Literature DB >> 23593597

Therapeutic potential of snake venom in cancer therapy: current perspectives.

Vivek Kumar Vyas1, Keyur Brahmbhatt, Hardik Bhatt, Utsav Parmar.   

Abstract

Many active secretions produced by animals have been employed in the development of new drugs to treat diseases such as hypertension and cancer. Snake venom toxins contributed significantly to the treatment of many medical conditions. There are many published studies describing and elucidating the anti-cancer potential of snake venom. Cancer therapy is one of the main areas for the use of protein peptides and enzymes originating from animals of different species. Some of these proteins or peptides and enzymes from snake venom when isolated and evaluated may bind specifically to cancer cell membranes, affecting the migration and proliferation of these cells. Some of substances found in the snake venom present a great potential as anti-tumor agent. In this review, we presented the main results of recent years of research involving the active compounds of snake venom that have anticancer activity.

Entities:  

Keywords:  Anticancer agents; Apoptosis inducer; Cytotoxin; Snake venom

Mesh:

Substances:

Year:  2013        PMID: 23593597      PMCID: PMC3627178          DOI: 10.1016/S2221-1691(13)60042-8

Source DB:  PubMed          Journal:  Asian Pac J Trop Biomed        ISSN: 2221-1691


  51 in total

Review 1.  Snake venom components affecting blood coagulation and the vascular system: structural similarities and marked diversity.

Authors:  Yasuo Yamazaki; Takashi Morita
Journal:  Curr Pharm Des       Date:  2007       Impact factor: 3.116

2.  ACTX-8, a cytotoxic L-amino acid oxidase isolated from Agkistrodon acutus snake venom, induces apoptosis in Hela cervical cancer cells.

Authors:  Liang Zhang; Li-Jun Wei
Journal:  Life Sci       Date:  2007-01-12       Impact factor: 5.037

3.  A nesting of vipers: Phylogeny and historical biogeography of the Viperidae (Squamata: Serpentes).

Authors:  Wolfgang Wüster; Lindsay Peppin; Catharine E Pook; Daniel E Walker
Journal:  Mol Phylogenet Evol       Date:  2008-09-03       Impact factor: 4.286

4.  Fatality in a case of envenomation by Crotalus adamanteus initially successfully treated with polyvalent ovine antivenom followed by recurrence of defibrinogenation syndrome.

Authors:  Craig Kitchens; Thomas Eskin
Journal:  J Med Toxicol       Date:  2008-09

5.  Antitumoural effect of an L-amino acid oxidase isolated from Bothrops jararaca snake venom.

Authors:  Mariana M de Vieira Santos; Carolina D Sant'Ana; José R Giglio; Reinaldo J da Silva; Suely V Sampaio; Andreimar M Soares; Denise Fecchio
Journal:  Basic Clin Pharmacol Toxicol       Date:  2008-03-16       Impact factor: 4.080

6.  Snake venomics of the Brazilian pitvipers Bothrops cotiara and Bothrops fonsecai. Identification of taxonomy markers.

Authors:  Alexandre K Tashima; Libia Sanz; Antonio C M Camargo; Solange M T Serrano; Juan J Calvete
Journal:  J Proteomics       Date:  2008-08-07       Impact factor: 4.044

Review 7.  Snake venom phospholipase A2 inhibitors: medicinal chemistry and therapeutic potential.

Authors:  Silvana Marcussi; Carolina D Sant'Ana; Clayton Z Oliveira; Aristides Quintero Rueda; Danilo L Menaldo; Rene O Beleboni; Rodrigo G Stabeli; José R Giglio; Marcos R M Fontes; Andreimar M Soares
Journal:  Curr Top Med Chem       Date:  2007       Impact factor: 3.295

8.  Nucleotidase and DNase activities in Brazilian snake venoms.

Authors:  Paulo Bruno Valadão Sales; Marcelo L Santoro
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2007-08-21       Impact factor: 3.228

9.  Inhibition of Hep2 and HeLa cell proliferation in vitro and EAC tumor growth in vivo by Lapemis curtus (Shaw 1802) venom.

Authors:  R Karthikeyan; S Karthigayan; M Sri Balasubashini; S T Somasundaram; T Balasubramanian
Journal:  Toxicon       Date:  2007-09-02       Impact factor: 3.033

10.  A cytotoxin isolated from Agkistrodon acutus snake venom induces apoptosis via Fas pathway in A549 cells.

Authors:  Liang Zhang; Li Cui
Journal:  Toxicol In Vitro       Date:  2007-04-27       Impact factor: 3.500

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  40 in total

1.  Morulustatin, A Disintegrin that Inhibits ADP-Induced Platelet Aggregation, Isolated from the Mexican Tamaulipan Rock Rattlesnake (Crotalus lepidus morulus).

