Literature DB >> 31768354

Perioperative Management of Pancreaticoduodenectomy: Avoiding Admission to the Intensive Care Unit.

Walid Faraj1, Deborah Mukherji2, Ahmad M Zaghal1, Hussein Nassar1, Farah H Mokadem3, Samar Jabbour3, Chakib Ayoub3, Marwan S Rizk3, Mariam Kanso1, Rola F Jaafar1, Nigel Heaton4, Mohamad Khalife1.   

Abstract

INTRODUCTION: With the advancement in surgical expertise at high-volume centers and advances in perioperative management, pancreaticoduodenectomy is becoming safer and remains the gold standard for treating periampullary pathologies. We describe our experience in optimizing perioperative management in order to avoid admission to the intensive care unit and improve outcomes.
METHOD: Retrospective data were collected on 370 surgical patients who underwent a pancreaticoduodenectomy between the years 1994 and 2016.
RESULTS: Of the 370 patients, 200 operated between 2009 and 2016 did not require intensive care admission, blood transfusion, or central line insertion. The results were compared between different time intervals: before the year 1998, between the years 1998 and 2008, and between the years 2009 and 2016. The median blood loss dropped from 800 to 400 to 300 mL, respectively. The median operative time also dropped from 360 to 335 to 215 min, respectively. In addition, the median length of hospital stay decreased from 25 to 16 to 7 days, respectively.
CONCLUSION: With the centralization of pancreaticoduodenectomy in high-volume centers and with specialized surgeons performing the surgery, there is a significant decrease in the onset of postoperative complications with a lesser need for blood transfusions and, subsequently, better recovery of patients without the need for intensive care unit admission.
Copyright © 2019 by S. Karger AG, Basel.

Entities:  

Keywords:  Outcome; Pancreatic cancer; Pancreaticoduodenectomy

Year:  2019        PMID: 31768354      PMCID: PMC6873035          DOI: 10.1159/000502887

Source DB:  PubMed          Journal:  Gastrointest Tumors        ISSN: 2296-3774


  18 in total

1.  Frequency with which surgeons undertake pancreaticoduodenectomy determines length of stay, hospital charges, and in-hospital mortality.

Authors:  A S Rosemurgy; M Bloomston; F M Serafini; B Coon; M M Murr; L C Carey
Journal:  J Gastrointest Surg       Date:  2001 Jan-Feb       Impact factor: 3.452

2.  Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience.

Authors:  C Max Schmidt; Olivier Turrini; Purvi Parikh; Michael G House; Nicholas J Zyromski; Atilla Nakeeb; Thomas J Howard; Henry A Pitt; Keith D Lillemoe
Journal:  Arch Surg       Date:  2010-07

3.  Frequency with which surgeons undertake pancreaticoduodenectomy continues to determine length of stay, hospital charges, and in-hospital mortality.

Authors:  Alexander Rosemurgy; Sarah Cowgill; Brian Coe; Ashley Thomas; Sam Al-Saadi; Steven Goldin; Emmanuel Zervos
Journal:  J Gastrointest Surg       Date:  2007-12-22       Impact factor: 3.452

4.  Pancreaticoduodenectomy at High-volume Centers: Surgeon Volume Goes Beyond the Leapfrog Criteria.

Authors:  Abhishek Mathur; Kenneth Luberice; Sharona Ross; Edward Choung; Alexander Rosemurgy
Journal:  Ann Surg       Date:  2015-08       Impact factor: 12.969

5.  Determinants of pancreaticoenteric anastomotic leak following pancreaticoduodenectomy.

Authors:  S Srivastava; S S Sikora; C M Pandey; A Kumar; R Saxena; V K Kapoor
Journal:  ANZ J Surg       Date:  2001-09       Impact factor: 1.872

6.  Whipple's pancreaticoduodenectomy: Surgical technique and perioperative clinical outcomes in a single center.

Authors:  Giorgio Romano; Antonino Agrusa; Massimo Galia; Giuseppe Di Buono; Daniela Chianetta; Vincenzo Sorce; Leonardo Gulotta; Giuseppe Brancatelli; Gaspare Gulotta
Journal:  Int J Surg       Date:  2015-06-26       Impact factor: 6.071

7.  Effect of hospital volume on in-hospital mortality with pancreaticoduodenectomy.

Authors:  J D Birkmeyer; S R Finlayson; A N Tosteson; S M Sharp; A L Warshaw; E S Fisher
Journal:  Surgery       Date:  1999-03       Impact factor: 3.982

8.  Predictive factors for complications after pancreaticoduodenectomy.

Authors:  Qingbao Cheng; Baihe Zhang; Yongjie Zhang; Xiaoqing Jiang; Baohua Zhang; Bin Yi; Xiangji Luo; Mengchao Wu
Journal:  J Surg Res       Date:  2007-02-08       Impact factor: 2.192

9.  Long-term results of partial pancreaticoduodenectomy for ductal adenocarcinoma of the pancreatic head: 25-year experience.

Authors:  Axel Richter; Marco Niedergethmann; Jörg W Sturm; Dietmar Lorenz; Stefan Post; Michael Trede
Journal:  World J Surg       Date:  2003-02-27       Impact factor: 3.352

Review 10.  Type I interferon-mediated pathway interacts with peroxisome proliferator activated receptor-γ (PPAR-γ): at the cross-road of pancreatic cancer cell proliferation.

Authors:  Alessandra Dicitore; Michele Caraglia; Germano Gaudenzi; Gloria Manfredi; Bruno Amato; Daniela Mari; Luca Persani; Claudio Arra; Giovanni Vitale
Journal:  Biochim Biophys Acta       Date:  2013-12-01
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