Sarah Graham1,2, Colin Depp1,2,3, Ellen E Lee1,2,3, Camille Nebeker4, Xin Tu1,2, Ho-Cheol Kim5, Dilip V Jeste6,7,8,9. 1. Department of Psychiatry, University of California San Diego, La Jolla, CA, USA. 2. Sam and Rose Stein Institute for Research on Aging, University of California La Jolla, La Jolla, CA, USA. 3. VA San Diego Healthcare System, San Diego, CA, USA. 4. Department of Family Medicine and Public Health, University of California La Jolla, La Jolla, CA, USA. 5. Scalable Knowledge Intelligence, IBM Research-Almaden, San Jose, CA, USA. 6. Department of Psychiatry, University of California San Diego, La Jolla, CA, USA. djeste@ucsd.edu. 7. Sam and Rose Stein Institute for Research on Aging, University of California La Jolla, La Jolla, CA, USA. djeste@ucsd.edu. 8. Department of Neurosciences, University of California La Jolla, La Jolla, CA, USA. djeste@ucsd.edu. 9. University of California San Diego, 9500 Gilman Drive, Mail Code #0664, La Jolla, CA, 92093-0664, USA. djeste@ucsd.edu.
Abstract
PURPOSE OF REVIEW: Artificial intelligence (AI) technology holds both great promise to transform mental healthcare and potential pitfalls. This article provides an overview of AI and current applications in healthcare, a review of recent original research on AI specific to mental health, and a discussion of how AI can supplement clinical practice while considering its current limitations, areas needing additional research, and ethical implications regarding AI technology. RECENT FINDINGS: We reviewed 28 studies of AI and mental health that used electronic health records (EHRs), mood rating scales, brain imaging data, novel monitoring systems (e.g., smartphone, video), and social media platforms to predict, classify, or subgroup mental health illnesses including depression, schizophrenia or other psychiatric illnesses, and suicide ideation and attempts. Collectively, these studies revealed high accuracies and provided excellent examples of AI's potential in mental healthcare, but most should be considered early proof-of-concept works demonstrating the potential of using machine learning (ML) algorithms to address mental health questions, and which types of algorithms yield the best performance. As AI techniques continue to be refined and improved, it will be possible to help mental health practitioners re-define mental illnesses more objectively than currently done in the DSM-5, identify these illnesses at an earlier or prodromal stage when interventions may be more effective, and personalize treatments based on an individual's unique characteristics. However, caution is necessary in order to avoid over-interpreting preliminary results, and more work is required to bridge the gap between AI in mental health research and clinical care.
PURPOSE OF REVIEW: Artificial intelligence (AI) technology holds both great promise to transform mental healthcare and potential pitfalls. This article provides an overview of AI and current applications in healthcare, a review of recent original research on AI specific to mental health, and a discussion of how AI can supplement clinical practice while considering its current limitations, areas needing additional research, and ethical implications regarding AI technology. RECENT FINDINGS: We reviewed 28 studies of AI and mental health that used electronic health records (EHRs), mood rating scales, brain imaging data, novel monitoring systems (e.g., smartphone, video), and social media platforms to predict, classify, or subgroup mental health illnesses including depression, schizophrenia or other psychiatric illnesses, and suicide ideation and attempts. Collectively, these studies revealed high accuracies and provided excellent examples of AI's potential in mental healthcare, but most should be considered early proof-of-concept works demonstrating the potential of using machine learning (ML) algorithms to address mental health questions, and which types of algorithms yield the best performance. As AI techniques continue to be refined and improved, it will be possible to help mental health practitioners re-define mental illnesses more objectively than currently done in the DSM-5, identify these illnesses at an earlier or prodromal stage when interventions may be more effective, and personalize treatments based on an individual's unique characteristics. However, caution is necessary in order to avoid over-interpreting preliminary results, and more work is required to bridge the gap between AI in mental health research and clinical care.
Entities:
Keywords:
Bioethics; Deep learning; Depression; Machine learning; Natural language processing; Research ethics; Schizophrenia; Suicide; Technology
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