Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis.

Studies on the prevalence of hypertension in Vietnam have reported various estimates. There is no up-to-date assessment of the evidence on the magnitude of hypertension in Vietnam. Search engines for scientific and gray literature were used to identify relevant records for eligibility screening and quality assessment. Data from selected articles were extracted using standardized spreadsheets. Statistical analysis included estimating pooled prevalence and odds ratio, heterogeneity evaluation, meta-regression, and subgroup analysis, in addition to sensitivity analysis and publication bias evaluation. The pooled prevalence of measured hypertension in Vietnam was 21.1% (95% confidence interval = 18.5-23.7) based on 10 studies, and 18.4% (95% confidence interval = 15.2-21.8) based on 3 national surveys. Lower pooled prevalence was estimated for hypertension awareness (9.3%) and hypertension treatment (4.7%). The pooled prevalence of measured hypertension is significantly higher among men. The pooled prevalence of measured hypertension and hypertension awareness and treatment were significantly lower in rural settings. There is a need to strengthen efforts for primary and secondary prevention and disease management to reduce morbidity and mortality, especially in rural residence settings.

Introduction

Rationale

Noncommunicable diseases caused 72.3% of global deaths in 2016, with cardiovascular diseases (CVDs) representing the highest proportion of these deaths.[1] Primary hypertension (HTN) is one of the CVDs that is caused by different physiological and behavioral risk factors such as harmful use of alcohol, high body mass index, lead exposure, tobacco use, and a high-salt diet. Concurrently, high blood pressure (HBP) as a physiological risk factor contributes to a high burden of other noncommunicable diseases, for example, strokes and chronic kidney diseases.[2,3] While the burden of HTN is increasing globally,[1,4] low- and middle-income countries (LMICs) are enduring a higher burden due to their demographic, socioeconomic, urban, and/or epidemiological transitions.[5]

Primary prevention for HTN/HBP is possible by managing its risk factors; besides, HBP/HTN can be considered a modifiable risk factor since its management and control are secondary prevention measures for associated complications.[6] Management of HBP/HTN includes promoting and supporting behavioral changes toward a more healthy living, in addition to treating and controlling through pharmacological interventions.[7] In LMICs, management and control efforts are more complicated due to their weak health systems and limited resources.[6,8] Vietnam established its national HTN program in 2008.[9] Since then, studies on the prevalence of HTN, including few national samples, have been published and varied in their estimates. In 2012, a time trends analysis for blood pressure was performed using a dataset compiled by multiple cross-sectional studies; the analysis showed a significant increase of HTN prevalence of 0.9% per year between 2001 and 2009.[10] There is no up-to-date assessment of the evidence on the magnitude of HTN in Vietnam. Consolidating available data in the literature into a national estimate of the prevalence of HTN is crucial to provide information for future policy regarding population need, management, and control of HTN in Vietnam.

Objectives

This article aims to perform a systematic review and a meta-analysis of the prevalence of HTN in Vietnam and its associated risk factors reported as relevant to the Vietnamese population, in addition to the prevalence of HTN awareness and treatment.

Methods

The reporting of this review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.[11]

Eligibility Criteria

Eligibility criteria for inclusion were community-based (ie, population-based) studies to detect hypertensive subjects among adult population (≥18 years) living in Vietnam. Study design could be cross-sectional or cohort. Exclusion criteria were the following: the population was refugees and migrants living outside Vietnam in addition to war veterans who are not Vietnamese; records that were abstracts, conference posters, reviews, and meta-analysis; articles reporting duplicated data; and studies that were facility-based or did not use random sampling.

Information Sources and Search Strategy

The following databases were searched: PubMed, EMBASE, CINAHL, and Web of Science (performed on October 13, 2017), in addition to gray literature (eg, governmental and international documents) through Google and relevant websites. The search terms incorporated a combination of keywords and index terms related to HTN (eg, CVDs, HTN, HBP) and the outcome (eg, prevalence, burden, morbidity, health need). Detailed tables on the search terms used are provided in Appendix 1 (all appendixes are available online). Furthermore, the reference lists of retrieved full-text records were searched to identify additional relevant records. The search strategy focused on records published in English; however, we reviewed relevant Vietnamese websites and documents to look for information on national surveys that might be only available in Vietnamese and not published in English.

Selection Process

One researcher (LM) screened the title and abstract using the Rayyan application.[12] Then, full-texts were retrieved for selected records and assessed again for their eligibility. Finally, quality assessment was performed during data extraction to make a final decision on record’s inclusion in the meta-analysis.

Data Extraction

The data extraction was done using standardized spreadsheets. Since one researcher (LM) was available to perform the data extraction, it was conducted twice within 1 month to compare the results between 2 separate time points.[13] The information extracted included (1) study characteristics: author, publication year, objective, project related to the study (if applicable), data collection year, location, sampling technique, sample size and response rate, HTN definition used, and type of statistical analysis and adjustment variables; (2) participants characteristics: age group targeted, mean age, proportions of women, and residence setting; and finally (3) outcome(s) of interest: number of hypertensive subjects in total and by risk factors categories, in addition to number of those aware of their HTN condition and/or treated.

