Literature DB >> 31636963

Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor.

Xin Shi1, Jia Shou1, Mohammadreza M Mehryar1, Jingwei Li1, Leyang Wang1, Mo Zhang1, Haiyan Huang1, Xiaofang Sun2, Qiang Wu1,2.   

Abstract

Entities:  

Keywords:  Bioinformatics; DNA recombination

Year:  2019        PMID： 31636963      PMCID： PMC6796948          DOI： 10.1038/s41421-019-0120-z

Source DB:  PubMed          Journal:  Cell Discov        ISSN： 2056-5968            Impact factor:   10.849


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  9 in total

1.  Predictable and precise template-free CRISPR editing of pathogenic variants.

Authors:  Max W Shen; Mandana Arbab; Jonathan Y Hsu; Daniel Worstell; Sannie J Culbertson; Olga Krabbe; Christopher A Cassa; David R Liu; David K Gifford; Richard I Sherwood
Journal:  Nature       Date:  2018-11-07       Impact factor: 49.962

2.  Predicting the mutations generated by repair of Cas9-induced double-strand breaks.

Authors:  Felicity Allen; Luca Crepaldi; Clara Alsinet; Alexander J Strong; Vitalii Kleshchevnikov; Pietro De Angeli; Petra Páleníková; Anton Khodak; Vladimir Kiselev; Michael Kosicki; Andrew R Bassett; Heather Harding; Yaron Galanty; Francisco Muñoz-Martínez; Emmanouil Metzakopian; Stephen P Jackson; Leopold Parts
Journal:  Nat Biotechnol       Date:  2018-11-27       Impact factor: 54.908

3.  Precise and Predictable CRISPR Chromosomal Rearrangements Reveal Principles of Cas9-Mediated Nucleotide Insertion.

Authors:  Jia Shou; Jinhuan Li; Yingbin Liu; Qiang Wu
Journal:  Mol Cell       Date:  2018-07-19       Impact factor: 17.970

Review 4.  CRISPR Double Cutting through the Labyrinthine Architecture of 3D Genomes.

Authors:  Haiyan Huang; Qiang Wu
Journal:  J Genet Genomics       Date:  2016-03-29       Impact factor: 4.275

5.  CRISPR/Cas9 cleavages in budding yeast reveal templated insertions and strand-specific insertion/deletion profiles.

Authors:  Brenda R Lemos; Adam C Kaplan; Ji Eun Bae; Alexander E Ferrazzoli; James Kuo; Ranjith P Anand; David P Waterman; James E Haber
Journal:  Proc Natl Acad Sci U S A       Date:  2018-02-13       Impact factor: 11.205

6.  Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.

Authors:  Beeke Wienert; Stacia K Wyman; Christopher D Richardson; Charles D Yeh; Pinar Akcakaya; Michelle J Porritt; Michaela Morlock; Jonathan T Vu; Katelynn R Kazane; Hannah L Watry; Luke M Judge; Bruce R Conklin; Marcello Maresca; Jacob E Corn
Journal:  Science       Date:  2019-04-18       Impact factor: 47.728

7.  DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells.

Authors:  Clare C So; Alberto Martin
Journal:  PLoS Genet       Date:  2019-04-04       Impact factor: 5.917

8.  Target-Specific Precision of CRISPR-Mediated Genome Editing.

Authors:  Anob M Chakrabarti; Tristan Henser-Brownhill; Josep Monserrat; Anna R Poetsch; Nicholas M Luscombe; Paola Scaffidi
Journal:  Mol Cell       Date:  2018-12-13       Impact factor: 17.970

9.  Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing.

Authors:  Tao Guo; Yi-Li Feng; Jing-Jing Xiao; Qian Liu; Xiu-Na Sun; Ji-Feng Xiang; Na Kong; Si-Cheng Liu; Guo-Qiao Chen; Yue Wang; Meng-Meng Dong; Zhen Cai; Hui Lin; Xiu-Jun Cai; An-Yong Xie
Journal:  Genome Biol       Date:  2018-10-19       Impact factor: 13.583
  9 in total
  8 in total

1.  Cas9-induced large deletions and small indels are controlled in a convergent fashion.

Authors:  Michael Kosicki; Felicity Allen; Frances Steward; Kärt Tomberg; Yangyang Pan; Allan Bradley
Journal:  Nat Commun       Date:  2022-06-14       Impact factor: 17.694

2.  Rational Selection of CRISPR-Cas9 Guide RNAs for Homology-Directed Genome Editing.

Authors:  Kristina J Tatiossian; Robert D E Clark; Chun Huang; Matthew E Thornton; Brendan H Grubbs; Paula M Cannon
Journal:  Mol Ther       Date:  2020-10-14       Impact factor: 11.454

3.  CRISPR/Cas9-mediated mutagenesis at microhomologous regions of human mitochondrial genome.

Authors:  Bang Wang; Xiujuan Lv; Yufei Wang; Zhibo Wang; Qi Liu; Bin Lu; Yong Liu; Feng Gu
Journal:  Sci China Life Sci       Date:  2021-01-06       Impact factor: 6.038

Review 4.  DNA Repair Pathway Choices in CRISPR-Cas9-Mediated Genome Editing.

Authors:  Chaoyou Xue; Eric C Greene
Journal:  Trends Genet       Date:  2021-04-22       Impact factor: 11.821

5.  RGEN-seq for highly sensitive amplification-free screen of off-target sites of gene editors.

Authors:  Alexander Kuzin; Brendan Redler; Jaya Onuska; Alexei Slesarev
Journal:  Sci Rep       Date:  2021-12-08       Impact factor: 4.379

Review 6.  A Curative DNA Code for Hematopoietic Defects: Novel Cell Therapies for Monogenic Diseases of the Blood and Immune System.

Authors:  Matthew H Porteus; Mara Pavel-Dinu; Sung-Yun Pai
Journal:  Hematol Oncol Clin North Am       Date:  2022-06-27       Impact factor: 2.861

7.  Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage.

Authors:  Beomjong Song; Soyeon Yang; Gue-Ho Hwang; Jihyeon Yu; Sangsu Bae
Journal:  Int J Mol Sci       Date:  2021-06-15       Impact factor: 5.923

8.  Targeting DNA polymerase to DNA double-strand breaks reduces DNA deletion size and increases templated insertions generated by CRISPR/Cas9.

Authors:  Kyung W Yoo; Manish Kumar Yadav; Qianqian Song; Anthony Atala; Baisong Lu
Journal:  Nucleic Acids Res       Date:  2022-04-22       Impact factor: 19.160
  8 in total

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