Literature DB >> 30725125

[Diagnostics and treatment of olfactory dysfunction].

M Damm1,2, L Schmitl3, C A Müller4, A Welge-Lüssen5, T Hummel6.   

Abstract

BACKGROUND: Dysosmia is one of the most common disorders in otorhinolaryngology. However, epidemiological data are lacking and treatment strategies are insufficiently standardized.
OBJECTIVE: The aim of this study was to evaluate the frequency of causes of olfactory disorders and the different therapeutic approaches used in ENT departments in German-speaking countries. The results were also compared to findings of the survey in 2000. Furthermore, a systematic review of treatment strategies was conducted.
MATERIALS AND METHODS: In 2010, a two-page survey addressing olfactory dysfunction was sent to all ENT departments in German-speaking countries. The literature review included sources such as PubMed, the Cochrane Library, and relevant guidelines.
RESULTS: The diagnosis of dysosmia was made less frequently in ENT departments (decrease of 52%). The three most widely used therapeutic approaches were corticosteroids (topical and systemic) and systemic antibiotics. There is evidence in the literature showing a small to medium effect of topical steroids in sinonasal smell disorders.
CONCLUSION: Since a 50% decrease in the prevalence of olfactory disturbances is unlikely, the lower patient numbers may relate to a more critical diagnosis. The use of olfactory training in clinics has increased significantly (from <6% to up to 23%). The use of topical steroids for sinonasal dysosmia is evidence based. Smell training is a safe and effective treatment strategy, especially in post-infectious and post-traumatic olfactory disorders.

Entities:  

Keywords:  Anosmia; Epidemiology; Hyposmia; Sinunasal; Steroids

Mesh:

Substances:

Year:  2019        PMID: 30725125     DOI: 10.1007/s00106-019-0614-x

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  14 in total

Review 1.  Olfactory outcomes in chronic rhinosinusitis with nasal polyposis after medical treatments: a systematic review and meta-analysis.

Authors:  Sarfaraz M Banglawala; Samuel L Oyer; Shivangi Lohia; Alkis J Psaltis; Zachary M Soler; Rodney J Schlosser
Journal:  Int Forum Allergy Rhinol       Date:  2014-11-14       Impact factor: 3.858

2.  Normative data for the "Sniffin' Sticks" including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects.

Authors:  T Hummel; G Kobal; H Gudziol; A Mackay-Sim
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-09-23       Impact factor: 2.503

3.  [Diagnosis of olfactory disorders].

Authors:  V A Schriever; N Abolmaali; A Welge-Lüssen
Journal:  HNO       Date:  2014-12       Impact factor: 1.284

4.  Medical treatment of traumatic anosmia.

Authors:  Rong-San Jiang; Chih-Wen Twu; Kai-Li Liang
Journal:  Otolaryngol Head Neck Surg       Date:  2015-02-24       Impact factor: 3.497

5.  A study on the frequency of olfactory dysfunction.

Authors:  B N Landis; C G Konnerth; T Hummel
Journal:  Laryngoscope       Date:  2004-10       Impact factor: 3.325

6.  [Olfactory dysfunction : Update on diagnosis and treatment].

Authors:  M Kühn; N Abolmaali; M Smitka; D Podlesek; T Hummel
Journal:  HNO       Date:  2016-07       Impact factor: 1.284

7.  Olfactory function following nasal surgery.

Authors:  Jürgen Pade; Thomas Hummel
Journal:  Laryngoscope       Date:  2008-07       Impact factor: 3.325

8.  Olfactory training is helpful in postinfectious olfactory loss: a randomized, controlled, multicenter study.

Authors:  Michael Damm; Louisa K Pikart; Heike Reimann; Silke Burkert; Önder Göktas; Boris Haxel; Sabine Frey; Ioannis Charalampakis; Achim Beule; Berthold Renner; Thomas Hummel; Karl-Bernd Hüttenbrink
Journal:  Laryngoscope       Date:  2013-09-19       Impact factor: 3.325

Review 9.  [Olfactory dysfunctions. Epidemiology and therapy in Germany, Austria and Switzerland].

Authors:  M Damm; A Temmel; A Welge-Lüssen; H E Eckel; M-P Kreft; J P Klussmann; H Gudziol; K-B Hüttenbrink; T Hummel
Journal:  HNO       Date:  2004-02       Impact factor: 1.284

10.  A double-blind, randomized, placebo-controlled trial of macrolide in the treatment of chronic rhinosinusitis.

Authors:  Ben Wallwork; William Coman; Alan Mackay-Sim; Lennart Greiff; Anders Cervin
Journal:  Laryngoscope       Date:  2006-02       Impact factor: 3.325

View more
  8 in total

Review 1.  Olfactory and gustatory disorders in COVID-19.

Authors:  Ludger Klimek; Jan Hagemann; Julia Döge; Laura Freudelsperger; Mandy Cuevas; Felix Klimek; Thomas Hummel
Journal:  Allergo J Int       Date:  2022-06-20

Review 2.  [Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium-an overview].

Authors:  P Dörig; N Gunder; M Witt; A Welge-Lüssen; T Hummel
Journal:  HNO       Date:  2021-05-14       Impact factor: 1.284

3.  [Temporary hyposmia in COVID-19 patients].

Authors:  S Bocksberger; W Wagner; T Hummel; W Guggemos; M Seilmaier; M Hoelscher; C-M Wendtner
Journal:  HNO       Date:  2020-06       Impact factor: 1.284

4.  Smell disorders in COVID-19 patients: role of olfactory training: A protocol for systematic review and meta-analysis.

Authors:  Yu Zhang; Tao Mei; Ying Chen; Lina Wang; Lulian Jiang; Ke Liu; Liping Zhao; Ziyu Luo; Wenxin Chi; Xiangyu Zhu
Journal:  Medicine (Baltimore)       Date:  2021-02-26       Impact factor: 1.817

5.  Neurological manifestations of post-COVID-19 syndrome S1-guideline of the German society of neurology.

Authors:  Christiana Franke; Peter Berlit; Harald Prüss
Journal:  Neurol Res Pract       Date:  2022-07-18

6.  Case Report: Acupuncture is an effective treatment for olfactory dysfunction in the post COVID-19 condition.

Authors:  Akira Morita; Aya Murakami; Takushu Uchihara; Noriyuki Ohashi; Koichi Ryu; Yuki Watanabe; Sadayuki Ochi; Kazuho Okudaira; Yoshiro Hirasaki; Takao Namiki
Journal:  Front Neurol       Date:  2022-08-23       Impact factor: 4.086

7.  First-episode olfactory hallucination in a patient with anxiety disorder: A case report.

Authors:  Xingmei Jiang; Yiwen Yuan; Zhixiong Li; Ying Ou; Zhe Li
Journal:  Front Psychiatry       Date:  2022-09-20       Impact factor: 5.435

8.  Acupuncture is associated with a positive effect on odour discrimination in patients with postinfectious smell loss-a controlled prospective study.

Authors:  Tanja Drews; Thomas Hummel; Bettina Rochlitzer; Bettina Hauswald; Antje Hähner
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-05-25       Impact factor: 2.503

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.