Literature DB >> 29989977

Deep EHR: A Survey of Recent Advances in Deep Learning Techniques for Electronic Health Record (EHR) Analysis.

Benjamin Shickel, Patrick James Tighe, Azra Bihorac, Parisa Rashidi.   

Abstract

The past decade has seen an explosion in the amount of digital information stored in electronic health records (EHRs). While primarily designed for archiving patient information and performing administrative healthcare tasks like billing, many researchers have found secondary use of these records for various clinical informatics applications. Over the same period, the machine learning community has seen widespread advances in the field of deep learning. In this review, we survey the current research on applying deep learning to clinical tasks based on EHR data, where we find a variety of deep learning techniques and frameworks being applied to several types of clinical applications including information extraction, representation learning, outcome prediction, phenotyping, and deidentification. We identify several limitations of current research involving topics such as model interpretability, data heterogeneity, and lack of universal benchmarks. We conclude by summarizing the state of the field and identifying avenues of future deep EHR research.

Entities:  

Mesh:

Year:  2017        PMID: 29989977      PMCID: PMC6043423          DOI: 10.1109/JBHI.2017.2767063

Source DB:  PubMed          Journal:  IEEE J Biomed Health Inform        ISSN: 2168-2194            Impact factor:   5.772


  28 in total

1.  Learning vector representation of medical objects via EMR-driven nonnegative restricted Boltzmann machines (eNRBM).

Authors:  Truyen Tran; Tu Dinh Nguyen; Dinh Phung; Svetha Venkatesh
Journal:  J Biomed Inform       Date:  2015-02-03       Impact factor: 6.317

2.  A study of machine-learning-based approaches to extract clinical entities and their assertions from discharge summaries.

Authors:  Min Jiang; Yukun Chen; Mei Liu; S Trent Rosenbloom; Subramani Mani; Joshua C Denny; Hua Xu
Journal:  J Am Med Inform Assoc       Date:  2011-04-20       Impact factor: 4.497

Review 3.  Uses of electronic health records for public health surveillance to advance public health.

Authors:  Guthrie S Birkhead; Michael Klompas; Nirav R Shah
Journal:  Annu Rev Public Health       Date:  2015-01-02       Impact factor: 21.981

Review 4.  Medication-related clinical decision support in computerized provider order entry systems: a review.

Authors:  Gilad J Kuperman; Anne Bobb; Thomas H Payne; Anthony J Avery; Tejal K Gandhi; Gerard Burns; David C Classen; David W Bates
Journal:  J Am Med Inform Assoc       Date:  2006-10-26       Impact factor: 4.497

5.  Predicting Patient's Trajectory of Physiological Data using Temporal Trends in Similar Patients: A System for Near-Term Prognostics.

Authors:  Shahram Ebadollahi; Jimeng Sun; David Gotz; Jianying Hu; Daby Sow; Chalapathy Neti
Journal:  AMIA Annu Symp Proc       Date:  2010-11-13

6.  Combining PubMed knowledge and EHR data to develop a weighted bayesian network for pancreatic cancer prediction.

Authors:  Di Zhao; Chunhua Weng
Journal:  J Biomed Inform       Date:  2011-05-27       Impact factor: 6.317

7.  Using methods from the data-mining and machine-learning literature for disease classification and prediction: a case study examining classification of heart failure subtypes.

Authors:  Peter C Austin; Jack V Tu; Jennifer E Ho; Daniel Levy; Douglas S Lee
Journal:  J Clin Epidemiol       Date:  2013-02-04       Impact factor: 6.437

8.  Named Entity Recognition in Chinese Clinical Text Using Deep Neural Network.

Authors:  Yonghui Wu; Min Jiang; Jianbo Lei; Hua Xu
Journal:  Stud Health Technol Inform       Date:  2015

9.  Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records.

Authors:  Riccardo Miotto; Li Li; Brian A Kidd; Joel T Dudley
Journal:  Sci Rep       Date:  2016-05-17       Impact factor: 4.379

10.  Quality of EHR data extractions for studies of preterm birth in a tertiary care center: guidelines for obtaining reliable data.

