Literature DB >> 31300623

Electronics method to advance the coincidence time resolution with bismuth germanate.

Joshua W Cates1, Craig S Levin.   

Abstract

Exploiting the moderate Cherenkov yield from 511 keV photoelectric interactions in bismuth germanate (BGO) scintillators enables one to achieve a level of coincidence time resolution (CTR) appropriate for time-of-flight positron emission tomography (TOF-PET). For this approach, owing to the low number of promptly emitted light photons, single photon time resolution (SPTR) can have a stronger influence on achievable CTR. We have previously shown readout techniques that reduce effective device capacitance of large area silicon photomultipliers (SiPMs) can yield improvements in single photon response shape that minimize the influence of electronic noise on SPTR. With these techniques, sub-100 ps FWHM SPTR can be achieved with [Formula: see text] mm2 FBK near-ultra-violet high density (NUV-HD) SiPMs. These sensors are also useful for detecting Cherenkov light due to relatively high photon detection efficiency for UV light. In this work, we measured CTR for BGO crystals coupled to FBK NUV-HD SiPMs with a passive bootstrapping readout circuit that effectively reduces the SiPM device capacitance. A range of CTR values between 200 [Formula: see text] 3 and 277 [Formula: see text] 7 ps FWHM were measured for 3 [Formula: see text] 3 [Formula: see text] 3 and 3 [Formula: see text] 3 [Formula: see text] 15 mm3 crystals, respectively. This readout technique provides a relatively simple approach to achieve state-of-the-art CTR performance using BGO crystals for TOF-PET.

Entities:  

Mesh:

Substances:

Year:  2019        PMID: 31300623      PMCID: PMC7173328          DOI: 10.1088/1361-6560/ab31e3

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  11 in total

Review 1.  From PET detectors to PET scanners.

Authors:  John L Humm; Anatoly Rosenfeld; Alberto Del Guerra
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-10-02       Impact factor: 9.236

2.  LaBr(3):Ce and SiPMs for time-of-flight PET: achieving 100 ps coincidence resolving time.

Authors:  Dennis R Schaart; Stefan Seifert; Ruud Vinke; Herman T van Dam; Peter Dendooven; Herbert Löhner; Freek J Beekman
Journal:  Phys Med Biol       Date:  2010-03-19       Impact factor: 3.609

3.  Analytical calculation of the lower bound on timing resolution for PET scintillation detectors comprising high-aspect-ratio crystal elements.

Authors:  Joshua W Cates; Ruud Vinke; Craig S Levin
Journal:  Phys Med Biol       Date:  2015-06-17       Impact factor: 3.609

4.  Studies of a Next-Generation Silicon-Photomultiplier-Based Time-of-Flight PET/CT System.

Authors:  David F C Hsu; Ezgi Ilan; William T Peterson; Jorge Uribe; Mark Lubberink; Craig S Levin
Journal:  J Nucl Med       Date:  2017-04-27       Impact factor: 10.057

5.  BGO as a hybrid scintillator / Cherenkov radiator for cost-effective time-of-flight PET.

Authors:  S E Brunner; D R Schaart
Journal:  Phys Med Biol       Date:  2017-03-30       Impact factor: 3.609

6.  Measurement of intrinsic rise times for various L(Y)SO and LuAG scintillators with a general study of prompt photons to achieve 10 ps in TOF-PET.

Authors:  Stefan Gundacker; Etiennette Auffray; Kristof Pauwels; Paul Lecoq
Journal:  Phys Med Biol       Date:  2016-03-16       Impact factor: 3.609

7.  Evaluation of a clinical TOF-PET detector design that achieves ⩽100 ps coincidence time resolution.

Authors:  Joshua W Cates; Craig S Levin
Journal:  Phys Med Biol       Date:  2018-06-07       Impact factor: 3.609

Review 8.  Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care.

Authors:  Simon R Cherry; Terry Jones; Joel S Karp; Jinyi Qi; William W Moses; Ramsey D Badawi
Journal:  J Nucl Med       Date:  2017-09-21       Impact factor: 10.057

9.  Improved single photon time resolution for analog SiPMs with front end readout that reduces influence of electronic noise.

Authors:  Joshua W Cates; Stefan Gundacker; Etiennette Auffray; Paul Lecoq; Craig S Levin
Journal:  Phys Med Biol       Date:  2018-09-19       Impact factor: 3.609

10.  Advances in coincidence time resolution for PET.

Authors:  Joshua W Cates; Craig S Levin
Journal:  Phys Med Biol       Date:  2016-02-25       Impact factor: 3.609

View more
  8 in total

Review 1.  Photon counting detectors and their applications ranging from particle physics experiments to environmental radiation monitoring and medical imaging.

Authors:  Ryosuke Ota
Journal:  Radiol Phys Technol       Date:  2021-03-19

2.  Study of Čerenkov Light Emission in the Semiconductors TlBr and TlCl for TOF-PET.

Authors:  Gerard Ariño-Estrada; Emilie Roncali; Aaron R Selfridge; Junwei Du; Jaroslaw Glodo; Kanai S Shah; Simon R Cherry
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2020-09-17

3.  Integration of polarization in the LUTDavis model for optical Monte Carlo simulation in radiation detectors.

Authors:  Carlotta Trigila; Emilie Roncali
Journal:  Phys Med Biol       Date:  2021-10-22       Impact factor: 4.174

4.  Further investigations of a radiation detector based on ionization-induced modulation of optical polarization.

Authors:  Yuli Wang; Li Tao; Shiva Abbaszadeh; Craig Levin
Journal:  Phys Med Biol       Date:  2021-02-20       Impact factor: 3.609

Review 5.  Silicon photomultiplier signal readout and multiplexing techniques for positron emission tomography: a review.

Authors:  Haewook Park; Minseok Yi; Jae Sung Lee
Journal:  Biomed Eng Lett       Date:  2022-07-16

6.  First-principles studies of defect behaviour in bismuth germanate.

Authors:  Salawu Omotayo Akande; Othmane Bouhali
Journal:  Sci Rep       Date:  2022-09-21       Impact factor: 4.996

7.  A digital phoswich detector using time-over-threshold for depth of interaction in PET.

Authors:  David L Prout; Zheng Gu; Max Shustef; Arion F Chatziioannou
Journal:  Phys Med Biol       Date:  2020-12-15       Impact factor: 3.609

8.  Use of non-Gaussian time-of-flight kernels for image reconstruction of Monte Carlo simulated data of ultra-fast PET scanners.

Authors:  Nikos Efthimiou; Kris Thielemans; Elise Emond; Chris Cawthorne; Stephen J Archibald; Charalampos Tsoumpas
Journal:  EJNMMI Phys       Date:  2020-06-19
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.