Brian N Smith1, Avron Spiro, Susan M Frayne, Rachel Kimerling, Yasmin Cypel, Matthew J Reinhard, Amy M Kilbourne, Kathryn M Magruder. 1. From the National Center for PTSD Women's Health Sciences Division (Smith), VA Boston Healthcare System; Department of Psychiatry (Smith, Spiro), Boston University School of Medicine; Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System (Spiro); Department of Epidemiology (Spiro), Boston University School of Public Health, Boston, Massachusetts; VA HSR&D Center for Innovation to Implementation (Ci2i), VA Palo Alto Health Care System (Frayne, Kimerling), Palo Alto; Division of Primary Care and Population Health (Frayne), Stanford University School of Medicine, Stanford, California; Department of Veterans Affairs, National Center for PTSD (Kimerling), VA Palo Alto Health Care System, Menlo Park, California; US Department of Veterans Affairs, Epidemiology Program, Post Deployment Health Services (10P4Q), Office of Patient Care Services (Cypel); War Related Illness and Injury Study Center, Veteran Affairs Medical Center (Reinhard), Washington, DC; Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan (Kilbourne); Quality Enhancement Research Initiative (QUERI), US Department of Veterans Affairs (Kilbourne), Washington, DC; and Departments of Psychiatry and Behavioral Sciences and Public Health (Magruder), Medical University of South Carolina, Charleston, South Carolina.
Abstract
OBJECTIVE: The effect of stress exposures and mental health sequelae on health-related outcomes is understudied among older women veterans. We examined a) the impact of wartime stress exposures on later-life functioning and disability in Vietnam-era women veterans and b) the extent to which mental health conditions known to be associated with stress-posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and generalized anxiety disorder (GAD)-are associated with additional later-life functioning and disability. METHODS: Data were collected in 2011 to 2012 using a mail survey and telephone interview of 4219 women veterans who were active duty during the Vietnam Era. Health functioning was assessed using the Veterans RAND 36-Item Health Survey, and disability was assessed using the World Health Organization Disability Assessment Schedule 2.0. Wartime exposures were assessed using the Women's War-Zone Stressor Scale-Revised; the Composite International Diagnostic Interview, version 3.0 was used to assess PTSD, MDD, and GAD. RESULTS: Several wartime stress exposures-including job-related pressures, dealing with death, and sexual discrimination and harassment-were associated with worse later-life health (β ranges, -0.04 to -0.26 for functioning, 0.05 to 0.30 for disability). Current PTSD was linked with lower health functioning (physical, β = -0.06; mental, β = -0.15) and greater disability (β = 0.14). Current MDD and GAD were also associated with lower mental health functioning (MDD, β = -0.29; GAD, β = -0.10) and greater disability (MDD, β = 0.16; GAD, β = 0.06). CONCLUSIONS: Results underscore the importance of detection and treatment of the potential long-term effects of wartime stressors and mental health conditions among women veterans.
OBJECTIVE: The effect of stress exposures and mental health sequelae on health-related outcomes is understudied among older women veterans. We examined a) the impact of wartime stress exposures on later-life functioning and disability in Vietnam-era women veterans and b) the extent to which mental health conditions known to be associated with stress-posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and generalized anxiety disorder (GAD)-are associated with additional later-life functioning and disability. METHODS: Data were collected in 2011 to 2012 using a mail survey and telephone interview of 4219 women veterans who were active duty during the Vietnam Era. Health functioning was assessed using the Veterans RAND 36-Item Health Survey, and disability was assessed using the World Health Organization Disability Assessment Schedule 2.0. Wartime exposures were assessed using the Women's War-Zone Stressor Scale-Revised; the Composite International Diagnostic Interview, version 3.0 was used to assess PTSD, MDD, and GAD. RESULTS: Several wartime stress exposures-including job-related pressures, dealing with death, and sexual discrimination and harassment-were associated with worse later-life health (β ranges, -0.04 to -0.26 for functioning, 0.05 to 0.30 for disability). Current PTSD was linked with lower health functioning (physical, β = -0.06; mental, β = -0.15) and greater disability (β = 0.14). Current MDD and GAD were also associated with lower mental health functioning (MDD, β = -0.29; GAD, β = -0.10) and greater disability (MDD, β = 0.16; GAD, β = 0.06). CONCLUSIONS: Results underscore the importance of detection and treatment of the potential long-term effects of wartime stressors and mental health conditions among women veterans.
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