal wastewater and river water downstream the city. Resistant strains were frequently identified as P. aeruginosa and P. putida. P. aeruginosa isolates were mostly resistant to cefepime, ceftazidime, imipenem, and gentamycin, while P. putida strains were especially resistant to piperacillin-tazobactam. ARGs such as blaTEM-1, blaSHV-1, blaPER-1, blaAmpC, blaVIM-1, PstS, qnrA, qnrB, ermB, tetA, tetB and tetC have been detected. The blaAmpC gene was found in P. aeruginosa, while blaTEM-1 and blaPER-1 genes were found in P. putida. Class 1 integron integrase gene was found in 6.81% of the Pseudomonas isolates.Entities:
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Year: 2021 PMID： 33625570 DOI： 10.1007/s00284-021-02389-w
Source DB: PubMed Journal: Curr Microbiol ISSN： 0343-8651 Impact factor: 2.188