INTRODUCTION: The aim of this study was to assess whether early discharge could be non-inferior to inpatient management in selected patients with low-grade renal trauma (AAST grades 1-3). MATERIALS AND METHODS: A retrospective national multicenter study was conducted including all patients who presented with renal trauma at 17 hospitals between 2005 and 2015. Exclusion criteria were iatrogenic and AAST grades 4 and 5 trauma, non-conservative initial management, Hb < 10 g/dl or transfusion within the first 24 h, and patients with concomitant injuries. Patients were divided into two groups according to the length of hospital stay: ≤ 48 h (early discharge), and > 48 h (inpatient). The primary outcome was "Intervention" defined as any interventional procedure needed within the first 30 days. A Stabilized Inverse Probability of Treatment Weighting (SIPTW) propensity score based binary response model was used to estimate risk difference. RESULTS: Out of 1764 patients with renal trauma, 311 were included in the analysis (44 in the early discharge and 267 in the inpatient group). In the early discharge group, only one patient required an intervention within the first 30 days vs. 10 in the inpatient group (3.7% vs. 5.2%; p = 0.99). Adjusted analysis using SIPTW propensity score showed a risk difference of - 2.8% [- 9.3% to + 3.7%] of "interventions" between the two groups meeting the non-inferiority criteria. CONCLUSION: In a highly selected cohort, early discharge management of low-grade renal trauma was not associated with an increased risk of early "intervention" compared to inpatient management. Further prospective randomized controlled trials are needed to confirm these findings.
INTRODUCTION: The aim of this study was to assess whether early discharge could be non-inferior to inpatient management in selected patients with low-grade renal trauma (AAST grades 1-3). MATERIALS AND METHODS: A retrospective national multicenter study was conducted including all patients who presented with renal trauma at 17 hospitals between 2005 and 2015. Exclusion criteria were iatrogenic and AAST grades 4 and 5 trauma, non-conservative initial management, Hb < 10 g/dl or transfusion within the first 24 h, and patients with concomitant injuries. Patients were divided into two groups according to the length of hospital stay: ≤ 48 h (early discharge), and > 48 h (inpatient). The primary outcome was "Intervention" defined as any interventional procedure needed within the first 30 days. A Stabilized Inverse Probability of Treatment Weighting (SIPTW) propensity score based binary response model was used to estimate risk difference. RESULTS: Out of 1764 patients with renal trauma, 311 were included in the analysis (44 in the early discharge and 267 in the inpatient group). In the early discharge group, only one patient required an intervention within the first 30 days vs. 10 in the inpatient group (3.7% vs. 5.2%; p = 0.99). Adjusted analysis using SIPTW propensity score showed a risk difference of - 2.8% [- 9.3% to + 3.7%] of "interventions" between the two groups meeting the non-inferiority criteria. CONCLUSION: In a highly selected cohort, early discharge management of low-grade renal trauma was not associated with an increased risk of early "intervention" compared to inpatient management. Further prospective randomized controlled trials are needed to confirm these findings.
Authors: Allen F Morey; Steve Brandes; Daniel David Dugi; John H Armstrong; Benjamin N Breyer; Joshua A Broghammer; Bradley A Erickson; Jeff Holzbeierlein; Steven J Hudak; Jeffrey H Pruitt; James T Reston; Richard A Santucci; Thomas G Smith; Hunter Wessells Journal: J Urol Date: 2014-05-20 Impact factor: 7.450
Authors: Arash Mahajerin; Brian R Branchford; Ernest K Amankwah; Leslie Raffini; Elizabeth Chalmers; C Heleen van Ommen; Neil A Goldenberg Journal: Haematologica Date: 2015-05-22 Impact factor: 9.941
Authors: Sorena Keihani; Yizhe Xu; Angela P Presson; James M Hotaling; Raminder Nirula; Joshua Piotrowski; Christopher M Dodgion; Cullen M Black; Kaushik Mukherjee; Bradley J Morris; Sarah Majercik; Brian P Smith; Ian Schwartz; Sean P Elliott; Erik S DeSoucy; Scott Zakaluzny; Peter B Thomsen; Bradley A Erickson; Nima Baradaran; Benjamin N Breyer; Brandi Miller; Richard A Santucci; Matthew M Carrick; Timothy Hewitt; Frank N Burks; Jurek F Kocik; Reza Askari; Jeremy B Myers Journal: J Trauma Acute Care Surg Date: 2018-03 Impact factor: 3.313
Authors: Gwendolyn M van der Wilden; George C Velmahos; D'Andrea K Joseph; Lenworth Jacobs; M George Debusk; Charles A Adams; Ronald Gross; Barbara Burkott; Suresh Agarwal; Adrian A Maung; Dirk C Johnson; Jonathan Gates; Edward Kelly; Yvonne Michaud; William E Charash; Robert J Winchell; Steven E Desjardins; Michael S Rosenblatt; Sanjay Gupta; Miguel Gaeta; Yuchiao Chang; Marc A de Moya Journal: JAMA Surg Date: 2013-10 Impact factor: 14.766