An Advanced 100-Channel Readout System for Nuclear Imaging.

Reading out from large-scale silicon photomultiplier (SiPM) arrays is a fundamental technical obstacle blocking the application of revolutionary SiPM technologies in nuclear imaging systems. Typically, it requires using dedicated application-specific integrated circuits (ASICs) that need a long iterative process, special expertise, and tools to develop. The pico-positron emission tomography (Pico-PET) electronics system is an advanced 100-channel readout system based on 1-bit sigma-delta modulation and a field-programmable gate array (FPGA). It is compact (6 × 6 × 0.8 cm3 in size), consumes little power (less than 3W), and is constructed with off-the-shelf low-cost components. In experimental studies, the Pico-PET system demonstrates excellent and consistent performance. In addition, it has some unique features that are essential for nuclear imaging systems, such as its ability to measure V-I curves, breakdown voltages, and the dark currents of 100 SiPMs accurately, simultaneously, and in real time. The flexibility afforded by FPGAs allows multiple-channel clustering and intelligent triggering for different detector designs. These highly sought-after features are not offered by any other ASICs and electronics systems developed for nuclear imaging. We conclude that the Pico-PET electronics system provides a practical solution to the long-standing bottleneck problem that has limited the development of potentially advanced nuclear imaging technology using SiPMs.