Sampada Bhave1, Matthew F Koff2, S Sivaram Kaushik3, Hollis G Potter2, Kevin M Koch1. 1. Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin. 2. MRI Laboratory, Hospital for Special Surgery, New York, New York. 3. MR Applications and Workflow, GE Healthcare, Waukesha, Wisconsin.
Abstract
PURPOSE: Due to host-mediated adverse reaction to metallic debris, there is an increasing need for noninvasive assessment of the soft tissue surrounding large joint arthroplasties. Quantitative T 2 mapping can be beneficial for tissue characterization and early diagnosis of tissue pathology but current T 2 mapping techniques lack the capability to image near metal hardware. A novel multi-spectral T 2 mapping technique is proposed to address this unmet need. METHODS: A T 2 mapping pulse sequence based on routinely implemented 3D multi-spectral imaging (3D-MSI) pulse sequences is described and demonstrated. The 3D-MSI pulse sequence is altered to acquire images at 2 echo times. Phantom and knee experiments were performed to assess the quantitative capabilities of the sequence in comparison to a commercially available T 2 mapping sequence. The technique was demonstrated for use within a clinical protocol in 2 total hip arthroplasty (THA) cases to assess T 2 variations within the periprosthetic joint space. RESULTS: The proposed multi-spectral T 2 mapping technique agreed, within experimental errors, with T 2 values derived from a commercially available clinical standard of care T 2 mapping sequence. The same level of agreement was observed in quantitative phantoms and in vivo experiments. In THA cases, the method was able to assess variations of T 2 within the synovial envelope immediately adjacent to implant interfaces. CONCLUSIONS: The proposed 3D-MSI T 2 mapping sequence was successfully demonstrated in assessing tissue T 2 variations near metal implants.
PURPOSE: Due to host-mediated adverse reaction to metallic debris, there is an increasing need for noninvasive assessment of the soft tissue surrounding large joint arthroplasties. Quantitative T 2 mapping can be beneficial for tissue characterization and early diagnosis of tissue pathology but current T 2 mapping techniques lack the capability to image near metal hardware. A novel multi-spectral T 2 mapping technique is proposed to address this unmet need. METHODS: A T 2 mapping pulse sequence based on routinely implemented 3D multi-spectral imaging (3D-MSI) pulse sequences is described and demonstrated. The 3D-MSI pulse sequence is altered to acquire images at 2 echo times. Phantom and knee experiments were performed to assess the quantitative capabilities of the sequence in comparison to a commercially available T 2 mapping sequence. The technique was demonstrated for use within a clinical protocol in 2 total hip arthroplasty (THA) cases to assess T 2 variations within the periprosthetic joint space. RESULTS: The proposed multi-spectral T 2 mapping technique agreed, within experimental errors, with T 2 values derived from a commercially available clinical standard of care T 2 mapping sequence. The same level of agreement was observed in quantitative phantoms and in vivo experiments. In THA cases, the method was able to assess variations of T 2 within the synovial envelope immediately adjacent to implant interfaces. CONCLUSIONS: The proposed 3D-MSI T 2 mapping sequence was successfully demonstrated in assessing tissue T 2 variations near metal implants.
Authors: K M Koch; A C Brau; W Chen; G E Gold; B A Hargreaves; M Koff; G C McKinnon; H G Potter; K F King Journal: Magn Reson Med Date: 2011-01 Impact factor: 4.668
Authors: Catherine L Hayter; Matthew F Koff; Parina Shah; Kevin M Koch; Theodore T Miller; Hollis G Potter Journal: AJR Am J Roentgenol Date: 2011-09 Impact factor: 3.959
Authors: Hollis G Potter; Bryan J Nestor; Carolyn M Sofka; Stephanie T Ho; Lance E Peters; Eduardo A Salvati Journal: J Bone Joint Surg Am Date: 2004-09 Impact factor: 5.284
Authors: Reed F Busse; Anja C S Brau; Anthony Vu; Charles R Michelich; Ersin Bayram; Richard Kijowski; Scott B Reeder; Howard A Rowley Journal: Magn Reson Med Date: 2008-09 Impact factor: 4.668
Authors: Jacky Cheung; John P Neri; Madeleine A Gao; Bin Lin; Alissa J Burge; Hollis G Potter; Kevin M Koch; Matthew F Koff Journal: HSS J Date: 2021-02-25