Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete.

Literature DB >> 30982060

How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete.

Laramie E Duncan¹, Michael Ostacher^2,3, Jacob Ballon².

Abstract

Mesh：

Year: 2019 PMID： 30982060 PMCID： PMC6785091 DOI： 10.1038/s41386-019-0389-5

Source DB: PubMed Journal: Neuropsychopharmacology ISSN： 0893-133X Impact factor: 7.853

× No keyword cloud information.

44 in total

Review 1. Problems of reporting genetic associations with complex outcomes.

Authors: Helen M Colhoun; Paul M McKeigue; George Davey Smith
Journal: Lancet Date: 2003-03-08 Impact factor: 79.321

Review 2. Five years of GWAS discovery.

Authors: Peter M Visscher; Matthew A Brown; Mark I McCarthy; Jian Yang
Journal: Am J Hum Genet Date: 2012-01-13 Impact factor: 11.025

3. No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes.

Authors: Emma C Johnson; Richard Border; Whitney E Melroy-Greif; Christiaan A de Leeuw; Marissa A Ehringer; Matthew C Keller
Journal: Biol Psychiatry Date: 2017-07-13 Impact factor: 13.382

4. A polygenic burden of rare disruptive mutations in schizophrenia.

Authors: Shaun M Purcell; Jennifer L Moran; Menachem Fromer; Douglas Ruderfer; Nadia Solovieff; Panos Roussos; Colm O'Dushlaine; Kimberly Chambert; Sarah E Bergen; Anna Kähler; Laramie Duncan; Eli Stahl; Giulio Genovese; Esperanza Fernández; Mark O Collins; Noboru H Komiyama; Jyoti S Choudhary; Patrik K E Magnusson; Eric Banks; Khalid Shakir; Kiran Garimella; Tim Fennell; Mark DePristo; Seth G N Grant; Stephen J Haggarty; Stacey Gabriel; Edward M Scolnick; Eric S Lander; Christina M Hultman; Patrick F Sullivan; Steven A McCarroll; Pamela Sklar
Journal: Nature Date: 2014-01-22 Impact factor: 49.962

5. MAGMA: generalized gene-set analysis of GWAS data.

Authors: Christiaan A de Leeuw; Joris M Mooij; Tom Heskes; Danielle Posthuma
Journal: PLoS Comput Biol Date: 2015-04-17 Impact factor: 4.475

6. Identification of common genetic risk variants for autism spectrum disorder.

Authors: Jakob Grove; Stephan Ripke; Thomas D Als; Manuel Mattheisen; Raymond K Walters; Hyejung Won; Jonatan Pallesen; Esben Agerbo; Ole A Andreassen; Richard Anney; Swapnil Awashti; Rich Belliveau; Francesco Bettella; Joseph D Buxbaum; Jonas Bybjerg-Grauholm; Marie Bækvad-Hansen; Felecia Cerrato; Kimberly Chambert; Jane H Christensen; Claire Churchhouse; Karin Dellenvall; Ditte Demontis; Silvia De Rubeis; Bernie Devlin; Srdjan Djurovic; Ashley L Dumont; Jacqueline I Goldstein; Christine S Hansen; Mads Engel Hauberg; Mads V Hollegaard; Sigrun Hope; Daniel P Howrigan; Hailiang Huang; Christina M Hultman; Lambertus Klei; Julian Maller; Joanna Martin; Alicia R Martin; Jennifer L Moran; Mette Nyegaard; Terje Nærland; Duncan S Palmer; Aarno Palotie; Carsten Bøcker Pedersen; Marianne Giørtz Pedersen; Timothy dPoterba; Jesper Buchhave Poulsen; Beate St Pourcain; Per Qvist; Karola Rehnström; Abraham Reichenberg; Jennifer Reichert; Elise B Robinson; Kathryn Roeder; Panos Roussos; Evald Saemundsen; Sven Sandin; F Kyle Satterstrom; George Davey Smith; Hreinn Stefansson; Stacy Steinberg; Christine R Stevens; Patrick F Sullivan; Patrick Turley; G Bragi Walters; Xinyi Xu; Kari Stefansson; Daniel H Geschwind; Merete Nordentoft; David M Hougaard; Thomas Werge; Ole Mors; Preben Bo Mortensen; Benjamin M Neale; Mark J Daly; Anders D Børglum
Journal: Nat Genet Date: 2019-02-25 Impact factor: 38.330

7. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.

