| Literature DB >> 3096718 |
Abstract
The dopa decarboxylase gene (Ddc) has been isolated from Drosophila virilis and introduced into the germ-line of Drosophila melanogaster by P-element mediated transformation. The integrated gene is induced at the correct stages during development with apparently normal tissue specificity, indicating that cis-acting elements required for regulation are functionally conserved between the two species. A comparison of the DNA sequences from the 5' flanking regions reveals a cluster of small (8-16 bp) conserved sequence elements within 150 bp upstream of the RNA startpoint, a region required for normal expression of the D. melanogaster Ddc gene.Entities:
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Year: 1986 PMID: 3096718 PMCID: PMC1167114 DOI: 10.1002/j.1460-2075.1986.tb04498.x
Source DB: PubMed Journal: EMBO J ISSN: 0261-4189 Impact factor: 11.598