Authors:  Miguel Borja; Jacob Anthony Galan; Esteban Cantu; Alejandro Zugasti-Cruz; Alexis Rodríguez-Acosta; David Lazcano; Sara Lucena; Montamas Suntravat; Y Elda Eliza Sánchez
Journal:  Rev Cient (Maracaibo)       Date:  2016 Mar-Apr       Impact factor: 0.444

2.  Inhibition of pancreatic tumoral cells by snake venom disintegrins.

Authors:  Sara Lucena; Roberto Castro; Courtney Lundin; Amanda Hofstetter; Amber Alaniz; Montamas Suntravat; Elda Eliza Sánchez
Journal:  Toxicon       Date:  2014-11-20       Impact factor: 3.033

3.  Anti-Cancer Effect of Moroccan Cobra Naja haje Venom and Its Fractions against Hepatocellular Carcinoma in 3D Cell Culture.

Authors:  Ayoub Lafnoune; Su-Yeon Lee; Jin-Yeong Heo; Imane Gourja; Bouchra Darkaoui; Zaineb Abdelkafi-Koubaa; Fatima Chgoury; Khadija Daoudi; Salma Chakir; Rachida Cadi; Khadija Mounaji; Najet Srairi-Abid; Naziha Marrakchi; David Shum; Haeng-Ran Seo; Naoual Oukkache
Journal:  Toxins (Basel)       Date:  2021-06-04       Impact factor: 4.546

Review 4.  Perspectives and controversies regarding the use of natural products for the treatment of lung cancer.

Authors:  Tingting Wen; Lei Song; Shucheng Hua
Journal:  Cancer Med       Date:  2021-03-02       Impact factor: 4.452

Review 5.  Cervical cancer and potential pharmacological treatment with snake venoms.

Authors:  Alejandro Montoya-Gómez; Leonel Montealegre-Sánchez; Herney Andrés García-Perdomo; Eliécer Jiménez-Charris
Journal:  Mol Biol Rep       Date:  2020-05-13       Impact factor: 2.742

6.  Exploring the Potential of Venom from Nasonia vitripennis as Therapeutic Agent with High-Throughput Screening Tools.

Authors:  Ellen L Danneels; Ellen M Formesyn; Dirk C de Graaf
Journal:  Toxins (Basel)       Date:  2015-06-03       Impact factor: 4.546

Review 7.  Antitumoral activity of snake venom proteins: new trends in cancer therapy.

Authors:  Leonardo A Calderon; Juliana C Sobrinho; Kayena D Zaqueo; Andrea A de Moura; Amy N Grabner; Maurício V Mazzi; Silvana Marcussi; Auro Nomizo; Carla F C Fernandes; Juliana P Zuliani; Bruna M A Carvalho; Saulo L da Silva; Rodrigo G Stábeli; Andreimar M Soares
Journal:  Biomed Res Int       Date:  2014-02-13       Impact factor: 3.411

Review 8.  Novel Anticancer and Treatment Sensitizing Compounds against Pancreatic Cancer.

Authors:  Gabrielle Wishart; Priyanka Gupta; Andrew Nisbet; Eirini Velliou; Giuseppe Schettino
Journal:  Cancers (Basel)       Date:  2021-06-11       Impact factor: 6.639

9.  Elapid snake venom analyses show the specificity of the peptide composition at the level of genera Naja and Notechis.

Authors:  Aisha Munawar; Maria Trusch; Dessislava Georgieva; Diana Hildebrand; Marcel Kwiatkowski; Henning Behnken; Sönke Harder; Raghuvir Arni; Patrick Spencer; Hartmut Schlüter; Christian Betzel
Journal:  Toxins (Basel)       Date:  2014-02-28       Impact factor: 4.546

10.  The Metabolomic Profiles of Sera of Mice Infected with Plasmodium berghei and Treated by Effective Fraction of Naja naja oxiana Using 1H Nuclear Magnetic Resonance Spectroscopy.

Authors:  Fateme Hajialiani; Delavar Shahbazzadeh; Fatemeh Maleki; Taher Elmi; Fatemeh Tabatabaie; Zahra Zamani
Journal:  Acta Parasitol       Date:  2021-08-06       Impact factor: 1.440

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