Literature DB >> 31956534

Assessment of lumbar paraspinal muscle activation using fMRI BOLD imaging and T2 mapping.

Yi-Long Huang1, Jia-Long Zhou1,2, Yuan-Ming Jiang1, Zhen-Guang Zhang1, Wei Zhao1, Dan Han1, Bo He1.   

Abstract

BACKGROUND: Our study aimed to investigate the feasibility of functional magnetic resonance imaging [blood oxygen level-dependent (BOLD) imaging and T2 mapping] in monitoring the activation of lumbar paraspinal muscles before and after exercise.
METHODS: The ethics committee of the First Affiliated Hospital of Kunming Medical University approved our study. Both BOLD and T2 mapping of paraspinal muscles were performed in 50 healthy, young volunteers before and after upper-body extension exercises. The movement tasks included upper body flexion and extension using a simple Roman chair. Cross-sectional area (CSA), R2*, and T2 values were measured in various lower-back anatomical regions. The SPSS22.0 statistical software was used to analyze all the data.
RESULTS: Post-exercise CSA and T2 values were higher than those recorded in the pre-exercise session for the three lower-back muscles that were evaluated (iliocostalis, longissimus, and multifidus) (P<0.01). However, R2* values of these muscles were significantly lower after exercise (P<0.01). A significant difference in the R2*, CSA, and T2 values of the iliocostalis occurred between males and females (P<0.05). No statistically significant differences were evident for R2*, CSA, and T2 of the lower-back muscles between L3 and L4 levels, or between the left and right sides. The total CSA of the iliocostalis was higher than that of the multifidus and longissimus (P<0.05).
CONCLUSIONS: BOLD and T2 mapping are feasible non-invasive indirect assessments of lumbar paraspinal muscle activation before and after exercise. 2020 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Entities:  

Keywords:  Blood oxygen level-dependent (BOLD); T2 mapping; cross-sectional area (CSA); functional magnetic resonance imaging (fMRI); muscle activation; paraspinal muscle

Year:  2020        PMID: 31956534      PMCID: PMC6960437          DOI: 10.21037/qims.2019.10.20

Source DB:  PubMed          Journal:  Quant Imaging Med Surg        ISSN: 2223-4306


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