Ricardo Landini Lutaif Dolci1,2,3, Lígia Tédde de Moraes4, Ana Carolina Mayor de Carvalho4, Jeniffer Cristina Kozechen Rickli4, Jamile Lopes de Souza4, Williams Escalante Encinas5, José Viana Lima Junior6,7, Nilza Maria Scalissi6,7, Américo Rubens Leite Dos Santos6,5,8, Paulo Roberto Lazarini4,6,8. 1. Otolaryngology Departament, Santa Casa de Misericórdia of São Paulo, R. Dr. Cesário Mota Jr, 112-Pavilhão Conde de Lara, 4º andar, São Paulo, SP, Brazil. landini37@hotmail.com. 2. Medical Sciences College at Santa Casa de SP, São Paulo, Brasil. landini37@hotmail.com. 3. Skull Base Surgery Nucleus at Santa Casa of São Paulo, São Paulo, SP, Brazil. landini37@hotmail.com. 4. Otolaryngology Departament, Santa Casa de Misericórdia of São Paulo, R. Dr. Cesário Mota Jr, 112-Pavilhão Conde de Lara, 4º andar, São Paulo, SP, Brazil. 5. Neurosurgery Discipline, Surgery Departament, Santa Casa de Misericórdia of São Paulo, São Paulo, SP, Brazil. 6. Medical Sciences College at Santa Casa de SP, São Paulo, Brasil. 7. Endocrinology and Metabology Discipline, Santa Casa de Misericórdia of São Paulo, São Paulo, SP, Brazil. 8. Skull Base Surgery Nucleus at Santa Casa of São Paulo, São Paulo, SP, Brazil.
Abstract
PURPOSE: This study aimed to evaluate the pre- and post-operative quality-of-life of patients submitted to the resection of pituitary adenoma via endoscopic transsphenoidal. METHODS: This was a prospective study on patients submitted to endoscopic transsphenoidal pituitary surgery with the harvest of a nasoseptal flap who responded to the questionnaires FV-36 and SNOT-22 in the pre-operative and in months 1, 3 and 6 following the surgical procedure. RESULTS: A total of 42 patients submitted to pituitary adenoma resection surgery via endoscopic transsphenoidal with a nasoseptal flap were recruited. In all of the physical and mental domains (SF-36) evaluated, there was an improvement in the long-term evaluation (6 months), compared to the pre-operative, as well as in the site-specific evaluation (SNOT-22). CONCLUSION: The global and site-specific questionnaires in the 6th post-operative month follow-up presented an important improvement in all the physical and mental domains evaluated, as well as in nasal function in the perception of the patients submitted to pituitary adenoma resection via endoscopic transsphenoidal, demonstrating the safety and efficiency of the procedure.
PURPOSE: This study aimed to evaluate the pre- and post-operative quality-of-life of patients submitted to the resection of pituitary adenoma via endoscopic transsphenoidal. METHODS: This was a prospective study on patients submitted to endoscopic transsphenoidal pituitary surgery with the harvest of a nasoseptal flap who responded to the questionnaires FV-36 and SNOT-22 in the pre-operative and in months 1, 3 and 6 following the surgical procedure. RESULTS: A total of 42 patients submitted to pituitary adenoma resection surgery via endoscopic transsphenoidal with a nasoseptal flap were recruited. In all of the physical and mental domains (SF-36) evaluated, there was an improvement in the long-term evaluation (6 months), compared to the pre-operative, as well as in the site-specific evaluation (SNOT-22). CONCLUSION: The global and site-specific questionnaires in the 6th post-operative month follow-up presented an important improvement in all the physical and mental domains evaluated, as well as in nasal function in the perception of the patients submitted to pituitary adenoma resection via endoscopic transsphenoidal, demonstrating the safety and efficiency of the procedure.
Entities:
Keywords:
Hypophyse; Patient health questionnaire; Pituitary adenoma; Quality-of-life; Skull base
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