Literature DB >> 30731446

Physics of active emulsions.

Christoph A Weber1, David Zwicker, Frank Jülicher, Chiu Fan Lee.   

Abstract

Phase separating systems that are maintained away from thermodynamic equilibrium via molecular processes represent a class of active systems, which we call active emulsions. These systems are driven by external energy input, for example provided by an external fuel reservoir. The external energy input gives rise to novel phenomena that are not present in passive systems. For instance, concentration gradients can spatially organise emulsions and cause novel droplet size distributions. Another example are active droplets that are subject to chemical reactions such that their nucleation and size can be controlled, and they can divide spontaneously. In this review, we discuss the physics of phase separation and emulsions and show how the concepts that govern such phenomena can be extended to capture the physics of active emulsions. This physics is relevant to the spatial organisation of the biochemistry in living cells, for the development of novel applications in chemical engineering and models for the origin of life.

Year:  2019        PMID: 30731446     DOI: 10.1088/1361-6633/ab052b

Source DB:  PubMed          Journal:  Rep Prog Phys        ISSN: 0034-4885


  33 in total

1.  Formation of liquid-like cellular organelles depends on their composition.

Authors:  Chiu Fan Lee
Journal:  Nature       Date:  2020-05       Impact factor: 49.962

2.  'RNA modulation of transport properties and stability in phase-separated condensates.

Authors:  Andrés R Tejedor; Adiran Garaizar; Jorge Ramírez; Jorge R Espinosa
Journal:  Biophys J       Date:  2021-11-09       Impact factor: 4.033

3.  Quantitative theory for the diffusive dynamics of liquid condensates.

Authors:  Lars Hubatsch; Louise M Jawerth; Celina Love; Jonathan Bauermann; Ty Dora Tang; Stefano Bo; Anthony A Hyman; Christoph A Weber
Journal:  Elife       Date:  2021-10-12       Impact factor: 8.140

4.  Active emulsions in living cell membranes driven by contractile stresses and transbilayer coupling.

Authors:  Suvrajit Saha; Amit Das; Chandrima Patra; Anupama Ambika Anilkumar; Parijat Sil; Satyajit Mayor; Madan Rao
Journal:  Proc Natl Acad Sci U S A       Date:  2022-07-22       Impact factor: 12.779

5.  Evolved interactions stabilize many coexisting phases in multicomponent liquids.

Authors:  David Zwicker; Liedewij Laan
Journal:  Proc Natl Acad Sci U S A       Date:  2022-07-06       Impact factor: 12.779

6.  Dynamic metastable long-living droplets formed by sticker-spacer proteins.

Authors:  Srivastav Ranganathan; Eugene I Shakhnovich
Journal:  Elife       Date:  2020-06-02       Impact factor: 8.140

7.  Physical theory of biological noise buffering by multicomponent phase separation.

Authors:  Dan Deviri; Samuel A Safran
Journal:  Proc Natl Acad Sci U S A       Date:  2021-06-22       Impact factor: 11.205

8.  Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates.

Authors:  Anatol W Fritsch; Andrés F Diaz-Delgadillo; Omar Adame-Arana; Carsten Hoege; Matthäus Mittasch; Moritz Kreysing; Mark Leaver; Anthony A Hyman; Frank Jülicher; Christoph A Weber
Journal:  Proc Natl Acad Sci U S A       Date:  2021-09-14       Impact factor: 11.205

9.  Phase separation in fluids with many interacting components.

Authors:  Krishna Shrinivas; Michael P Brenner
Journal:  Proc Natl Acad Sci U S A       Date:  2021-11-09       Impact factor: 11.205

10.  Controlling biomolecular condensates via chemical reactions.

Authors:  Jan Kirschbaum; David Zwicker
Journal:  J R Soc Interface       Date:  2021-06-30       Impact factor: 4.118

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