Literature DB >> 3265103

Non-stationary spatial filtering and accelerated curve fitting for parametric imaging with dynamic PET.

K Herholz1.   

Abstract

A non-stationary spatial low pass filter was developed and implemented in combination with an accelerated non-linear curve fitting routine to create low noise-high contrast images of physiological parameters with dynamic positron emission tomography. The method was applied to 18F-2-fluoro-2-deoxyglucose (FDG) studies, and images of local blood volume, kinetic rate constants, precursor pool volume and glucose metabolism were generated. Noise reduction and contrast preservation was demonstrated in a simulated pie phantom and a study of a patient with a recent brain infarct. Considerably improvement in quantitative accuracy of pixel parameter values was observed in the phantom study in comparison with unprocessed or conventionally smoothed images.

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Year:  1988        PMID: 3265103     DOI: 10.1007/bf00252392

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN: 0340-6997


  28 in total

1.  Additional tables of the probability of runs of correct responses in learning and problem-solving.

Authors:  D A GRANT
Journal:  Psychol Bull       Date:  1947-05       Impact factor: 17.737

2.  Quantification of neuroreceptors in the living human brain. I. Irreversible binding of ligands.

Authors:  D F Wong; A Gjedde; H N Wagner
Journal:  J Cereb Blood Flow Metab       Date:  1986-04       Impact factor: 6.200

3.  A Wiener filter for nuclear medicine images.

Authors:  M A King; P W Doherty; R B Schwinger; B C Penney
Journal:  Med Phys       Date:  1983 Nov-Dec       Impact factor: 4.071

4.  Fast count-dependent digital filtering of nuclear medicine images: concise communication.

Authors:  M A King; P W Doherty; R B Schwinger; D A Jacobs; R E Kidder; T R Miller
Journal:  J Nucl Med       Date:  1983-11       Impact factor: 10.057

5.  Correction for scattered radiation in a ring detector positron camera by integral transformation of the projections.

Authors:  M Bergström; L Eriksson; C Bohm; G Blomqvist; J Litton
Journal:  J Comput Assist Tomogr       Date:  1983-02       Impact factor: 1.826

6.  Determination of object contour from projections for attenuation correction in cranial positron emission tomography.

Authors:  M Bergström; J Litton; L Eriksson; C Bohm; G Blomqvist
Journal:  J Comput Assist Tomogr       Date:  1982-04       Impact factor: 1.826

7.  Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: validation of method.

Authors:  M E Phelps; S C Huang; E J Hoffman; C Selin; L Sokoloff; D E Kuhl
Journal:  Ann Neurol       Date:  1979-11       Impact factor: 10.422

8.  Effect of ischemia on quantification of local cerebral glucose metabolic rate in man.

Authors:  R A Hawkins; M E Phelps; S C Huang; D E Kuhl
Journal:  J Cereb Blood Flow Metab       Date:  1981       Impact factor: 6.200

9.  Comparative regional analysis of 2-fluorodeoxyglucose and methylglucose uptake in brain of four stroke patients. With special reference to the regional estimation of the lumped constant.

Authors:  A Gjedde; K Wienhard; W D Heiss; G Kloster; N H Diemer; K Herholz; G Pawlik
Journal:  J Cereb Blood Flow Metab       Date:  1985-06       Impact factor: 6.200

10.  The influence of tissue heterogeneity on results of fitting nonlinear model equations to regional tracer uptake curves: with an application to compartmental models used in positron emission tomography.

Authors:  K Herholz; C S Patlak
Journal:  J Cereb Blood Flow Metab       Date:  1987-04       Impact factor: 6.200

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  3 in total

1.  A gradient-based method for segmenting FDG-PET images: methodology and validation.

Authors:  Xavier Geets; John A Lee; Anne Bol; Max Lonneux; Vincent Grégoire
Journal:  Eur J Nucl Med Mol Imaging       Date:  2007-03-13       Impact factor: 9.236

2.  FDG transport and phosphorylation in human gliomas measured with dynamic PET.

Authors:  K Herholz; J Rudolf; W D Heiss
Journal:  J Neurooncol       Date:  1992-02       Impact factor: 4.130

3.  Nonlinear spatio-temporal filtering of dynamic PET data using a four-dimensional Gaussian filter and expectation-maximization deconvolution.

Authors:  J M Floberg; J E Holden
Journal:  Phys Med Biol       Date:  2013-02-21       Impact factor: 3.609

  3 in total

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