Literature DB >> 3099172

DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae.

P A Silver, R Brent, M Ptashne.   

Abstract

We showed by immunofluorescence that the procaryotic DNA-binding protein LexA and a chimeric protein that contains the DNA-binding portion of LexA (amino acids 1 to 87) and a large portion (amino acids 74 to 881) of the Saccharomyces cerevisiae positive regulatory GAL4 protein (GAL4 gene product) are not preferentially localized in the nucleus in S. cerevisiae.

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Year:  1986        PMID： 3099172      PMCID： PMC367265          DOI： 10.1128/mcb.6.12.4763-4766.1986

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  17 in total

1.  ZINC, A COMPONENT OF YEAST ALCOHOL DEHYDROGENASE.

Authors:  B L Vallee; F L Hoch
Journal:  Proc Natl Acad Sci U S A       Date:  1955-06-15       Impact factor: 11.205

2.  Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein.

Authors:  L Keegan; G Gill; M Ptashne
Journal:  Science       Date:  1986-02-14       Impact factor: 47.728

3.  Nuclear location signals in polyoma virus large-T.

Authors:  W D Richardson; B L Roberts; A E Smith
Journal:  Cell       Date:  1986-01-17       Impact factor: 41.582

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

Review 5.  Repression of transcription in yeast.

Authors:  R Brent
Journal:  Cell       Date:  1985-08       Impact factor: 41.582

6.  A short amino acid sequence able to specify nuclear location.

Authors:  D Kalderon; B L Roberts; W D Richardson; A E Smith
Journal:  Cell       Date:  1984-12       Impact factor: 41.582

7.  A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene.

Authors:  R Brent; M Ptashne
Journal:  Nature       Date:  1984 Dec 13-19       Impact factor: 49.962

8.  Targeting of E. coli beta-galactosidase to the nucleus in yeast.

Authors:  M N Hall; L Hereford; I Herskowitz
Journal:  Cell       Date:  1984-04       Impact factor: 41.582

9.  A polypeptide domain that specifies migration of nucleoplasmin into the nucleus.

Authors:  C Dingwall; S V Sharnick; R A Laskey
Journal:  Cell       Date:  1982-09       Impact factor: 41.582

10.  The abnormal location of cytoplasmic SV40 large T is not caused by failure to bind to DNA or to p53.

Authors:  E Paucha; D Kalderon; W D Richardson; R W Harvey; A E Smith
Journal:  EMBO J       Date:  1985-12-01       Impact factor: 11.598
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  15 in total

1.  Targeted modification and transportation of cellular proteins.

Authors:  P Colas; B Cohen; P Ko Ferrigno; P A Silver; R Brent
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-05       Impact factor: 11.205

2.  vRel is an inactive member of the Rel family of transcriptional activating proteins.

Authors:  P M Richardson; T D Gilmore
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

3.  Inefficient expression of the DNA-binding domain of GAL4 in transgenic plants.

Authors:  C Reichel; D Feltkamp; R Walden; H H Steinbiß; J Schell; S Rosahl
Journal:  Plant Cell Rep       Date:  1995-10       Impact factor: 4.570

4.  Functional eukaryotic nuclear localization signals are widespread in terminal proteins of bacteriophages.

Authors:  Modesto Redrejo-Rodríguez; Daniel Muñoz-Espín; Isabel Holguera; Mario Mencía; Margarita Salas
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-22       Impact factor: 11.205

Review 5.  A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae.

Authors:  M Johnston
Journal:  Microbiol Rev       Date:  1987-12

6.  Amino acid sequences that determine the nuclear localization of yeast histone 2B.

Authors:  R B Moreland; G L Langevin; R H Singer; R L Garcea; L M Hereford
Journal:  Mol Cell Biol       Date:  1987-11       Impact factor: 4.272

7.  Interactions of a Rel protein with its inhibitor.

Authors:  N Lehming; S McGuire; J M Brickman; M Ptashne
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205

Review 8.  Transcriptional regulation in Saccharomyces cerevisiae: transcription factor regulation and function, mechanisms of initiation, and roles of activators and coactivators.

Authors:  Steven Hahn; Elton T Young
Journal:  Genetics       Date:  2011-11       Impact factor: 4.562

Review 9.  Protein transport and compartmentation in yeast.

Authors:  J Horák
Journal:  Folia Microbiol (Praha)       Date:  1991       Impact factor: 2.099

10.  Development of a high-throughput method for the systematic identification of human proteins nuclear translocation potential.

Authors:  Trinh Xuan Hoat; Nicolas Bertin; Noriko Ninomiya; Shiro Fukuda; Kengo Usui; Jun Kawai; Yoshihide Hayashizaki; Harukazu Suzuki
Journal:  BMC Cell Biol       Date:  2009-09-22       Impact factor: 4.241
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