Literature DB >> 33577602

Development of a time-resolved mirrorless scintillation detector.

Wonjoong Cheon1,2, Hyunuk Jung1,3, Moonhee Lee1, Jinhyeop Lee1, Sung Jin Kim4, Sungkoo Cho4, Youngyih Han1,5.   

Abstract

PURPOSE: We developed a compact and lightweight time-resolved mirrorless scintillation detector (TRMLSD) employing image processing techniques and a convolutional neural network (CNN) for high-resolution two-dimensional (2D) dosimetry.
METHODS: The TRMLSD comprises a camera and an inorganic scintillator plate without a mirror. The camera was installed at a certain angle from the horizontal plane to collect scintillation from the scintillator plate. The geometric distortion due to the absence of a mirror and camera lens was corrected using a projective transform. Variations in brightness due to the distance between the image sensor and each point on the scintillator plate and the inhomogeneity of the material constituting the scintillator were corrected using a 20.0 × 20.0 cm2 radiation field. Hot pixels were removed using a frame-based noise-reduction technique. Finally, a CNN-based 2D dose distribution deconvolution model was applied to compensate for the dose error in the penumbra region and a lack of backscatter. The linearity, reproducibility, dose rate dependency, and dose profile were tested for a 6 MV X-ray beam to verify dosimeter characteristics. Gamma analysis was performed for two simple and 10 clinical intensity-modulated radiation therapy (IMRT) plans.
RESULTS: The dose linearity with brightness ranging from 0.0 cGy to 200.0 cGy was 0.9998 (R-squared value), and the root-mean-square error value was 1.010. For five consecutive measurements, the reproducibility was within 3% error, and the dose rate dependency was within 1%. The depth dose distribution and lateral dose profile coincided with the ionization chamber data with a 1% mean error. In 2D dosimetry for IMRT plans, the mean gamma passing rates with a 3%/3 mm gamma criterion for the two simple and ten clinical IMRT plans were 96.77% and 95.75%, respectively.
CONCLUSION: The verified accuracy and time-resolved characteristics of the dosimeter may be useful for the quality assurance of machines and patient-specific quality assurance for clinical step-and-shoot IMRT plans.

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Mesh:

Year:  2021        PMID: 33577602      PMCID: PMC7880495          DOI: 10.1371/journal.pone.0246742

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  26 in total

1.  A multiple acquisition sequence for IMRT verification with a 2D ion chamber array.

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Journal:  Med Dosim       Date:  2006       Impact factor: 1.482

2.  The DOSIMAP, a high spatial resolution tissue equivalent 2D dosimeter for LINAC QA and IMRT verification.

Authors:  V Collomb-Patton; P Boher; T Leroux; J M Fontbonne; A Vela; A Batalla
Journal:  Med Phys       Date:  2009-02       Impact factor: 4.071

3.  GafChromic EBT film dosimetry with flatbed CCD scanner: a novel background correction method and full dose uncertainty analysis.

Authors:  Sigrun Saur; Jomar Frengen
Journal:  Med Phys       Date:  2008-07       Impact factor: 4.071

4.  Accurate dosimetry with GafChromic EBT film of a 6 MV photon beam in water: what level is achievable?

Authors:  L J van Battum; D Hoffmans; H Piersma; S Heukelom
Journal:  Med Phys       Date:  2008-02       Impact factor: 4.071

5.  Fast 2D phantom dosimetry for scanning proton beams.

Authors:  S N Boon; P van Luijk; J M Schippers; H Meertens; J M Denis; S Vynckier; J Medin; E Grusell
Journal:  Med Phys       Date:  1998-04       Impact factor: 4.071

6.  Characterization of a GEM-based scintillation detector with He-CF4 gas mixture in clinical proton beams.

Authors:  D Nichiporov; L Coutinho; A V Klyachko
Journal:  Phys Med Biol       Date:  2016-03-18       Impact factor: 3.609

Review 7.  AAPM code of practice for radiotherapy accelerators: report of AAPM Radiation Therapy Task Group No. 45.

Authors:  R Nath; P J Biggs; F J Bova; C C Ling; J A Purdy; J van de Geijn; M S Weinhous
Journal:  Med Phys       Date:  1994-07       Impact factor: 4.071

8.  Comparison of Gafchromic EBT2 and EBT3 films for clinical photon and proton beams.

Authors:  S Reinhardt; M Hillbrand; J J Wilkens; W Assmann
Journal:  Med Phys       Date:  2012-08       Impact factor: 4.071

9.  A spectroscopic study of the chromatic properties of GafChromicEBT3 films.

Authors:  M Callens; W Crijns; V Simons; I De Wolf; T Depuydt; F Maes; K Haustermans; J D'hooge; E D'Agostino; M Wevers; H Pfeiffer; K Van Den Abeele
Journal:  Med Phys       Date:  2016-03       Impact factor: 4.071

10.  Dosimetric study of 2D ion chamber array matrix for the modern radiotherapy treatment verification.

Authors:  Sathiyan Saminathan; Ravikumar Manickam; Varatharaj Chandraraj; Sanjay S Supe
Journal:  J Appl Clin Med Phys       Date:  2010-04-19       Impact factor: 2.102

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