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Literature DB >> 3360446

Chromosome abnormalities in peripheral blood lymphocytes from untreated Hodgkin's patients. A possible evidence for chromosome instability.

L Barrios¹, M R Caballín, R Mirò, C Fuster, G Berrozpe, A Subías, X Batlle, J Egozcue.

Abstract

We describe the presence of a high frequency of spontaneous chromosome aberrations in lymphocytes from six untreated patients with Hodgkin's disease. The characteristics of the chromosome abnormalities observed suggest the existence of a certain degree of chromosome instability in these cases, that could be a predisposing factor for the development of malignancies.

Entities: Disease Species

Mesh：

Year: 1988 PMID： 3360446 DOI： 10.1007/bf00291727

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

29 in total

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Authors: J E Maldonado; H F Taswell; J M Kiely
Journal: Lancet Date: 1972-12-09 Impact factor: 79.321

2. Cytogenetic findings in nodular paragranuloma (Hodgkin's disease with lymphocytic predominance; nodular) and in progressively transformed germinal centers.

Authors: M L Hansmann; E Gödde-Salz; P K Hui; H K Müller-Hermelink; K Lennert
Journal: Cancer Genet Cytogenet Date: 1986-04-15

3. Chromosome instability in patients with medullary carcinoma of the thyroid.

Authors: T C Hsu; S Pathak; N Samaan; R C Hickey
Journal: JAMA Date: 1981-11-06 Impact factor: 56.272

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Authors: K Kurvink; C D Bloomfield; K M Keenan; S Levitt; J Cervenka
Journal: Hum Genet Date: 1978-10-31 Impact factor: 4.132

5. Indirect stimulation of B-cell proliferation in vitro by T cells, as evidenced by cytogenetic analysis of PHA-stimulated cell cultures of B-cell lymphomas.

Authors: K Vermaelen; D Barbieri; H Van den Berghe
Journal: Cancer Genet Cytogenet Date: 1984-04

6. Chromosome fragility in patients with sporadic unilateral retinoblastoma.

Authors: M de Nuñez; V B Penchaszadeh; E Pimentel
Journal: Cancer Genet Cytogenet Date: 1984-02

7. The chromosome changes in non-Burkitt lymphomas.

Authors: B R Reeves; V L Pickup
Journal: Hum Genet Date: 1980 Impact factor: 4.132

8. Cytogenetic and cytokinetic analysis of lymphocytes from patients with hereditary adenomatosis of the colon and rectum.

Authors: T Kasukawa; T Watanabe; A Endo
Journal: Cancer Genet Cytogenet Date: 1985-03-01

9. Familial fragile site found at the cancer breakpoint (1)(q32). Inducibility by distamycin A, concomitance with fragile (16)(q22).

Authors: F Shabtai; J Hart; D Klar; I Halbrecht
Journal: Hum Genet Date: 1986-07 Impact factor: 4.132

10. Chromosomal aberrations and cancer risk.

Authors: I Nordenson; L Beckman; S Lidén; N Stjernberg
Journal: Hum Hered Date: 1984 Impact factor: 0.444

13 in total

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Authors: E van den Berg-de Ruiter; B de Jong; N H Mulder; G J te Meerman; H Schraffordt Koops; D T Sleijfer
Journal: Hum Genet Date: 1990-01 Impact factor: 4.132

2. Chromosomal damage in lymphocytes and fibroblasts of patients treated for testicular cancer.

Authors: C D DeLozier-Blanchet
Journal: Hum Genet Date: 1990-10 Impact factor: 4.132

3. The kelch protein KLHDC8B guards against mitotic errors, centrosomal amplification, and chromosomal instability.

Authors: Maxwell M Krem; Ping Luo; Brandon I Ing; Marshall S Horwitz
Journal: J Biol Chem Date: 2012-09-17 Impact factor: 5.157

Review 4. Relationship between Hodgkin's and non-Hodgkin's lymphomas.

Authors: Rose-Marie Amini; Gunilla Enblad
Journal: Med Oncol Date: 2003 Impact factor: 3.064

Review 5. The biology of Hodgkin's lymphoma.

Authors: Ralf Küppers
Journal: Nat Rev Cancer Date: 2008-12-11 Impact factor: 60.716

6. Chromosomal instability in breast cancer patients.

Authors: L Barrios; M R Caballín; R Miró; C Fuster; F Guedea; A Subias; J Egozcue
Journal: Hum Genet Date: 1991-11 Impact factor: 4.132

7. Aurora B kinase in Hodgkin lymphoma: immunohistochemical pattern of expression in neoplastic Hodgkin and Reed-Sternberg cells.

Authors: M Ioannou; E Kouvaras; E Stathakis; M Samara; G K Koukoulis
Journal: J Mol Histol Date: 2013-12-24 Impact factor: 2.611

8. Mutations in a gene encoding a midbody protein in binucleated Reed-Sternberg cells of Hodgkin lymphoma.

Authors: Maxwell M Krem; Stephen J Salipante; Marshall S Horwitz
Journal: Cell Cycle Date: 2010-03-02 Impact factor: 4.534

9. Spontaneous and radiation-induced chromosomal instability and persistence of chromosome aberrations after radiotherapy in lymphocytes from prostate cancer patients.

Authors: Andrea Hille; Hana Hofman-Hüther; Elna Kühnle; Barbara Wilken; Margret Rave-Fränk; Heinz Schmidberger; Patricia Virsik
Journal: Radiat Environ Biophys Date: 2009-09-18 Impact factor: 1.925

10. Mitotic errors, aneuploidy and micronuclei in Hodgkin lymphoma pathogenesis.

Authors: Maxwell M Krem; Marshall S Horwitz
Journal: Commun Integr Biol Date: 2013-05-13