Literature DB >> 19000600

Clinical trials: the art of enrollment.

Claudia R Baquet1, Kimberly Henderson, Patricia Commiskey, Jamila N Morrow.   

Abstract

OBJECTIVES: Enrollment barriers and multidisciplinary approaches to increase cancer trials participation are presented. Recruitment barriers, research in Maryland, and a Best Practice for cancer trials are discussed. DATA SOURCES: Journal and research articles, web sites.
CONCLUSION: Clinical trials have produced prevention and care advances for cancer and other diseases. Trial enrollment is lower for minorities and underserved communities. A comprehensive program for addressing enrollment barriers should incorporate research on barriers, multidisciplinary teams, and education and trial infrastructure in community settings. IMPLICATIONS FOR NURSING PRACTICE: Health disparities training, including culturally appropriate enrollment approaches for education and retention of underserved communities, should incorporate community stakeholders and nurse/physician researchers.

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Year:  2008        PMID: 19000600      PMCID: PMC3262589          DOI: 10.1016/j.soncn.2008.08.006

Source DB:  PubMed          Journal:  Semin Oncol Nurs        ISSN: 0749-2081            Impact factor:   2.315


  16 in total

1.  Recruitment and retention of minority women in cancer screening, prevention, and treatment trials.

Authors:  D R Brown; M N Fouad; K Basen-Engquist; G Tortolero-Luna
Journal:  Ann Epidemiol       Date:  2000-11       Impact factor: 3.797

2.  Maryland's Special Populations Network. A model for cancer disparities research, education, and training.

Authors:  Claudia R Baquet; Kelly M Mack; Shiraz I Mishra; Joy Bramble; Mary Deshields; Delores Datcher; Mervin Savoy; Sandra E Brooks; Stephanie Boykin-Brown; Kery Hummel
Journal:  Cancer       Date:  2006-10-15       Impact factor: 6.860

3.  Recruitment and participation in clinical trials: socio-demographic, rural/urban, and health care access predictors.

Authors:  Claudia R Baquet; Patricia Commiskey; C Daniel Mullins; Shiraz I Mishra
Journal:  Cancer Detect Prev       Date:  2006-02-21

4.  Underrepresentation of patients 65 years of age or older in cancer-treatment trials.

Authors:  L F Hutchins; J M Unger; J J Crowley; C A Coltman; K S Albain
Journal:  N Engl J Med       Date:  1999-12-30       Impact factor: 91.245

5.  A legacy of distrust: African Americans and medical research.

Authors:  V N Gamble
Journal:  Am J Prev Med       Date:  1993 Nov-Dec       Impact factor: 5.043

6.  Participation of patients 65 years of age or older in cancer clinical trials.

Authors:  Joy H Lewis; Meredith L Kilgore; Dana P Goldman; Edward L Trimble; Richard Kaplan; Michael J Montello; Michael G Housman; José J Escarce
Journal:  J Clin Oncol       Date:  2003-04-01       Impact factor: 44.544

7.  How sociodemographics, presence of oncology specialists, and hospital cancer programs affect accrual to cancer treatment trials.

Authors:  Warren B Sateren; Edward L Trimble; Jeffrey Abrams; Otis Brawley; Nancy Breen; Leslie Ford; Mary McCabe; Richard Kaplan; Malcolm Smith; Richard Ungerleider; Michaele C Christian
Journal:  J Clin Oncol       Date:  2002-04-15       Impact factor: 44.544

8.  Public attitudes toward participation in cancer clinical trials.

Authors:  Robert L Comis; Jon D Miller; Carolyn R Aldigé; Linda Krebs; Ellen Stoval
Journal:  J Clin Oncol       Date:  2003-03-01       Impact factor: 44.544

9.  Cancer trial enrollment after state-mandated reimbursement.

Authors:  C P Gross; V Murthy; Y Li; A D Kaluzny; H M Krumholz
Journal:  J Natl Cancer Inst       Date:  2004-07-21       Impact factor: 13.506

10.  Participation in cancer clinical trials: race-, sex-, and age-based disparities.

Authors:  Vivek H Murthy; Harlan M Krumholz; Cary P Gross
Journal:  JAMA       Date:  2004-06-09       Impact factor: 56.272

