Literature DB >> 3332755

The impact of genetic engineering on the commercial production of antibiotics by Streptomyces and related bacteria.

C R Hutchinson1.   

Abstract

Developments in Streptomyces genetics that have laid a foundation for this field over the past ten years are reviewed and discussed to suggest how this knowledge might useful for improving the commercial production of antibiotics. This brief analysis predicts a bright future for the application of Streptomyces genetics in antibiotic production.

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Year:  1987        PMID： 3332755     DOI： 10.1007/bf02798365

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN： 0273-2289            Impact factor:   2.926


  116 in total

1.  Phage-mediated cloning of bldA, a region involved in Streptomyces coelicolor morphological development, and its analysis by genetic complementation.

Authors:  J M Piret; K F Chater
Journal:  J Bacteriol       Date:  1985-09       Impact factor: 3.490

2.  Transductional analysis of chloramphenicol biosynthesis genes in Streptomyces venezuelae.

Authors:  S Vats; C Stuttard; L C Vining
Journal:  J Bacteriol       Date:  1987-08       Impact factor: 3.490

3.  Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids.

Authors:  C J Thompson; G S Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

Review 4.  Control of antibiotic biosynthesis.

Authors:  J F Martin; A L Demain
Journal:  Microbiol Rev       Date:  1980-06

5.  Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis.

Authors:  S M Samson; J L Chapman; R Belagaje; S W Queener; T D Ingolia
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

6.  Giant linear plasmids in Streptomyces which code for antibiotic biosynthesis genes.

Authors:  H Kinashi; M Shimaji; A Sakai
Journal:  Nature       Date:  1987 Jul 30-Aug 5       Impact factor: 49.962

7.  Cloning and heterologous expression of a gene cluster for the biosynthesis of tetracenomycin C, the anthracycline antitumor antibiotic of Streptomyces glaucescens.

Authors:  H Motamedi; C R Hutchinson
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

8.  Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremonium.

Authors:  S M Samson; R Belagaje; D T Blankenship; J L Chapman; D Perry; P L Skatrud; R M VanFrank; E P Abraham; J E Baldwin; S W Queener
Journal:  Nature       Date:  1985 Nov 14-20       Impact factor: 49.962

9.  pIJ101, a multi-copy broad host-range Streptomyces plasmid: functional analysis and development of DNA cloning vectors.

Authors:  T Kieser; D A Hopwood; H M Wright; C J Thompson
Journal:  Mol Gen Genet       Date:  1982

10.  Efficient plasmid transformation of Streptomyces ambofaciens and Streptomyces fradiae protoplasts.

Authors:  P Matsushima; R H Baltz
Journal:  J Bacteriol       Date:  1985-07       Impact factor: 3.490
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  8 in total

Review 1.  Compilation and analysis of DNA sequences associated with apparent streptomycete promoters.

Authors:  W R Strohl
Journal:  Nucleic Acids Res       Date:  1992-03-11       Impact factor: 16.971

2.  A macrolide 3-O-acyltransferase gene from the midecamycin-producing species Streptomyces mycarofaciens.

Authors:  O Hara; C R Hutchinson
Journal:  J Bacteriol       Date:  1992-08       Impact factor: 3.490

3.  Disruption of a rhodaneselike gene results in cysteine auxotrophy in Saccharopolyspora erythraea.

Authors:  S Donadio; A Shafiee; C R Hutchinson
Journal:  J Bacteriol       Date:  1990-01       Impact factor: 3.490

4.  Multigene families for anthracycline antibiotic production in Streptomyces peucetius.

Authors:  K J Stutzman-Engwall; C R Hutchinson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

Review 5.  Cellular and metabolic engineering. An overview.

Authors:  D C Cameron; I T Tong
Journal:  Appl Biochem Biotechnol       Date:  1993 Jan-Feb       Impact factor: 2.926

6.  Cloning and expression of daunorubicin biosynthesis genes from Streptomyces peucetius and S. peucetius subsp. caesius.

Authors:  S L Otten; K J Stutzman-Engwall; C R Hutchinson
Journal:  J Bacteriol       Date:  1990-06       Impact factor: 3.490

7.  Expression of doxorubicin-daunorubicin resistance genes in different anthracycline-producing mutants of Streptomyces peucetius.

Authors:  A L Colombo; M M Solinas; G Perini; G Biamonti; G Zanella; M Caruso; F Torti; S Filippini; A Inventi-Solari; L Garofano
Journal:  J Bacteriol       Date:  1992-03       Impact factor: 3.490

8.  Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus).

Authors:  J Vara; M Lewandowska-Skarbek; Y G Wang; S Donadio; C R Hutchinson
Journal:  J Bacteriol       Date:  1989-11       Impact factor: 3.490
  8 in total

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