Authors: Shaun M Purcell; Naomi R Wray; Jennifer L Stone; Peter M Visscher; Michael C O'Donovan; Patrick F Sullivan; Pamela Sklar
Journal: Nature Date: 2009-07-01 Impact factor: 49.962

8. Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.

Authors: Sandra Sanchez-Roige; Abraham A Palmer; Pierre Fontanillas; Sarah L Elson; Mark J Adams; David M Howard; Howard J Edenberg; Gail Davies; Richard C Crist; Ian J Deary; Andrew M McIntosh; Toni-Kim Clarke
Journal: Am J Psychiatry Date: 2018-10-19 Impact factor: 18.112

9. Biological insights from 108 schizophrenia-associated genetic loci.

Authors:
Journal: Nature Date: 2014-07-22 Impact factor: 49.962

10. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors: Raymond K Walters; Renato Polimanti; Emma C Johnson; Jeanette N McClintick; Mark J Adams; Amy E Adkins; Fazil Aliev; Silviu-Alin Bacanu; Anthony Batzler; Sarah Bertelsen; Joanna M Biernacka; Tim B Bigdeli; Li-Shiun Chen; Toni-Kim Clarke; Yi-Ling Chou; Franziska Degenhardt; Anna R Docherty; Alexis C Edwards; Pierre Fontanillas; Jerome C Foo; Louis Fox; Josef Frank; Ina Giegling; Scott Gordon; Laura M Hack; Annette M Hartmann; Sarah M Hartz; Stefanie Heilmann-Heimbach; Stefan Herms; Colin Hodgkinson; Per Hoffmann; Jouke Jan Hottenga; Martin A Kennedy; Mervi Alanne-Kinnunen; Bettina Konte; Jari Lahti; Marius Lahti-Pulkkinen; Dongbing Lai; Lannie Ligthart; Anu Loukola; Brion S Maher; Hamdi Mbarek; Andrew M McIntosh; Matthew B McQueen; Jacquelyn L Meyers; Yuri Milaneschi; Teemu Palviainen; John F Pearson; Roseann E Peterson; Samuli Ripatti; Euijung Ryu; Nancy L Saccone; Jessica E Salvatore; Sandra Sanchez-Roige; Melanie Schwandt; Richard Sherva; Fabian Streit; Jana Strohmaier; Nathaniel Thomas; Jen-Chyong Wang; Bradley T Webb; Robbee Wedow; Leah Wetherill; Amanda G Wills; Jason D Boardman; Danfeng Chen; Doo-Sup Choi; William E Copeland; Robert C Culverhouse; Norbert Dahmen; Louisa Degenhardt; Benjamin W Domingue; Sarah L Elson; Mark A Frye; Wolfgang Gäbel; Caroline Hayward; Marcus Ising; Margaret Keyes; Falk Kiefer; John Kramer; Samuel Kuperman; Susanne Lucae; Michael T Lynskey; Wolfgang Maier; Karl Mann; Satu Männistö; Bertram Müller-Myhsok; Alison D Murray; John I Nurnberger; Aarno Palotie; Ulrich Preuss; Katri Räikkönen; Maureen D Reynolds; Monika Ridinger; Norbert Scherbaum; Marc A Schuckit; Michael Soyka; Jens Treutlein; Stephanie Witt; Norbert Wodarz; Peter Zill; Daniel E Adkins; Joseph M Boden; Dorret I Boomsma; Laura J Bierut; Sandra A Brown; Kathleen K Bucholz; Sven Cichon; E Jane Costello; Harriet de Wit; Nancy Diazgranados; Danielle M Dick; Johan G Eriksson; Lindsay A Farrer; Tatiana M Foroud; Nathan A Gillespie; Alison M Goate; David Goldman; Richard A Grucza; Dana B Hancock; Kathleen Mullan Harris; Andrew C Heath; Victor Hesselbrock; John K Hewitt; Christian J Hopfer; John Horwood; William Iacono; Eric O Johnson; Jaakko A Kaprio; Victor M Karpyak; Kenneth S Kendler; Henry R Kranzler; Kenneth Krauter; Paul Lichtenstein; Penelope A Lind; Matt McGue; James MacKillop; Pamela A F Madden; Hermine H Maes; Patrik Magnusson; Nicholas G Martin; Sarah E Medland; Grant W Montgomery; Elliot C Nelson; Markus M Nöthen; Abraham A Palmer; Nancy L Pedersen; Brenda W J H Penninx; Bernice Porjesz; John P Rice; Marcella Rietschel; Brien P Riley; Richard Rose; Dan Rujescu; Pei-Hong Shen; Judy Silberg; Michael C Stallings; Ralph E Tarter; Michael M Vanyukov; Scott Vrieze; Tamara L Wall; John B Whitfield; Hongyu Zhao; Benjamin M Neale; Joel Gelernter; Howard J Edenberg; Arpana Agrawal
Journal: Nat Neurosci Date: 2018-11-26 Impact factor: 24.884