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  29 in total

1.  Assessing the awareness of and willingness to participate in cancer clinical trials among immigrant Latinos.

Authors:  Sherrie Flynt Wallington; Gheorghe Luta; Anne-Michelle Noone; Larisa Caicedo; Maria Lopez-Class; Vanessa Sheppard; Cherie Spencer; Jeanne Mandelblatt
Journal:  J Community Health       Date:  2012-04

2.  Interest in Research Participation Among Caregivers of Children with Neurodevelopmental Disorders.

Authors:  L Kalb; L Jacobson; C Zisman; E Mahone; R Landa; G Azad; D Menon; V Singh; A Zabel; A Pritchard
Journal:  J Autism Dev Disord       Date:  2019-09

3.  Motivators and barriers to Latinas' participation in clinical trials: the role of contextual factors.

Authors:  Laricca London; Alejandra Hurtado-de-Mendoza; Minna Song; Ankita Nagirimadugu; Gheorghe Luta; Vanessa B Sheppard
Journal:  Contemp Clin Trials       Date:  2014-11-26       Impact factor: 2.226

4.  Minority participation in a school-based randomized clinical trial of tooth decay prevention in the United States.

Authors:  Suchitra Nelson; Peter Milgrom
Journal:  Contemp Clin Trials       Date:  2011-10-01       Impact factor: 2.226

5.  Challenges and potential solutions to meeting accrual goals in a Phase II chemoprevention trial for prostate cancer.

Authors:  Nagi Kumar; Theresa Crocker; Tiffany Smith; Julio Pow-Sang; Philippe E Spiess; Kathleen Egan; Gwen Quinn; Michael Schell; Said Sebti; Aslam Kazi; Tian Chuang; Raoul Salup; Mohamed Helal; Gregory Zagaja; Edouard Trabulsi; Jerry McLarty; Tajammul Fazili; Christopher R Williams; Fred Schreiber; Joel Slaton; J Kyle Anderson
Journal:  Contemp Clin Trials       Date:  2011-11-11       Impact factor: 2.226

6.  Nine key functions for a human subjects protection program for community-engaged research: points to consider.

Authors:  Lainie Friedman Ross; Allan Loup; Robert M Nelson; Jeffrey R Botkin; Rhonda Kost; George R Smith; Sarah Gehlert
Journal:  J Empir Res Hum Res Ethics       Date:  2010-03       Impact factor: 1.742

7.  Development and impact of an intervention to boost recruitment in a multicenter pediatric randomized clinical trial.

Authors:  Sonika Bhatnagar; Alejandro Hoberman; Diana H Kearney; Nader Shaikh; Marva M Moxey-Mims; Russell W Chesney; Myra A Carpenter; Saul P Greenfield; Ron Keren; Tej K Mattoo; Ranjiv Mathews; Lisa Gravens-Mueller; Anastasia Ivanova
Journal:  Clin Pediatr (Phila)       Date:  2013-10-22       Impact factor: 1.168

Review 8.  Strategies addressing barriers to clinical trial enrollment of underrepresented populations: a systematic review.

Authors:  Caren Heller; Joyce E Balls-Berry; Jill Dumbauld Nery; Patricia J Erwin; Dawn Littleton; Mimi Kim; Winston P Kuo
Journal:  Contemp Clin Trials       Date:  2014-08-15       Impact factor: 2.226

9.  Eliminating Racial/Ethnic Disparities in AIDS Clinical Trials in the United States: A Qualitative Exploration of an Efficacious Social/Behavioral Intervention.

Authors:  Amanda Ritchie; Marya Viorst Gwadz; David Perlman; Rebecca De Guzman; Noelle R Leonard; Charles M Cleland
Journal:  J AIDS Clin Res       Date:  2016-12-29

10.  Patient Navigation As a Model to Increase Participation of African Americans in Cancer Clinical Trials.

Authors:  Mona N Fouad; Aras Acemgil; Sejong Bae; Andres Forero; Nedra Lisovicz; Michelle Y Martin; Gabriela R Oates; Edward E Partridge; Selwyn M Vickers
Journal:  J Oncol Pract       Date:  2016-05-17       Impact factor: 3.840

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