Literature DB >> 33516228

Clinical analysis of pain after transvaginal mesh surgery in patients with pelvic organ prolapse.

Chang Shi1, Ying Zhao1, Qing Hu1, Runqi Gong1, Yitong Yin1, Zhijun Xia2.   

Abstract

BACKGROUND: The purpose of this study was to investigate the relevant factors of pain after transvaginal mesh (TVM) surgery for the treatment of pelvic organ prolapse and to analyse the management and relief of the pain.
METHODS: A multicentre retrospective study of a clinical database of patients who underwent TVM surgery was conducted, and pain related aspects were analysed.
RESULTS: A total of 1855 patients were included in the study. We divided the patients into two groups: pain-free (1805 patients) and pain (50 patients) group. The incidence of pain after TVM surgery was 2.70%, with a median occurrence time of 7.5 months. Pain mainly involved the vagina, perineum, buttocks, groin, inner thighs, and lower abdomen. Excessive intraoperative blood loss (OR = 1.284, 95% CI 0.868-2.401) and postoperative anatomic failure (OR = 1.577, 95% CI 0.952-3.104) were analysed as risk factors with statistical significance. Mesh exposure rate in the pain group was 38%, showing a significant difference between the groups (P < 0.01). Forty patients underwent non-surgical treatment, with a relief rate of 40.0%, 33 patients received surgical treatment, 15 underwent partial mesh removal, and 18 underwent complete mesh removal, with a relief rate of 84.8%. The total relief rate was 88% within all 50 patients suffering from pain.
CONCLUSIONS: Excessive intraoperative bleeding and unsatisfactory postoperative anatomic outcomes can increase the risk of postoperative pain; mesh exposure is also associated with the pain. Most patients can get pain relief with proper management, more than half of whom may need mesh removal with differing approach.

Entities:  

Keywords:  Mesh complications; Pelvic organ prolapse; Postoperative pain; Transvaginal mesh surgery

Mesh:

Year:  2021        PMID: 33516228      PMCID: PMC7847570          DOI: 10.1186/s12905-021-01192-w

Source DB:  PubMed          Journal:  BMC Womens Health        ISSN: 1472-6874            Impact factor:   2.809


  34 in total

1.  Factors associated with exposure of transvaginally placed polypropylene mesh for pelvic organ prolapse.

Authors:  Karen P Gold; Renee M Ward; Carl W Zimmerman; Daniel H Biller; Shawn McGuinn; James C Slaughter; Roger R Dmochowski
Journal:  Int Urogynecol J       Date:  2012-03-24       Impact factor: 2.894

Review 2.  An International Urogynecological Association (IUGA) / International Continence Society (ICS) Joint Report on the Terminology for Female Pelvic Organ Prolapse (POP).

Authors:  Bernard T Haylen; Christopher F Maher; Matthew D Barber; Sérgio Camargo; Vani Dandolu; Alex Digesu; Howard B Goldman; Martin Huser; Alfredo L Milani; Paul A Moran; Gabriel N Schaer; Mariëlla I J Withagen
Journal:  Neurourol Urodyn       Date:  2016-01-07       Impact factor: 2.696

3.  Vaginal mesh contraction: definition, clinical presentation, and management.

Authors:  Benjamin Feiner; Christopher Maher
Journal:  Obstet Gynecol       Date:  2010-02       Impact factor: 7.661

4.  Purely transvaginal/perineal management of complications from commercial prolapse kits using a new prostheses/grafts complication classification system.

Authors:  Farzeen Firoozi; Michael S Ingber; Courtenay K Moore; Sandip P Vasavada; Raymond R Rackley; Howard B Goldman
Journal:  J Urol       Date:  2012-03-15       Impact factor: 7.450

5.  Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT).

Authors:  Cathryn Ma Glazener; Suzanne Breeman; Andrew Elders; Christine Hemming; Kevin G Cooper; Robert M Freeman; Anthony Rb Smith; Fiona Reid; Suzanne Hagen; Isobel Montgomery; Mary Kilonzo; Dwayne Boyers; Alison McDonald; Gladys McPherson; Graeme MacLennan; John Norrie
Journal:  Lancet       Date:  2016-12-21       Impact factor: 79.321

6.  Incidence and Risk Factors for Pelvic Pain After Mesh Implant Surgery for the Treatment of Pelvic Floor Disorders.

Authors:  Elizabeth J Geller; Emma Babb; Andrea G Nackley; Denniz Zolnoun
Journal:  J Minim Invasive Gynecol       Date:  2016-10-20       Impact factor: 4.137

Review 7.  Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse.

Authors:  Christopher Maher; Benjamin Feiner; Kaven Baessler; Corina Christmann-Schmid; Nir Haya; Jane Marjoribanks
Journal:  Cochrane Database Syst Rev       Date:  2016-02-09

8.  Beyond the complications: medium-term anatomical, sexual and functional outcomes following removal of trocar-guided transvaginal mesh. A retrospective cohort study.

Authors:  Stephen T Jeffery; Andri Nieuwoudt
Journal:  Int Urogynecol J       Date:  2012-04-20       Impact factor: 2.894

9.  Progression and remission of pelvic organ prolapse: a longitudinal study of menopausal women.

Authors:  Victoria L Handa; Elizabeth Garrett; Susan Hendrix; Ellen Gold; John Robbins
Journal:  Am J Obstet Gynecol       Date:  2004-01       Impact factor: 8.661

Review 10.  The role of pelvic floor physical therapy in the treatment of pelvic and genital pain-related sexual dysfunction (CME).

Authors:  Talli Y Rosenbaum; Annette Owens
Journal:  J Sex Med       Date:  2008-03       Impact factor: 3.802

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  2 in total

Review 1.  Host-biomaterial interactions in mesh complications after pelvic floor reconstructive surgery.

Authors:  Roxanna E Abhari; Matthew L Izett-Kay; Hayley L Morris; Rufus Cartwright; Sarah J B Snelling
Journal:  Nat Rev Urol       Date:  2021-09-20       Impact factor: 14.432

2.  Tannic acid-loaded hydrogel coating endues polypropylene mesh with hemostatic and anti-inflammatory capacity for facilitating pelvic floor repair.

Authors:  Chenghao Wu; Zixuan Zhou; Xi You; Yi Guo; Ping Chen; Huaifang Li; Xiaowen Tong
Journal:  Regen Biomater       Date:  2022-09-26
  2 in total

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