Literature DB >> 32424713

Improved blood culture workflow in the time to detection of microorganisms placing incubators systems outside of microbiology laboratory.

M Angeles Orellana1,2, Fernando Chaves3,4, Rafael Delgado3,4.   

Abstract

PURPOSE: We analyzed the workflow of the blood culture procedure with one blood culture incubator in the microbiology laboratory, in comparison with the workflow with the incubators systems placing outside, and in a microbiology laboratory without 24-h staffing.
METHODS: We assessed the elapsed time (ET) and time-to-result (TTR) in the two laboratory workflows during 1 month period in consecutive years. First period with one BACT/ALERT 3D module located in the microbiology laboratory (ML) (access 8 a.m. to 10 p.m.) and second period with three BACT/ALERT VIRTUO modules (one located in ML and two in the core sample laboratory, access 24 h).
RESULTS: The mean ET with BACT/ALERT 3D was 7.09 ± 6.15 h and 1.32 ± 3.14 h with BACT/ALERT VIRTUO. During the 8:00 a.m. to 10:00 p.m. shift, the average ETs were 3.54 ± 5.06 vs 1.59 ± 1.29 h for the two time periods, respectively. Since the automated loading of bottles on the BACT/ALERT VIRTUO allows processing of blood cultures during the night shift, there was a significant reduction of time during the 10:00 p.m. to 8:00 a.m. shift, where the average ET was 10.52 ± 5.23 vs 1.00 ± 4.40 h, respectively. The percentage of positivity in the first period was 9.03% and 11.18% in the second (p = 0.0003). The average TTR in the first period was 24.78 ± 15.9 h and 16.85 ± 14.13 h in the second (p < 0.0001).
CONCLUSIONS: Easy 24-h access to blood culture incubators resulted in significant improvement in the workflow of blood culture, decreasing ET, and therefore decreasing the time to positivity and the efficiency of recovery.

Keywords:  Blood culture incubator; Bloodstream infections; Elapsed time; Workflow blood culture

Mesh:

Year:  2020        PMID: 32424713      PMCID: PMC7455611          DOI: 10.1007/s42770-020-00298-x

Source DB:  PubMed          Journal:  Braz J Microbiol        ISSN: 1517-8382            Impact factor:   2.476


  12 in total

1.  Delayed insertion of blood culture bottles into automated continuously monitoring blood culture systems increases the time from blood sample collection to the detection of microorganisms in bacteremic patients.

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Journal:  J Infect Chemother       Date:  2009-03-12       Impact factor: 2.211

2.  Reduced length of hospital stay through a point of care placed automated blood culture instrument.

Authors:  M J Bruins; M J Egbers; T M Israel; S H A Diepeveen; M J H M Wolfhagen
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3.  Blood Culture Turnaround Time in U.S. Acute Care Hospitals and Implications for Laboratory Process Optimization.

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Journal:  J Clin Microbiol       Date:  2018-11-27       Impact factor: 5.948

Review 4.  Rapid phenotypic methods to improve the diagnosis of bacterial bloodstream infections: meeting the challenge to reduce the time to result.

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Journal:  Clin Microbiol Infect       Date:  2018-03-29       Impact factor: 8.067

5.  Consequences of Implementing a "Better" Blood Culture System.

Authors:  Sarah E Posillico; Joseph F Golob; Brenda M Zosa; Nitin Sajankila; Laura A Kreiner; Jeffrey A Claridge
Journal:  Surg Infect (Larchmt)       Date:  2018-05-29       Impact factor: 2.150

Review 6.  Diagnosis of bloodstream infections from positive blood cultures and directly from blood samples: recent developments in molecular approaches.

Authors:  N Peker; N Couto; B Sinha; J W Rossen
Journal:  Clin Microbiol Infect       Date:  2018-05-19       Impact factor: 8.067

7.  Implementation of the new VIRTUO blood culture system: evaluation and comparison to the 3D system using simulated blood cultures.

Authors:  Nathalie Miller; Laetitia Brassinne; Daniel Allemeersch
Journal:  Acta Clin Belg       Date:  2017-06-05       Impact factor: 1.264

8.  Epidemiology of sepsis in Germany: results from a national prospective multicenter study.

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Journal:  Intensive Care Med       Date:  2007-02-24       Impact factor: 17.440

9.  Impact of Pre-Analytical Time on the Recovery of Pathogens from Blood Cultures: Results from a Large Retrospective Survey.

Authors:  Claudia Venturelli; Elena Righi; Lucia Borsari; Gabriella Aggazzotti; Stefano Busani; Cristina Mussini; Fabio Rumpianesi; Gian Maria Rossolini; Massimo Girardis
Journal:  PLoS One       Date:  2017-01-03       Impact factor: 3.240

10.  Quality of blood culture testing - a survey in intensive care units and microbiological laboratories across four European countries.

Authors:  Roland P H Schmitz; Peter M Keller; Michael Baier; Stefan Hagel; Mathias W Pletz; Frank M Brunkhorst
Journal:  Crit Care       Date:  2013-10-21       Impact factor: 9.097

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