Literature DB >> 1959924

Chromosomal instability in breast cancer patients.

L Barrios1, M R Caballín, R Miró, C Fuster, F Guedea, A Subias, J Egozcue.   

Abstract

We have carried out cytogenetic studies, using the G-banding technique, in peripheral blood lymphocytes of 10 patients affected by breast carcinoma. The frequency of aberrant metaphases (7.36%) is significantly different from that of our laboratory controls (3.76% of aberrant metaphases) but not from that detected in patients suffering from bladder cancer (10.64%) and Hodgkin's disease (11.03%), two conditions that have previously been described as chromosomally unstable. Our results suggest that breast carcinoma patients show a degree of chromosomal instability that could be related to a predisposition to neoplastic disease.

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Year:  1991        PMID： 1959924     DOI： 10.1007/bf00204926

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  17 in total

1.  Chromosome abnormalities in peripheral blood lymphocytes from untreated Hodgkin's patients. A possible evidence for chromosome instability.

Authors:  L Barrios; M R Caballín; R Mirò; C Fuster; G Berrozpe; A Subías; X Batlle; J Egozcue
Journal:  Hum Genet       Date:  1988-04       Impact factor: 4.132

2.  Two identical active X chromosomes in human mammary carcinoma cells.

Authors:  N Wang; E Cedrone; G R Skuse; R Insel; J Dry
Journal:  Cancer Genet Cytogenet       Date:  1990-06

3.  Chromosome instability in bladder carcinoma patients.

Authors:  L Barrios; R Miró; M R Caballín; C Fuster; F Guedea; A Subias; J Egozcue
Journal:  Cancer Genet Cytogenet       Date:  1990-10-01

Review 4.  Genetic instability in the human population: a working hypothesis.

Authors:  T C Hsu
Journal:  Hereditas       Date:  1983       Impact factor: 3.271

5.  Chromosome fragility in patients with sporadic unilateral retinoblastoma.

Authors:  M de Nuñez; V B Penchaszadeh; E Pimentel
Journal:  Cancer Genet Cytogenet       Date:  1984-02

6.  Double minute chromosomes in the leukocytes of a young girl with breast carcinoma.

Authors:  R Madhavi; M Guntur; R Ghosh; P K Ghosh
Journal:  Cancer Genet Cytogenet       Date:  1990-02

7.  Specific chromosome anomalies and predisposition to human breast, renal cell, and colorectal carcinoma.

Authors:  S Pathak; A Goodacre
Journal:  Cancer Genet Cytogenet       Date:  1986-01-01

8.  Chromosomal aberrations and cancer risk.

Authors:  I Nordenson; L Beckman; S Lidén; N Stjernberg
Journal:  Hum Hered       Date:  1984       Impact factor: 0.444

9.  Chromosome damage and sister chromatid exchanges in lymphocyte cultures from patients with two primary cancers.

Authors:  T Brown; A A Dawson; I A McDonald; I Bullock; J L Watt
Journal:  Cancer Genet Cytogenet       Date:  1985-05

10.  Preferential involvement of 11q23-24 and 11p15 in breast cancer.

Authors:  A Ferti-Passantonopoulou; A D Panani; S Raptis
Journal:  Cancer Genet Cytogenet       Date:  1991-02
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  9 in total

1.  Cytogenetic studies on a patient with prepubertal breast cancer: a case report.

Authors:  B R Balsara; T Varughese; A V Bhat; R S Rao; A N Bhisey
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

2.  Chromosomal instability in the lymphocytes of breast cancer patients.

Authors:  Kaur Harsimran; Monga Gaganpreet Kaur; Setia Nitika; Sudan Meena; Uppal M S; Batra A P S; Sambyal Vasudha
Journal:  Indian J Hum Genet       Date:  2009-01

3.  Fluorescence in-situ hybridization technique as a diagnostic and prognostic tool in oral squamous cell carcinoma.

Authors:  Pm Sunil; Cr Ramachandran; S Gokul; N Jaisanghar
Journal:  J Oral Maxillofac Pathol       Date:  2013-01

4.  Chromosomal aberrations in lymphocytes of healthy subjects and risk of cancer.

Authors:  Pavel Rossner; Paolo Boffetta; Marcello Ceppi; Stefano Bonassi; Zdenek Smerhovsky; Karel Landa; Dagmar Juzova; Radim J Srám
Journal:  Environ Health Perspect       Date:  2005-05       Impact factor: 9.031

5.  Why it is crucial to analyze non clonal chromosome aberrations or NCCAs?

Authors:  Henry H Q Heng; Sarah M Regan; Guo Liu; Christine J Ye
Journal:  Mol Cytogenet       Date:  2016-02-13       Impact factor: 2.009

6.  Spontaneous and radiation-induced chromosomal instability and persistence of chromosome aberrations after radiotherapy in lymphocytes from prostate cancer patients.

Authors:  Andrea Hille; Hana Hofman-Hüther; Elna Kühnle; Barbara Wilken; Margret Rave-Fränk; Heinz Schmidberger; Patricia Virsik
Journal:  Radiat Environ Biophys       Date:  2009-09-18       Impact factor: 1.925

7.  Cytogenetic studies in lymphocytes of patients with rectal cancer.

Authors:  E Gebhart; R Romahn; A Schneider; M Hoffmann; D Rau; H Tittelbach
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

8.  Follow-Up Genotoxic Study: Chromosome Damage Two and Six Years after Exposure to the Prestige Oil Spill.

Authors:  Kristin Hildur; Cristina Templado; Jan-Paul Zock; Jesús Giraldo; Francisco Pozo-Rodríguez; Alexandra Frances; Gemma Monyarch; Gema Rodríguez-Trigo; Emma Rodriguez-Rodriguez; Ana Souto; Federico P Gómez; Josep M Antó; Joan Albert Barberà; Carme Fuster
Journal:  PLoS One       Date:  2015-07-29       Impact factor: 3.240

Review 9.  Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems.

Authors:  Christine J Ye; Sarah Regan; Guo Liu; Sarah Alemara; Henry H Heng
Journal:  Mol Cytogenet       Date:  2018-05-10       Impact factor: 2.009
  9 in total

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