Literature DB >> 3955529

Cytogenetic findings in nodular paragranuloma (Hodgkin's disease with lymphocytic predominance; nodular) and in progressively transformed germinal centers.

M L Hansmann, E Gödde-Salz, P K Hui, H K Müller-Hermelink, K Lennert.   

Abstract

Cytogenetic studies were performed in a case of progressively transformed germinal centers (PTGC), and in a case of nodular paragranuloma (NP; Hodgkin's disease with lymphocytic predominance, nodular type). No cytogenetic abnormalities were detected in PTGC. Chromosomal aberrations (hyperdiploidy, 6q-, +21, and several unidentified markers) were found in NP. The results support the proposal that PTGC are reactive in nature and NP is a neoplasm. Chromosomal analysis could provide practical diagnostic aids in the differential diagnosis of PTGC and NP.

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Year:  1986        PMID： 3955529     DOI： 10.1016/0165-4608(86)90212-8

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  7 in total

1.  Chromosome abnormalities in peripheral blood lymphocytes from untreated Hodgkin's patients. A possible evidence for chromosome instability.

Authors:  L Barrios; M R Caballín; R Mirò; C Fuster; G Berrozpe; A Subías; X Batlle; J Egozcue
Journal:  Hum Genet       Date:  1988-04       Impact factor: 4.132

2.  Molecular cytogenetic analyses of immunoglobulin loci in nodular lymphocyte predominant Hodgkin's lymphoma reveal a recurrent IGH-BCL6 juxtaposition.

Authors:  Christoph Renné; José Ignacio Martín-Subero; Martin-Leo Hansmann; Reiner Siebert
Journal:  J Mol Diagn       Date:  2005-08       Impact factor: 5.568

3.  A high number of IgG4-positive plasma cells rules out nodular lymphocyte predominant Hodgkin lymphoma.

Authors:  Kati Kiil; Julia Bein; Bianca Schuhmacher; Lorenz Thurner; Markus Schneider; Martin-Leo Hansmann; Sylvia Hartmann
Journal:  Virchows Arch       Date:  2018-09-26       Impact factor: 4.064

Review 4.  [Nodular lymphocyte-predominant Hodgkin's lymphoma and differential diagnoses].

Authors:  S Hartmann; S Cogliatti; M-L Hansmann
Journal:  Pathologe       Date:  2013-05       Impact factor: 1.011

5.  Detection of numerical karyotype changes in the giant cells of Hodgkin's lymphomas by a combination of FISH and immunohistochemistry applied to paraffin sections.

Authors:  M Nolte; M Werner; R von Wasielewski; G Nietgen; L Wilkens; A Georgii
Journal:  Histochem Cell Biol       Date:  1996-05       Impact factor: 4.304

6.  Hodgkin's disease, lymphocyte predominance type, nodular--further evidence for a B cell derivation. L & H variants of Reed-Sternberg cells express L26, a pan B cell marker.

Authors:  G S Pinkus; J W Said
Journal:  Am J Pathol       Date:  1988-11       Impact factor: 4.307

7.  Nodular Lymphocyte-Predominant Hodgkin Lymphoma in Progressive Transformation of Germinal Centers.

Authors:  C Eric Bailey; Francesca Jung; Benjamin Addicks; Olukemi A Esan; Brian Kellermeyer
Journal:  Case Rep Otolaryngol       Date:  2017-11-14
  7 in total

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