36 in total

1. Molecular genetic overlap between posttraumatic stress disorder and sleep phenotypes.

Authors: Mackenzie J Lind; Leslie A Brick; Philip R Gehrman; Laramie E Duncan; Bizu Gelaye; Adam X Maihofer; Caroline M Nievergelt; Nicole R Nugent; Murray B Stein; Ananda B Amstadter
Journal: Sleep Date: 2020-04-15 Impact factor: 5.849

Review 2. The Role of the Circadian System in Attention Deficit Hyperactivity Disorder.

Authors: Upasana Bondopadhyay; Unai Diaz-Orueta; Andrew N Coogan
Journal: Adv Exp Med Biol Date: 2021 Impact factor: 2.622

3. Cognitive neuroscience at the crossroads.

Authors:
Journal: Nature Date: 2022-08 Impact factor: 69.504

4. Principal Component Analysis Reduces Collider Bias in Polygenic Score Effect Size Estimation.

Authors: Nathaniel S Thomas; Peter Barr; Fazil Aliev; Mallory Stephenson; Sally I-Chun Kuo; Grace Chan; Danielle M Dick; Howard J Edenberg; Victor Hesselbrock; Chella Kamarajan; Samuel Kuperman; Jessica E Salvatore
Journal: Behav Genet Date: 2022-06-08 Impact factor: 2.965

5. GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task.

Authors: Lance O Bauer; Jonathan M Covault
Journal: Clin Neurophysiol Date: 2020-04-02 Impact factor: 3.708

6. On the path towards personalized medicine: Implications of pharmacogenetic studies of alcohol use disorder medications.

Authors: Steven J Nieto; Erica N Grodin; Lara A Ray
Journal: Expert Rev Precis Med Drug Dev Date: 2020-02-10

Review 7. Dissecting polygenic signals from genome-wide association studies on human behaviour.

Authors: Abdel Abdellaoui; Karin J H Verweij
Journal: Nat Hum Behav Date: 2021-05-13

Review 8. Twin studies to GWAS: there and back again.

Authors: Naomi P Friedman; Marie T Banich; Matthew C Keller
Journal: Trends Cogn Sci Date: 2021-07-24 Impact factor: 24.482

9. Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa.

Authors: Danielle M Adams; William R Reay; Michael P Geaghan; Murray J Cairns
Journal: Neuropsychopharmacology Date: 2020-09-13 Impact factor: 7.853

10. Polygenic risk scoring to assess genetic overlap and protective factors influencing posttraumatic stress, depression, and chronic pain after motor vehicle collision trauma.

Authors: Jarred J Lobo; Samuel A McLean; Andrew S Tungate; David A Peak; Robert A Swor; Niels K Rathlev; Phyllis L Hendry; Sarah D Linnstaedt
Journal: Transl Psychiatry Date: 2021-06-29 Impact factor: 6.222