Na J Seo1, Michelle L Woodbury2, Leonardo Bonilha3, Viswanathan Ramakrishnan4, Steven A Kautz2, Ryan J Downey5, Blair H S Dellenbach2, Abigail W Lauer4, Caroline M Roark6, Lauren E Landers6, Sarah K Phillips6, Amanda A Vatinno7. 1. Division of Occupation Therapy, Department of Health Professions, Department of Health Sciences and Research, Medical University of South Carolina, 151B Rutledge Ave, Charleston, SC 29425 (USA). 2. Department of Health Sciences and Research, Medical University of South Carolina. 3. Department of Neurology, Medical University of South Carolina. 4. Department of Public Health Sciences, Medical University of South Carolina. 5. Department of Health Professions, Medical University of South Carolina. 6. Division of Occupational Therapy, Medical University of South Carolina. 7. College of Health Professions, Medical University of South Carolina.
Abstract
BACKGROUND:Peripheral sensory stimulation has been used in conjunction with upper extremity movement therapy to increase therapy-induced motor gains in patients with stroke. The limitation is that existing sensory stimulation methods typically interfere with natural hand tasks and thus are administered prior to therapy, requiring patients' time commitment. To address this limitation, we developed TheraBracelet. This novel stimulation method provides subthreshold (ie, imperceptible) vibratory stimulation to the wrist and can be used during hand tasks/therapy without interfering with natural hand tasks. OBJECTIVE: The objective was to determine the feasibility of using TheraBracelet during therapy to augment motor recovery after stroke. DESIGN: The design was a triple-blinded pilot randomized controlled trial. METHODS:Twelve chronic stroke survivors were assigned to the treatment or control group. All participants completed 2-hour task practice therapy sessions thrice weekly for 2 weeks. Both groups wore a small vibrator on the paretic wrist, which was turned on to provide TheraBracelet stimulation for the treatment group and turned off for the control group to provide sham stimulation. Outcome measures (Box and Block Test [BBT] and Wolf Motor Function Test [WMFT]) were obtained at baseline, 6 days after therapy, and at follow-up 19 days after therapy. RESULTS: The intervention was feasible with no adverse events. The treatment group significantly improved their BBT scores after therapy and at follow-up compared with baseline, whereas the control group did not. For WMFT, the group × time interaction was short of achieving significance. Large effect sizes were obtained (BBT d = 1.43, WMFT d = 0.87). No indication of desensitization to TheraBracelet stimulation was observed. LIMITATIONS: The limitation was a small sample size. CONCLUSIONS: TheraBracelet could be a promising therapy adjuvant for upper extremity recovery after stroke.
RCT Entities:
BACKGROUND: Peripheral sensory stimulation has been used in conjunction with upper extremity movement therapy to increase therapy-induced motor gains in patients with stroke. The limitation is that existing sensory stimulation methods typically interfere with natural hand tasks and thus are administered prior to therapy, requiring patients' time commitment. To address this limitation, we developed TheraBracelet. This novel stimulation method provides subthreshold (ie, imperceptible) vibratory stimulation to the wrist and can be used during hand tasks/therapy without interfering with natural hand tasks. OBJECTIVE: The objective was to determine the feasibility of using TheraBracelet during therapy to augment motor recovery after stroke. DESIGN: The design was a triple-blinded pilot randomized controlled trial. METHODS: Twelve chronic stroke survivors were assigned to the treatment or control group. All participants completed 2-hour task practice therapy sessions thrice weekly for 2 weeks. Both groups wore a small vibrator on the paretic wrist, which was turned on to provide TheraBracelet stimulation for the treatment group and turned off for the control group to provide sham stimulation. Outcome measures (Box and Block Test [BBT] and Wolf Motor Function Test [WMFT]) were obtained at baseline, 6 days after therapy, and at follow-up 19 days after therapy. RESULTS: The intervention was feasible with no adverse events. The treatment group significantly improved their BBT scores after therapy and at follow-up compared with baseline, whereas the control group did not. For WMFT, the group × time interaction was short of achieving significance. Large effect sizes were obtained (BBT d = 1.43, WMFT d = 0.87). No indication of desensitization to TheraBracelet stimulation was observed. LIMITATIONS: The limitation was a small sample size. CONCLUSIONS:TheraBracelet could be a promising therapy adjuvant for upper extremity recovery after stroke.
Authors: S M Golaszewski; C M Siedentopf; F Koppelstaetter; P Rhomberg; G M Guendisch; A Schlager; E Gallasch; W Eisner; S R Felber; F M Mottaghy Journal: Neurology Date: 2004-06-22 Impact factor: 9.910
Authors: James R Carey; Teresa J Kimberley; Scott M Lewis; Edward J Auerbach; Lisa Dorsey; Peter Rundquist; Kamil Ugurbil Journal: Brain Date: 2002-04 Impact factor: 13.501
Authors: Na Jin Seo; Leah R Enders; Andrew Fortune; Shannon Cain; Amanda A Vatinno; Eli Schuster; Viswanathan Ramakrishnan; Wuwei Feng Journal: Transl Stroke Res Date: 2019-08-23 Impact factor: 6.829
Authors: Amanda A Vatinno; Christian Schranz; Annie N Simpson; Viswanathan Ramakrishnan; Leonardo Bonilha; N J Seo Journal: NeuroRehabilitation Date: 2022 Impact factor: 2.138
Authors: Na Jin Seo; Viswanathan Ramakrishnan; Michelle L Woodbury; Leonardo Bonilha; Christian Finetto; Christian Schranz; Gabrielle Scronce; Kristen Coupland; Jenna Blaschke; Adam Baker; Keith Howard; Caitlyn Meinzer; Craig A Velozo; Robert J Adams Journal: Trials Date: 2022-04-05 Impact factor: 2.279
Authors: Mary E Stoykov; Courtney Heidle; Shamshir Kang; Lisa Lodesky; Lindsay E Maccary; Sangeetha Madhavan Journal: OTJR (Thorofare N J) Date: 2021-07-26