Literature DB >> 32413009

Validation of an Automated Early Treatment Diabetic Retinopathy Study Low-contrast Letter Acuity Test.

Yi Pang, Lauren Sparschu1, Elyse Nylin1, Jingyun Wang2.   

Abstract

SIGNIFICANCE: Automated low-contrast letter acuity (LCLA) has several advantages: consistent luminance, reduced chance of individuals memorizing test letters, and convenient and accurate visual acuity reporting functions. Although automated LCLA might report slightly worse acuity than Sloan LCLA chart, considering its advantages, it may be a viable alternative to Sloan LCLA chart in clinical practice and research.
PURPOSE: The purpose of this study was to determine the repeatability of an automated LCLA measurement and its agreement with the Sloan LCLA chart test in normal participants and reduced-vision participants.
METHODS: Adult participants (n = 49) were measured with both automated Early Treatment Diabetic Retinopathy Study and Sloan LCLA tests, including normal and reduced-vision groups. Low-contrast letter acuity at two contrast levels (2.5 and 10%) was measured at 3 m in a random sequence with both LCLA tests. To test repeatability, participants were retested 1 week later. Repeatability of the two tests between two visits and agreement between automated and Sloan LCLA tests were evaluated using 95% limits of agreement.
RESULTS: In terms of the 95% limits of agreement, the repeatability of both tests was as follows: automated LCLA at 2.5%, ±0.26; automated LCLA at 10%, ±0.22; Sloan LCLA at 2.5%, ±0.23, and Sloan LCLA at 10%, ±0.16. The agreement of the two tests was as follows: ±0.19 at 2.5% and ±0.24 at 10%. The automated LCLA at 2.5 and 10% levels was generally reported one-half to one logMAR line lower than Sloan LCLA (mean differences, -0.04 at 2.5% and -0.13 at 10%; paired t test, P < .05).
CONCLUSIONS: The automated LCLA test shows fairly good test-retest repeatability at both 2.5 and 10% contrast levels. The agreement between the automated and the Sloan low-contrast letter acuity tests was comparable with test-retest agreement. Although the automated LCLA test reports slightly worse acuity than the Sloan LCLA test, it could be an appropriate alternative to the Sloan LCLA test.

Entities:  

Mesh:

Year:  2020        PMID: 32413009      PMCID: PMC7370921          DOI: 10.1097/OPX.0000000000001506

Source DB:  PubMed          Journal:  Optom Vis Sci        ISSN: 1040-5488            Impact factor:   2.106


  17 in total

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Authors:  Bradley E Dougherty; Roanne E Flom; Mark A Bullimore
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2.  Visual acuity versus letter contrast sensitivity in early cataract.

Authors:  D B Elliott; P Situ
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3.  Validation of an iPad test of letter contrast sensitivity.

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4.  One eye or two: a comparison of binocular and monocular low-contrast acuity testing in multiple sclerosis.

Authors:  Stacy L Pineles; Eileen E Birch; Lauren S Talman; David J Sackel; Elliot M Frohman; Peter A Calabresi; Steven L Galetta; Maureen G Maguire; Laura J Balcer
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5.  New low-contrast vision charts: reliability and test characteristics in patients with multiple sclerosis.

Authors:  L J Balcer; M L Baier; V S Pelak; R J Fox; S Shuwairi; S L Galetta; G R Cutter; M G Maguire
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6.  Statistical methods for assessing agreement between two methods of clinical measurement.

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7.  The National Eye Institute Visual Function Questionnaire: experience of the ONTT. Optic Neuritis Treatment Trial.

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9.  Letter contrast sensitivity changes in early diabetic retinopathy.

Authors:  Efty P Stavrou; Joanne M Wood
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Review 10.  Validity of low-contrast letter acuity as a visual performance outcome measure for multiple sclerosis.

Authors:  Laura J Balcer; Jenelle Raynowska; Rachel Nolan; Steven L Galetta; Raju Kapoor; Ralph Benedict; Glenn Phillips; Nicholas LaRocca; Lynn Hudson; Richard Rudick
Journal:  Mult Scler       Date:  2017-02-16       Impact factor: 6.312

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  3 in total

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