Literature DB >> 31895474

Informed consent, therapeutic misconception, and clinical trials for Alzheimer's disease.

James M Wilkins1,2, Brent P Forester1,2.   

Abstract

Entities:  

Keywords:  Alzheimer's disease; bioethics; clinical trials; informed consent; therapeutics

Year:  2020        PMID： 31895474      PMCID： PMC7141972          DOI： 10.1002/gps.5262

Source DB:  PubMed          Journal:  Int J Geriatr Psychiatry        ISSN： 0885-6230            Impact factor:   3.485


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  43 in total

1.  How do AD patients and their caregivers decide whether to enroll in a clinical trial?

Authors:  J H Karlawish; D Casarett; J Klocinski; P Sankar
Journal:  Neurology       Date:  2001-03-27       Impact factor: 9.910

2.  An approach to evaluating the therapeutic misconception.

Authors:  Scott Y H Kim; Lauren Schrock; Renee M Wilson; Samuel A Frank; Robert G Holloway; Karl Kieburtz; Raymond G de Vries
Journal:  IRB       Date:  2009 Sep-Oct

Review 3.  The Large Pharmaceutical Company Perspective.

Authors:  Michael Rosenblatt
Journal:  N Engl J Med       Date:  2017-01-05       Impact factor: 91.245

4.  Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease.

Authors:  Lawrence S Honig; Bruno Vellas; Michael Woodward; Mercè Boada; Roger Bullock; Michael Borrie; Klaus Hager; Niels Andreasen; Elio Scarpini; Hong Liu-Seifert; Michael Case; Robert A Dean; Ann Hake; Karen Sundell; Vicki Poole Hoffmann; Christopher Carlson; Rashna Khanna; Mark Mintun; Ronald DeMattos; Katherine J Selzler; Eric Siemers
Journal:  N Engl J Med       Date:  2018-01-25       Impact factor: 91.245

5.  When Does Therapeutic Misconception Affect Surrogates' or Subjects' Decision Making about Whether to Participate in Dementia Research?

Authors:  Laura B Dunn; Barton W Palmer
Journal:  AMA J Ethics       Date:  2017-07-01

6.  Why doesn't a family member of a person with advanced dementia use a substituted judgment when making a decision for that person?

Authors:  Karen B Hirschman; Jennifer M Kapo; Jason H T Karlawish
Journal:  Am J Geriatr Psychiatry       Date:  2006-08       Impact factor: 4.105

7.  Public's approach to surrogate consent for dementia research: cautious pragmatism.

Authors:  Raymond De Vries; Kerry A Ryan; Aimee Stanczyk; Paul S Appelbaum; Laura Damschroder; David S Knopman; Scott Y H Kim
Journal:  Am J Geriatr Psychiatry       Date:  2013-01-12       Impact factor: 4.105

8.  Assessment of therapeutic misconception in older schizophrenia patients with a brief instrument.

Authors:  Laura B Dunn; Barton W Palmer; Monique Keehan; Dilip V Jeste; Paul S Appelbaum
Journal:  Am J Psychiatry       Date:  2006-03       Impact factor: 18.112

9.  Alzheimer's disease drug-development pipeline: few candidates, frequent failures.

Authors:  Jeffrey L Cummings; Travis Morstorf; Kate Zhong
Journal:  Alzheimers Res Ther       Date:  2014-07-03       Impact factor: 6.982

10.  Alzheimer's disease drug development pipeline: 2018.

Authors:  Jeffrey Cummings; Garam Lee; Aaron Ritter; Kate Zhong
Journal:  Alzheimers Dement (N Y)       Date:  2018-05-03
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  3 in total

Review 1.  Reconsidering Gold Standards for Surrogate Decision Making for People with Dementia.

Authors:  James M Wilkins
Journal:  Psychiatr Clin North Am       Date:  2021-12

2.  Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners.

Authors:  James M Wilkins; Joseph J Locascio; Jeanette M Gunther; Teresa Gomez-Isla; Bradley T Hyman; Deborah Blacker; Brent P Forester; Olivia I Okereke
Journal:  Int J Geriatr Psychiatry       Date:  2021-09-08       Impact factor: 3.485

3.  Data-driven discovery of probable Alzheimer's disease and related dementia subphenotypes using electronic health records.

Authors:  Jie Xu; Fei Wang; Zhenxing Xu; Prakash Adekkanattu; Pascal Brandt; Guoqian Jiang; Richard C Kiefer; Yuan Luo; Chengsheng Mao; Jennifer A Pacheco; Luke V Rasmussen; Yiye Zhang; Richard Isaacson; Jyotishman Pathak
Journal:  Learn Health Syst       Date:  2020-09-10
  3 in total

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