Literature DB >> 32235273

Applications of machine learning methods in kidney disease: hope or hype?

Lili Chan1, Akhil Vaid, Girish N Nadkarni.   

Abstract

PURPOSE OF REVIEW: The universal adoption of electronic health records, improvement in technology, and the availability of continuous monitoring has generated large quantities of healthcare data. Machine learning is increasingly adopted by nephrology researchers to analyze this data in order to improve the care of their patients. RECENT
FINDINGS: In this review, we provide a broad overview of the different types of machine learning algorithms currently available and how researchers have applied these methods in nephrology research. Current applications have included prediction of acute kidney injury and chronic kidney disease along with progression of kidney disease. Researchers have demonstrated the ability of machine learning to read kidney biopsy samples, identify patient outcomes from unstructured data, and identify subtypes in complex diseases. We end with a discussion on the ethics and potential pitfalls of machine learning.
SUMMARY: Machine learning provides researchers with the ability to analyze data that were previously inaccessible. While still burgeoning, several studies show promising results, which will enable researchers to perform larger scale studies and clinicians the ability to provide more personalized care. However, we must ensure that implementation aids providers and does not lead to harm to patients.

Entities:  

Mesh:

Year:  2020        PMID: 32235273      PMCID: PMC7770625          DOI: 10.1097/MNH.0000000000000604

Source DB:  PubMed          Journal:  Curr Opin Nephrol Hypertens        ISSN: 1062-4821            Impact factor:   3.416


  28 in total

1.  Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.

Authors:  Christopher W Seymour; Jason N Kennedy; Shu Wang; Chung-Chou H Chang; Corrine F Elliott; Zhongying Xu; Scott Berry; Gilles Clermont; Gregory Cooper; Hernando Gomez; David T Huang; John A Kellum; Qi Mi; Steven M Opal; Victor Talisa; Tom van der Poll; Shyam Visweswaran; Yoram Vodovotz; Jeremy C Weiss; Donald M Yealy; Sachin Yende; Derek C Angus
Journal:  JAMA       Date:  2019-05-28       Impact factor: 56.272

2.  Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.

Authors:  Emma Ahlqvist; Petter Storm; Annemari Käräjämäki; Mats Martinell; Mozhgan Dorkhan; Annelie Carlsson; Petter Vikman; Rashmi B Prasad; Dina Mansour Aly; Peter Almgren; Ylva Wessman; Nael Shaat; Peter Spégel; Hindrik Mulder; Eero Lindholm; Olle Melander; Ola Hansson; Ulf Malmqvist; Åke Lernmark; Kaj Lahti; Tom Forsén; Tiinamaija Tuomi; Anders H Rosengren; Leif Groop
Journal:  Lancet Diabetes Endocrinol       Date:  2018-03-05       Impact factor: 32.069

3.  Human-level control through deep reinforcement learning.

Authors:  Volodymyr Mnih; Koray Kavukcuoglu; David Silver; Andrei A Rusu; Joel Veness; Marc G Bellemare; Alex Graves; Martin Riedmiller; Andreas K Fidjeland; Georg Ostrovski; Stig Petersen; Charles Beattie; Amir Sadik; Ioannis Antonoglou; Helen King; Dharshan Kumaran; Daan Wierstra; Shane Legg; Demis Hassabis
Journal:  Nature       Date:  2015-02-26       Impact factor: 49.962

4.  Disease progression subtype discovery from longitudinal EMR data with a majority of missing values and unknown initial time points.

Authors:  Ilkka Huopaniemi; Girish Nadkarni; Rajiv Nadukuru; Vaneet Lotay; Steve Ellis; Omri Gottesman; Erwin P Bottinger
Journal:  AMIA Annu Symp Proc       Date:  2014-11-14

5.  Statistical validation of image segmentation quality based on a spatial overlap index.

Authors:  Kelly H Zou; Simon K Warfield; Aditya Bharatha; Clare M C Tempany; Michael R Kaus; Steven J Haker; William M Wells; Ferenc A Jolesz; Ron Kikinis
Journal:  Acad Radiol       Date:  2004-02       Impact factor: 3.173

6.  Unique sex- and age-dependent effects in protective pathways in acute kidney injury.

Authors:  Ravindra Boddu; Chunlan Fan; Sunil Rangarajan; Bhuvana Sunil; Subhashini Bolisetty; Lisa M Curtis
Journal:  Am J Physiol Renal Physiol       Date:  2017-07-05

7.  A call for deep-learning healthcare.

Authors:  Beau Norgeot; Benjamin S Glicksberg; Atul J Butte
Journal:  Nat Med       Date:  2019-01       Impact factor: 53.440

Review 8.  Diabetic kidney disease: world wide difference of prevalence and risk factors.

Authors:  Osama Gheith; Nashwa Farouk; Narayanan Nampoory; Medhat A Halim; Torki Al-Otaibi
Journal:  J Nephropharmacol       Date:  2015-10-09

Review 9.  The digital scribe.

Authors:  Enrico Coiera; Baki Kocaballi; John Halamka; Liliana Laranjo
Journal:  NPJ Digit Med       Date:  2018-10-16

Review 10.  Opportunities and obstacles for deep learning in biology and medicine.

Authors:  Travers Ching; Daniel S Himmelstein; Brett K Beaulieu-Jones; Alexandr A Kalinin; Brian T Do; Gregory P Way; Enrico Ferrero; Paul-Michael Agapow; Michael Zietz; Michael M Hoffman; Wei Xie; Gail L Rosen; Benjamin J Lengerich; Johnny Israeli; Jack Lanchantin; Stephen Woloszynek; Anne E Carpenter; Avanti Shrikumar; Jinbo Xu; Evan M Cofer; Christopher A Lavender; Srinivas C Turaga; Amr M Alexandari; Zhiyong Lu; David J Harris; Dave DeCaprio; Yanjun Qi; Anshul Kundaje; Yifan Peng; Laura K Wiley; Marwin H S Segler; Simina M Boca; S Joshua Swamidass; Austin Huang; Anthony Gitter; Casey S Greene
Journal:  J R Soc Interface       Date:  2018-04       Impact factor: 4.293

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  2 in total

1.  Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.

Authors:  Kumardeep Chaudhary; Akhil Vaid; Áine Duffy; Ishan Paranjpe; Suraj Jaladanki; Manish Paranjpe; Kipp Johnson; Avantee Gokhale; Pattharawin Pattharanitima; Kinsuk Chauhan; Ross O'Hagan; Tielman Van Vleck; Steven G Coca; Richard Cooper; Benjamin Glicksberg; Erwin P Bottinger; Lili Chan; Girish N Nadkarni
Journal:  Clin J Am Soc Nephrol       Date:  2020-10-08       Impact factor: 8.237

2.  Natural Language Processing in Diagnostic Texts from Nephropathology.

Authors:  Maximilian Legnar; Philipp Daumke; Jürgen Hesser; Stefan Porubsky; Zoran Popovic; Jan Niklas Bindzus; Joern-Helge Heinrich Siemoneit; Cleo-Aron Weis
Journal:  Diagnostics (Basel)       Date:  2022-07-15
  2 in total

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