Literature DB >> 31438410

Improving Patient Participation in Cancer Clinical Trials: A Qualitative Analysis of HSRProj & RePORTER.

Lynette Hammond Gerido1, Zhe He1.   

Abstract

Enrollment and representativeness, in cancer trials, have been a problem resulting in studies with poor generalizability to the real-world population. This study uses qualitative analysis of two publicly available datasets (HSRProj and RePORTER) to explore funded research projects, which employ strategies at the macro, meso, and micro levels. Our research shows that although the number of projects designed to increase participation in cancer clinical trials peaked in the 2000s, most employ a single level strategy.

Entities:  

Keywords:  Clinical Trial; Patient Selection; Qualitative Research

Mesh:

Year:  2019        PMID: 31438410      PMCID: PMC6773468          DOI: 10.3233/SHTI190716

Source DB:  PubMed          Journal:  Stud Health Technol Inform        ISSN: 0926-9630


  7 in total

1.  The history of Cancer Research: introducing an AACR Centennial series.

Authors:  I Bernard Weinstein; Kathleen Case
Journal:  Cancer Res       Date:  2008-09-01       Impact factor: 12.701

Review 2.  Quality of life assessments and levels of decision making: differentiating objectives.

Authors:  H J Sutherland; J E Till
Journal:  Qual Life Res       Date:  1993-08       Impact factor: 4.147

3.  Barriers to study enrollment in patients with advanced cancer referred to a phase I clinical trials unit.

Authors:  Siqing Fu; Lacey McQuinn; Aung Naing; Jennifer J Wheler; Filip Janku; Gerald S Falchook; Sarina A Piha-Paul; Dennis Tu; Adrienne Howard; Apostolia Tsimberidou; Ralph Zinner; David S Hong; Razelle Kurzrock
Journal:  Oncologist       Date:  2013-10-23

Review 4.  Strategies addressing barriers to clinical trial enrollment of underrepresented populations: a systematic review.

Authors:  Caren Heller; Joyce E Balls-Berry; Jill Dumbauld Nery; Patricia J Erwin; Dawn Littleton; Mimi Kim; Winston P Kuo
Journal:  Contemp Clin Trials       Date:  2014-08-15       Impact factor: 2.226

5.  An examination of community members', researchers' and health professionals' perceptions of barriers to minority participation in medical research: an application of concept mapping.

Authors:  JaMuir M Robinson; William M K Trochim
Journal:  Ethn Health       Date:  2007-11       Impact factor: 2.772

6.  Clinical trials: the art of enrollment.

Authors:  Claudia R Baquet; Kimberly Henderson; Patricia Commiskey; Jamila N Morrow
Journal:  Semin Oncol Nurs       Date:  2008-11       Impact factor: 2.315

7.  A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results.

Authors:  Tessa Kennedy-Martin; Sarah Curtis; Douglas Faries; Susan Robinson; Joseph Johnston
Journal:  Trials       Date:  2015-11-03       Impact factor: 2.279

  7 in total
  1 in total

Review 1.  Deciding to Enrol in a Cancer Trial: A Systematic Review of Qualitative Studies.

Authors:  Bianca Viljoen; Suzanne K Chambers; Jeff Dunn; Nicholas Ralph; Sonja March
Journal:  J Multidiscip Healthc       Date:  2020-10-27
  1 in total

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