Literature DB >> 3163888

Combined linkage and segregation analysis using regressive models.

G E Bonney1, G M Lathrop, J M Lalouel.   

Abstract

Regressive models for segregation analysis have been extended to include multivariate data and linked marker loci. The new models have been applied to data from two pedigrees segregating a gene for cardiovascular disease.

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Year:  1988        PMID： 3163888      PMCID： PMC1715288     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  10 in total

Review 1.  Statistical modeling and analysis in human genetics.

Authors:  R C Elston; D C Rao
Journal:  Annu Rev Biophys Bioeng       Date:  1978

2.  Sampling considerations in the gathering and analysis of pedigree data.

Authors:  R C Elston; E Sobel
Journal:  Am J Hum Genet       Date:  1979-01       Impact factor: 11.025

3.  Ascertainment in the sequential sampling of pedigrees.

Authors:  C Cannings; E A Thompson
Journal:  Clin Genet       Date:  1977-10       Impact factor: 4.438

4.  Analysis of family resemblance. 3. Complex segregation of quantitative traits.

Authors:  N E Morton; C J MacLean
Journal:  Am J Hum Genet       Date:  1974-07       Impact factor: 11.025

5.  A general model for the genetic analysis of pedigree data.

Authors:  R C Elston; J Stewart
Journal:  Hum Hered       Date:  1971       Impact factor: 0.444

6.  A DNA probe for the LDL receptor gene is tightly linked to hypercholesterolemia in a pedigree with early coronary disease.

Authors:  M F Leppert; S J Hasstedt; T Holm; P O'Connell; L Wu; O Ash; R R Williams; R White
Journal:  Am J Hum Genet       Date:  1986-09       Impact factor: 11.025

7.  A unified model for complex segregation analysis.

Authors:  J M Lalouel; D C Rao; N E Morton; R C Elston
Journal:  Am J Hum Genet       Date:  1983-09       Impact factor: 11.025

8.  On the statistical determination of major gene mechanisms in continuous human traits: regressive models.

Authors:  G E Bonney
Journal:  Am J Med Genet       Date:  1984-08

9.  Strategies for multilocus linkage analysis in humans.

Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

10.  Genetic analysis of von Willebrand's disease in two large pedigrees: a multivariate approach.

Authors:  L R Goldin; R C Elston; J B Graham; C H Miller
Journal:  Am J Med Genet       Date:  1980
  10 in total
  28 in total

1.  Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results.

Authors:  J T Williams; P Van Eerdewegh; L Almasy; J Blangero
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

2.  Maximum likelihood mapping of quantitative trait loci using full-sib families.

Authors:  S A Knott; C S Haley
Journal:  Genetics       Date:  1992-12       Impact factor: 4.562

3.  A Monte Carlo method for combined segregation and linkage analysis.

Authors:  S W Guo; E A Thompson
Journal:  Am J Hum Genet       Date:  1992-11       Impact factor: 11.025

Review 4.  Linkage analysis in the next-generation sequencing era.

Authors:  Joan E Bailey-Wilson; Alexander F Wilson
Journal:  Hum Hered       Date:  2011-12-23       Impact factor: 0.444

5.  Use of the robust sib-pair method to screen for single-locus, multiple-locus, and pleiotropic effects: application to traits related to hypertension.

Authors:  A F Wilson; R C Elston; L D Tran; R M Siervogel
Journal:  Am J Hum Genet       Date:  1991-05       Impact factor: 11.025

6.  Can a susceptibility locus for schizophrenia be excluded from chromosome 5q11-13?

Authors:  C I Amos; M Martinez; S J Bale
Journal:  Am J Hum Genet       Date:  1991-06       Impact factor: 11.025

7.  Interactions between genetic and reproductive factors in breast cancer risk in a French family sample.

Authors:  N Andrieu; F Demenais
Journal:  Am J Hum Genet       Date:  1997-09       Impact factor: 11.025

8.  Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis.

Authors:  E Villard; L Tiret; S Visvikis; R Rakotovao; F Cambien; F Soubrier
Journal:  Am J Hum Genet       Date:  1996-06       Impact factor: 11.025

9.  Sample-size guidelines for linkage analysis of a dominant locus for a quantitative trait by the method of lod scores.

Authors:  M Boehnke
Journal:  Am J Hum Genet       Date:  1990-08       Impact factor: 11.025

10.  A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype.

Authors:  C I Amos; R C Elston; G E Bonney; B J Keats; G S Berenson
Journal:  Am J Hum Genet       Date:  1990-08       Impact factor: 11.025
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