Literature DB >> 31080604

Time to endoscopy for acute upper gastrointestinal bleeding: Results from a prospective multicentre trainee-led audit.

Keith Siau1,2, James Hodson3, Richard Ingram4, Andrew Baxter4, Monika M Widlak2, Caroline Sharratt4, Graham M Baker2, Tom Troth2, Ben Hicken2, Faraz Tahir2, Malik Magrabi2, Nouman Yousaf2, Claire Grant4, Dennis Poon4, Hesham Khalil4, Hui Lin Lee4, Jonathan R White4, Huey Tan4, Syazeddy Samani4, Patricia Hooper4, Saeed Ahmed4, Muhammad Amin4, Sara Mahgoub2, Khayal Asghar2, Farique Leet2, Matthew J Harborne2, Beata Polewiczowska2, Sheeba Khan2, Muhammad R Anjum2, Michael McFarlane2, Ella Mozdiak2, Lauren D O'Flynn2, Ilona C Blee2, Rachel M Molyneux2, Ashok Kurian2, Syed N Abbas2, Abdullah Abbasi2, Aadil Karim2, Asif Yasin2, Fawad Khattak2, Josephine White2, Ruhina Ahmed2, James A Morgan2, Lance Alleyne2, Mohamed A Alam4, Naaventhan Palaniyappan4, Victoria J Rodger4, Paramvir Sawhney4, Nasar Aslam4, Theodore Okeke4, Adam Lawson4, Danny Cheung2, Jeremy P Reid2, Ashish Awasthi2, Mark R Anderson2, Joe R Timothy2, Sanjeev Pattni4, Saqib Ahmad4, Gillian Townson2, Jeremy Shearman2, Vanja Giljaca2, Matthew J Brookes2, Ben R Disney2, Neil Guha4, Titus Thomas4, Anthony Norman4, Peter Wurm4, Ashit Shah2, Neil C Fisher2, Sauid Ishaq2, Giles Major4.   

Abstract

Background: Endoscopy within 24 h of admission (early endoscopy) is a quality standard in acute upper gastrointestinal bleeding (AUGIB). We aimed to audit time to endoscopy outcomes and identify factors affecting delayed endoscopy (>24 h of admission).
Methods: This prospective multicentre audit enrolled patients admitted with AUGIB who underwent inpatient endoscopy between November and December 2017. Analyses were performed to identify factors associated with delayed endoscopy, and to compare patient outcomes, including length of stay and mortality rates, between early and delayed endoscopy groups.
Results: Across 348 patients from 20 centres, the median time to endoscopy was 21.2 h (IQR 12.0-35.7), comprising median admission to referral and referral to endoscopy times of 8.1 h (IQR 3.7-18.1) and 6.7 h (IQR 3.0-23.1), respectively. Early endoscopy was achieved in 58.9%, although this varied by centre (range: 31.0-87.5%, p = 0.002). On multivariable analysis, lower Glasgow-Blatchford score, delayed referral, admissions between 7:00 and 19:00 hours or via the emergency department were independent predictors of delayed endoscopy. Early endoscopy was associated with reduced length of stay (median difference 1 d; p = 0.004), but not 30-d mortality (p = 0.344). Conclusions: The majority of centres did not meet national standards for time to endoscopy. Strategic initiatives involving acute care services may be necessary to improve this outcome.

Entities:  

Keywords:  Upper gastrointestinal bleeding; endoscopy; haemorrhage; quality; time to endoscopy

Year:  2018        PMID: 31080604      PMCID: PMC6498807          DOI: 10.1177/2050640618811491

Source DB:  PubMed          Journal:  United European Gastroenterol J        ISSN: 2050-6406            Impact factor:   4.623


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