Literature DB >> 3229178

A novel centromeric repetitive DNA from human chromosome 22.

R Metzdorf1, E Göttert, N Blin.   

Abstract

A recombinant DNA clone localized in the centromeric region of chromosome 22 was isolated from a flow-sorted human chromosome 22 DNA library. When the original insert of about 1.9 kb was used to probe Southern blots of EcoRI-digested genomic DNA it revealed at least 40 fragments. A comparable pattern was obtained with each of the three subclones (800, 700, and 380 bp). In situ hybridization showed signals clustered in the region 22cen. DNA sequence analysis using the 380 bp fragment subcloned in pTZ18/19 (p22hom48.4) revealed eight copies of a 48 bp repeat and the size of hybridizing restriction fragments indicated that this tandemly repeated sequence is spread over a region of a few hundred kilobases. Whereas this novel DNA, termed D22Z3, displayed no sequence homology to rodent and monkey genomes cross-homology was discernible for DNA from two great ape species.

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Year:  1988        PMID： 3229178     DOI： 10.1007/bf00327372

Source DB:  PubMed          Journal:  Chromosoma        ISSN： 0009-5915            Impact factor:   4.316


  19 in total

1.  The molecular clock runs more slowly in man than in apes and monkeys.

Authors:  W H Li; M Tanimura
Journal:  Nature       Date:  1987 Mar 5-11       Impact factor: 49.962

2.  Characterization of a human 'midisatellite' sequence.

Authors:  Y Nakamura; C Julier; R Wolff; T Holm; P O'Connell; M Leppert; R White
Journal:  Nucleic Acids Res       Date:  1987-03-25       Impact factor: 16.971

3.  Nucleotide sequence heterogeneity of alpha satellite repetitive DNA: a survey of alphoid sequences from different human chromosomes.

Authors:  J S Waye; H F Willard
Journal:  Nucleic Acids Res       Date:  1987-09-25       Impact factor: 16.971

4.  Organization and evolution of alpha satellite DNA from human chromosome 11.

Authors:  J S Waye; L A Creeper; H F Willard
Journal:  Chromosoma       Date:  1987       Impact factor: 4.316

5.  Hypervariable 'minisatellite' regions in human DNA.

Authors:  A J Jeffreys; V Wilson; S L Thein
Journal:  Nature       Date:  1985 Mar 7-13       Impact factor: 49.962

6.  Isolation of the complementary strands of a human satellite DNA.

Authors:  G Corneo; E Ginelli; E Polli
Journal:  J Mol Biol       Date:  1968-04-14       Impact factor: 5.469

7.  A human glioblastoma line with karyotypic nullisomy 13 containing several chromosome 13-specific sequences.

Authors:  K D Zang; H Fischer; A van der Hout; G Unteregger; W Henn; H Scheffer; C Wollenberg; C H Buys; N Blin
Journal:  Cancer Genet Cytogenet       Date:  1988-07-01

8.  A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia.

Authors:  A de Klein; A G van Kessel; G Grosveld; C R Bartram; A Hagemeijer; D Bootsma; N K Spurr; N Heisterkamp; J Groffen; J R Stephenson
Journal:  Nature       Date:  1982-12-23       Impact factor: 49.962

9.  DNA strand reassociation and polyribonucleotide binding in the African green monkey, Cercopithecus aethiops.

Authors:  J J Maio
Journal:  J Mol Biol       Date:  1971-03-28       Impact factor: 5.469

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  19 in total

1.  The chAB4 and NF1-related long-range multisequence DNA families are contiguous in the centromeric heterochromatin of several human chromosomes.

Authors:  Imre Cserpán; Róbert Katona; Tünde Praznovszky; Edit Novák; Márta Rózsavölgyi; Erika Csonka; Mónika Mórocz; Katalin Fodor; Gyula Hadlaczky
Journal:  Nucleic Acids Res       Date:  2002-07-01       Impact factor: 16.971

2.  Prototypic sequences for human repetitive DNA.

Authors:  J Jurka; J Walichiewicz; A Milosavljevic
Journal:  J Mol Evol       Date:  1992-10       Impact factor: 2.395

3.  Characterisation of a boundary between satellite III and alphoid sequences on human chromosome 10.

Authors:  M S Jackson; S E Mole; B A Ponder
Journal:  Nucleic Acids Res       Date:  1992-09-25       Impact factor: 16.971

4.  Chromosomal origin of small ring marker chromosomes in man: characterization by molecular genetics.

Authors:  D F Callen; H J Eyre; M L Ringenbergs; C J Freemantle; P Woodroffe; E A Haan
Journal:  Am J Hum Genet       Date:  1991-04       Impact factor: 11.025

Review 5.  Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved "chromatin folding code".

Authors:  P Vogt
Journal:  Hum Genet       Date:  1990-03       Impact factor: 4.132

6.  Isolation of anonymous DNA markers for human chromosome 22q11 from a flow-sorted library, and mapping using hybrids from patients with DiGeorge syndrome.

Authors:  A M Sharkey; L McLaren; M Carroll; J Fantes; D Green; D Wilson; P J Scambler; H J Evans
Journal:  Hum Genet       Date:  1992-04       Impact factor: 4.132

7.  Distribution and linkage of repetitive clusters from the heterochromatic region of human chromosome 22.

Authors:  R Müllenbach; C Pusch; K Holzmann; R Suijkerbuijk; N Blin
Journal:  Chromosome Res       Date:  1996-06       Impact factor: 5.239

8.  Expressed sequences within pericentromeric heterochromatin of human chromosome 22.

Authors:  N Blin; M Scholz; B Wissinger; R Müllenbach; C Pusch
Journal:  Mamm Genome       Date:  1997       Impact factor: 2.957

9.  Cytogenetic and in situ DNA-hybridization studies in intracranial tumors of a patient with central neurofibromatosis.

Authors:  B Wullich; M Kiechle-Schwarz; L Mayfrank; W Schempp
Journal:  Hum Genet       Date:  1989-04       Impact factor: 4.132

10.  Regional localization and molecular characterization of a DNA sequence on the long arm of chromosome 22.

Authors:  E Göttert; R Metzdorf; U Färber; N Blin
Journal:  Hum Genet       Date:  1989-03       Impact factor: 4.132
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