Literature DB >> 32406018

Cervical cancer and potential pharmacological treatment with snake venoms.

Alejandro Montoya-Gómez1, Leonel Montealegre-Sánchez2, Herney Andrés García-Perdomo3, Eliécer Jiménez-Charris4.   

Abstract

Cervical cancer is the fourth most common cancer worldwide in women. Apoptosis reactivation has become the main strategy for decreasing cancer proliferation. There is a need to extend the search for new drugs to implement more effective and less toxic strategies for cervical cancer treatment. Research has been carried out to find new drugs that have minimal side effects and that focus on the tumor microenvironment, particularly in the induction of cellular apoptosis and cell migration and the inhibition of angiogenesis. Potent toxins from snake venoms have shown potential as sources for the synthesis of new drugs with such characteristics. The present work aimed to describe cervical cancer characteristics, associated risk factors, current treatments and to highlight the effects of toxins isolated from the venom of snakes of the Viperidae family on cervical cancer cell lines.

Entities:  

Keywords:  Anticancer agent; Apoptosis; Cytotoxicity; Toxins; Translational medicine; Tumor cell lines

Mesh:

Substances:

Year:  2020        PMID: 32406018     DOI: 10.1007/s11033-020-05503-6

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN: 0301-4851            Impact factor:   2.742


  64 in total

1.  Epidemiology of cervical cancer in Colombia.

Authors:  Nubia Muñoz; Luis Eduardo Bravo
Journal:  Salud Publica Mex       Date:  2014 Sep-Oct

2.  Impact of scaled up human papillomavirus vaccination and cervical screening and the potential for global elimination of cervical cancer in 181 countries, 2020-99: a modelling study.

Authors:  Kate T Simms; Julia Steinberg; Michael Caruana; Megan A Smith; Jie-Bin Lew; Isabelle Soerjomataram; Philip E Castle; Freddie Bray; Karen Canfell
Journal:  Lancet Oncol       Date:  2019-02-19       Impact factor: 41.316

3.  Plerixafor Improves Primary Tumor Response and Reduces Metastases in Cervical Cancer Treated with Radio-Chemotherapy.

Authors:  Naz Chaudary; Melania Pintilie; Salomeh Jelveh; Patricia Lindsay; Richard P Hill; Michael Milosevic
Journal:  Clin Cancer Res       Date:  2016-10-03       Impact factor: 12.531

4.  Image guided brachytherapy in locally advanced cervical cancer: Improved pelvic control and survival in RetroEMBRACE, a multicenter cohort study.

Authors:  Alina Sturdza; Richard Pötter; Lars Ulrik Fokdal; Christine Haie-Meder; Li Tee Tan; Renaud Mazeron; Primoz Petric; Barbara Šegedin; Ina Maria Jurgenliemk-Schulz; Christel Nomden; Charles Gillham; Orla McArdle; Erik Van Limbergen; Hilde Janssen; Peter Hoskin; Gerry Lowe; Ekkasit Tharavichitkul; Elena Villafranca; Umesh Mahantshetty; Petra Georg; Kathrin Kirchheiner; Christian Kirisits; Kari Tanderup; Jacob Christian Lindegaard
Journal:  Radiother Oncol       Date:  2016-04-29       Impact factor: 6.280

Review 5.  Therapeutic potential of snake venom in cancer therapy: current perspectives.

Authors:  Vivek Kumar Vyas; Keyur Brahmbhatt; Hardik Bhatt; Utsav Parmar
Journal:  Asian Pac J Trop Biomed       Date:  2013-02

6.  Projections of global mortality and burden of disease from 2002 to 2030.

Authors:  Colin D Mathers; Dejan Loncar
Journal:  PLoS Med       Date:  2006-11       Impact factor: 11.069

7.  Editorial: Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

Authors:  Kulmira Nurgali; R Thomas Jagoe; Raquel Abalo
Journal:  Front Pharmacol       Date:  2018-03-22       Impact factor: 5.810

8.  Systematic review and meta-analysis of the prognostic significance of microRNAs in cervical cancer.

Authors:  Zhilan Chen; Yingyan Han; Chengwen Song; Huafang Wei; Ying Chen; Kecheng Huang; Shuang Li; Ding Ma; Shixuan Wang; Jing Wang; Qiping Lu
Journal:  Oncotarget       Date:  2017-12-16

9.  Cancer incidence estimates and mortality for the top five cancer in Colombia, 2007-2011.

Authors:  Constanza Pardo; Ricardo Cendales
Journal:  Colomb Med (Cali)       Date:  2018-03-30

10.  Natural Occurrence of Beauvericin and Enniatins in Corn- and Wheat-Based Samples Harvested in 2017 Collected from Shandong Province, China.

Authors:  Xiaomin Han; Wenjing Xu; Jing Zhang; Jin Xu; Fengqin Li
Journal:  Toxins (Basel)       Date:  2018-12-27       Impact factor: 4.546

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  1 in total

1.  Pllans-II Induces Cell Death in Cervical Cancer Squamous Epithelial Cells via Unfolded Protein Accumulation and Endoplasmic Reticulum Stress.

Authors:  Alejandro Montoya-Gómez; Nelson Rivera Franco; Leonel Ives Montealegre-Sanchez; Luis Manuel Solano-Redondo; Andrés Castillo; Mildrey Mosquera-Escudero; Eliécer Jiménez-Charris
Journal:  Molecules       Date:  2022-10-01       Impact factor: 4.927

  1 in total

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