| Literature DB >> 32573388 |
Alexandre Boutet1, Clement T Chow1, Keshav Narang1, Gavin J B Elias1, Clemens Neudorfer1, Jürgen Germann1, Manish Ranjan1, Aaron Loh1, Alastair J Martin1, Walter Kucharczyk1, Christopher J Steele1, Ileana Hancu1, Ali R Rezai1, Andres M Lozano1.
Abstract
MRI is a valuable clinical and research tool for patients undergoing deep brain stimulation (DBS). However, risks associated with imaging DBS devices have led to stringent regulations, limiting the clinical and research utility of MRI in these patients. The main risks in patients with DBS devices undergoing MRI are heating at the electrode tips, induced currents, implantable pulse generator dysfunction, and mechanical forces. Phantom model studies indicate that electrode tip heating remains the most serious risk for modern DBS devices. The absence of adverse events in patients imaged under DBS vendor guidelines for MRI demonstrates the general safety of MRI for patients with DBS devices. Moreover, recent work indicates that-given adequate safety data-patients may be imaged outside these guidelines. At present, investigators are primarily focused on improving DBS device and MRI safety through the development of tools, including safety simulation models. Existing guidelines provide a standardized framework for performing safe MRI in patients with DBS devices. It also highlights the possibility of expanding MRI as a tool for research and clinical care in these patients going forward. © RSNA, 2020.Entities:
Mesh:
Year: 2020 PMID: 32573388 PMCID: PMC7543718 DOI: 10.1148/radiol.2020192291
Source DB: PubMed Journal: Radiology ISSN: 0033-8419 Impact factor: 11.105