Literature DB >> 3118211

Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.

T Alber1, D P Sun, K Wilson, J A Wozniak, S P Cook, B W Matthews.   

Abstract

Measurements of changes in structure and stability caused by 13 different substitutions for threonine 157 in phage T4 lysozyme show that the most stable lysozyme variants contain hydrogen bonds analogous to those in the wild-type enzyme and that structural adjustments allow the protein to be surprisingly tolerant of amino-acid substitutions.

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Year:  1987        PMID： 3118211     DOI： 10.1038/330041a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  44 in total

1.  A test of proposed rules for helix capping: implications for protein design.

Authors:  Martin Sagermann; Lars-Göran Mårtensson; Walter A Baase; Brian W Matthews
Journal:  Protein Sci       Date:  2002-03       Impact factor: 6.725

2.  Use of surface area computations to describe atom-atom interactions.

Authors:  X de La Cruz; M Calvo
Journal:  J Comput Aided Mol Des       Date:  2001-06       Impact factor: 3.686

3.  MoViES: molecular vibrations evaluation server for analysis of fluctuational dynamics of proteins and nucleic acids.

Authors:  Z W Cao; Y Xue; L Y Han; B Xie; H Zhou; C J Zheng; H H Lin; Y Z Chen
Journal:  Nucleic Acids Res       Date:  2004-07-01       Impact factor: 16.971

Review 4.  Protein folding.

Authors:  T E Creighton
Journal:  Biochem J       Date:  1990-08-15       Impact factor: 3.857

5.  Electrostatic fields in the active sites of lysozymes.

Authors:  D P Sun; D I Liao; S J Remington
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

Review 6.  Stability of protein pharmaceuticals.

Authors:  M C Manning; K Patel; R T Borchardt
Journal:  Pharm Res       Date:  1989-11       Impact factor: 4.200

7.  S434F in NrdE generates the thermosensitive phenotype of corynebacterium ammoniagenes CH31 and enhances thermolability by increasing the surface hydrophobicity of the NrdE(Ts) protein.

Authors:  Hesham M Elhariry; Jochen Meens; Matthias Stehr; Georg Auling
Journal:  Appl Environ Microbiol       Date:  2005-09       Impact factor: 4.792

8.  Prediction of protein thermostability with a direction- and distance-dependent knowledge-based potential.

Authors:  Christian Hoppe; Dietmar Schomburg
Journal:  Protein Sci       Date:  2005-09-09       Impact factor: 6.725

9.  Determination by systematic deletion of the amino acids essential for catalysis by ricin A chain.

Authors:  K N Morris; I G Wool
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-01       Impact factor: 11.205

10.  Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A.

Authors:  Daohua Jiang; Yan Zhao; Xianping Wang; Junping Fan; Jie Heng; Xuehui Liu; Wei Feng; Xusheng Kang; Bo Huang; Jianfeng Liu; Xuejun Cai Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-15       Impact factor: 11.205
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