Authors:  Lindsey A Knake; Monika Ahuja; Erin L McDonald; Kelli K Ryckman; Nancy Weathers; Todd Burstain; John M Dagle; Jeffrey C Murray; Prakash Nadkarni
Journal:  BMC Pediatr       Date:  2016-04-29       Impact factor: 2.125

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  144 in total

Review 1.  Artificial Intelligence in radiotherapy: state of the art and future directions.

Authors:  Giulio Francolini; Isacco Desideri; Giulia Stocchi; Viola Salvestrini; Lucia Pia Ciccone; Pietro Garlatti; Mauro Loi; Lorenzo Livi
Journal:  Med Oncol       Date:  2020-04-22       Impact factor: 3.064

2.  Extensive phenotype data and machine learning in prediction of mortality in acute coronary syndrome - the MADDEC study.

Authors:  Jussi A Hernesniemi; Shadi Mahdiani; Juho A Tynkkynen; Leo-Pekka Lyytikäinen; Pashupati P Mishra; Terho Lehtimäki; Markku Eskola; Kjell Nikus; Kari Antila; Niku Oksala
Journal:  Ann Med       Date:  2019-04-27       Impact factor: 4.709

Review 3.  Artificial Intelligence for Mental Health and Mental Illnesses: an Overview.

Authors:  Sarah Graham; Colin Depp; Ellen E Lee; Camille Nebeker; Xin Tu; Ho-Cheol Kim; Dilip V Jeste
Journal:  Curr Psychiatry Rep       Date:  2019-11-07       Impact factor: 5.285

4.  Interpretation of machine learning predictions for patient outcomes in electronic health records.

Authors:  William La Cava; Christopher Bauer; Jason H Moore; Sarah A Pendergrass
Journal:  AMIA Annu Symp Proc       Date:  2020-03-04

Review 5.  Impact of Real-World Data on Market Authorization, Reimbursement Decision & Price Negotiation.

Authors:  Alfredo Aram Pulini; Gabriela Martins Caetano; Henri Clautiaux; Laure Vergeron; Peter J Pitts; Gregory Katz
Journal:  Ther Innov Regul Sci       Date:  2020-08-28       Impact factor: 1.778

6.  Machine learning for phenotyping opioid overdose events.

Authors:  Jonathan Badger; Eric LaRose; John Mayer; Fereshteh Bashiri; David Page; Peggy Peissig
Journal:  J Biomed Inform       Date:  2019-04-25       Impact factor: 6.317

Review 7.  Deep learning in clinical natural language processing: a methodical review.

Authors:  Stephen Wu; Kirk Roberts; Surabhi Datta; Jingcheng Du; Zongcheng Ji; Yuqi Si; Sarvesh Soni; Qiong Wang; Qiang Wei; Yang Xiang; Bo Zhao; Hua Xu
Journal:  J Am Med Inform Assoc       Date:  2020-03-01       Impact factor: 4.497

Review 8.  How Machine Learning Will Transform Biomedicine.

Authors:  Jeremy Goecks; Vahid Jalili; Laura M Heiser; Joe W Gray
Journal:  Cell       Date:  2020-04-02       Impact factor: 41.582

9.  A study of generalizability of recurrent neural network-based predictive models for heart failure onset risk using a large and heterogeneous EHR data set.

Authors:  Laila Rasmy; Yonghui Wu; Ningtao Wang; Xin Geng; W Jim Zheng; Fei Wang; Hulin Wu; Hua Xu; Degui Zhi
Journal:  J Biomed Inform       Date:  2018-06-15       Impact factor: 6.317

10.  Deep Learning Prediction of Mild Cognitive Impairment using Electronic Health Records.

Authors:  Sajjad Fouladvand; Michelle M Mielke; Maria Vassilaki; Jennifer St Sauver; Ronald C Petersen; Sunghwan Sohn
Journal:  Proceedings (IEEE Int Conf Bioinformatics Biomed)       Date:  2020-02-06
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