Daisuke Tsurumaru1, Yusuke Nishimuta2, Toshio Muraki2, Yoshiki Asayama3, Akihiro Nishie2, Eiji Oki4, Hiroshi Honda2. 1. Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan. tsuru-d@radiol.med.kyushu-u.ac.jp. 2. Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan. 3. Department of Advanced Imaging and Interventional Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. 4. Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Abstract
PURPOSE: Wall-carving technique (WC) is a special volume rendering technique of three-dimensional CT gastrography that can illustrate the enhancement of gastric wall at an arbitrary depth. We conducted the present study to evaluate the impact of contrast enhancement based on layer depth on WC of gastric cancer and to correlate them with pathological findings. METHODS: The subjects of this retrospective study consisted of 36 patients with advanced gastric cancer (22 men, 14 women; age range, 39-90 years; median, 67 years) who underwent contrast-enhanced CT before surgery. WC images of arterial phase were divided into first and second layer. Two radiologists in consensus evaluated the contrast enhancement of WC images for each layer and correlated with pathologic factors. RESULTS: Twenty-six (72%) of the gastric cancers showed a well-enhanced lesion in the first layer at the arterial phase on WC images, and 18 (50%) showed a well-enhanced lesion in the second layer. The study of second layers showed that the well-enhanced group had significantly more cases of differentiated type histology and intermediate stroma than the normally to poorly enhanced group (p = 0.008 and 0.0026). CONCLUSION: The contrast enhancement on WC of gastric cancer showed a significant relationship with pathological factors based on layer depth.
PURPOSE: Wall-carving technique (WC) is a special volume rendering technique of three-dimensional CT gastrography that can illustrate the enhancement of gastric wall at an arbitrary depth. We conducted the present study to evaluate the impact of contrast enhancement based on layer depth on WC of gastric cancer and to correlate them with pathological findings. METHODS: The subjects of this retrospective study consisted of 36 patients with advanced gastric cancer (22 men, 14 women; age range, 39-90 years; median, 67 years) who underwent contrast-enhanced CT before surgery. WC images of arterial phase were divided into first and second layer. Two radiologists in consensus evaluated the contrast enhancement of WC images for each layer and correlated with pathologic factors. RESULTS: Twenty-six (72%) of the gastric cancers showed a well-enhanced lesion in the first layer at the arterial phase on WC images, and 18 (50%) showed a well-enhanced lesion in the second layer. The study of second layers showed that the well-enhanced group had significantly more cases of differentiated type histology and intermediate stroma than the normally to poorly enhanced group (p = 0.008 and 0.0026). CONCLUSION: The contrast enhancement on WC of gastric cancer showed a significant relationship with pathological factors based on layer depth.
Authors: Da Xu; Rong Liu; Huiping Xu; Zhijian Zhang; Wei Li; Yi Zhang; Wenjun Zhang Journal: Comput Math Methods Med Date: 2022-04-30 Impact factor: 2.238