Quality Assessment

Studies were assessed based on a checklist of 5 criteria covering both study and reporting qualities[14]; these criteria were also applicable for assessing the risk of bias at study level. The checklist included (1) appropriate sampling strategy, (2) response rate >80.0%, (3) clear procedures for blood pressure measurement including use of World Health Organization’s guidelines of STEPwise approach to surveillance of noncommunicable diseases[15] to develop study protocol or providing detailed information on type of blood pressure measurement device and number of readings taken to measure the outcome, (4) definition of HTN used is measured HTN at ≥140/90 mm Hg levels, and (5) at least one quality assurance method such as training of data collectors, pretesting, and supervision. High-quality studies (with a complete score of 5) were included for meta-analysis.

Operationalization of Summary Measures

Summary measures included the following: first, the prevalence of HTN; second, the prevalence of HTN awareness; third, the prevalence of HTN treatment; and fourth, factors associated with HTN and sex, expressed as a crude odds ratio (OR).

Statistical Analysis

The pooled prevalence was weighted by inverse variance method, with the use of Freeman-Tukey double arcsine transformation to stabilize the proportions calculated for each study. The pooled OR for the association between HTN and reported risk factors was calculated using Mantel-Haenszel method. Due to the expected heterogeneity among studies, DerSimonian-Laird random-effects model was used to compute the effect estimates; however, the forest plots included results of the fixed-effect model as well. Assessment of heterogeneity comprised calculating τ2 statistic and I2 statistic. Tau-squared statistic provides an estimate of the between-study variance, in which a value of >1.0 suggests the presence of substantial statistical heterogeneity. I-squared statistic provides an estimate of the percentage of the variability in effect estimate that is due to heterogeneity rather than sampling error or chance differences where values of 25.0%, 50.0%, and 75.0% are interpreted as low, medium, and high heterogeneity, respectively.

The potential modifying effects of 7 study-level variables on the pooled prevalence of HTN were assessed using univariate mixed-effects meta-regression analyses and subgroup analysis. The included variables were data collection year, study publication year, use of STEPS protocols, type of used measurement device, proportion of women, youngest age group targeted, sample’s mean age, and residence settings. For subgroup differences, Cochran’s Q test (χ2) was performed, where significant P < .10 suggests evidence of heterogeneity.

Sensitivity analyses were performed by removing studies with the smallest sample sizes and outlier results. Finally, publication bias to assess the risk of bias across studies was conducted by evaluating funnel plot asymmetry using Egger’s linear regression test and Begg’s rank correlation test, as significant P value suggests the presence of statistical publication bias.

The results reported the pooled estimates with their 95% confidence interval (CI). CI for pooled prevalence was calculated using an “exact” binomial interval (ie, Clopper-Pearson interval). Significance was set at P < .05. The analysis was conducted using “meta” and “metafor” packages of R software.[16,17]

Results

Study Selection

There were 1319 records identified from the database search and 34 from the manual search (Figure 1). Of these, 429 were duplicates, and 857 were excluded based on “title and abstract” screening. After full-text assessment of the remaining 67 articles, 25 studies were found to be eligible.[18-42]

Figure 1.

Flow chart of records retrieved, screened and included in the systematic review and meta-analysis

Of the 25 eligible studies, 15 studies (60.0%) did not meet all 5 quality criteria.[18,19,21,23,26,29,34-42] Excluded studies comprise 70.9% of overall participants because 2 national surveys had low response rate.[18,19] Ten studies, with a population of 44 941 subjects, were included in this meta-analysis.[20,20,22,24,25,27,28,30-33] Detailed tables on the quality assessment are available in Appendix 2.

Study Characteristics

An overview of the included articles is available in Table 1. All studies are population-based observational cross-sectional design. Seven studies focused on HTN as a primary outcome,[20,20,27,28,30-33] while the rest focused on other related diseases or risk factors and had HTN as a secondary outcome. There were 3 national studies that comprised 66.6% of total subjects[27,31,32]; the rest were conducted in 4 regions: North East (n = 2; 13.6% of total subjects), Red River Delta (n = 2; 8.9% of total subjects), North Central and Central Coastal Areas (n = 2; 5.8% of total subjects), and South East (n = 1; 5.0% of total subjects). Three studies had an equal proportion of females and males in their samples, while the rest had higher proportions for females. Three studies reported age categories only; the mean age reported from 10 studies was 48.1 ± 4.6. For further analysis regarding residence settings, the studies were classified using the following criteria: rural settings if they covered >75.0% rural residents (n = 5); urban settings if they covered ≤30.0% rural residents (n = 2); and mixed rural/urban settings (n = 3) where the proportion of rural residents ranged between 50.8% and 65.9%. Results of meta-analysis are shown in Table 2.

Table 1.

Study Characteristics.

#	First Author, Year (Project)	Data Collection Year	Study Focus	Province, Region	Population	Sampling Technique	Use of STEPS Protocols	Sample Size, n	Response Rate, %	Women, %	Mean Age, n	Rural Residents, %	Residence Setting
1	Minh, 2006 (FilaBavi HDSS)	2002	Hypertension	Hanoi, Red River Delta	25-64 years	Random selection from database	Yes	1996	99.8	50.0	NR	100.0	Rural
2	Hoang, 2007 (FilaBavi HDSS)	2005	Risk factors of chronic diseases	Hanoi, Red River Delta	25-64 years	Random selection from database	Yes	1984	99.2	50.3	NR	100.0	Rural
3	Ta, 2010	NR	Type 2 diabetes mellitus	HCMC, South East	30-70 years	Random sample, with PPS	NR	2330	90.0	69.1	50.0	0.0	Urban
4	Fitzpatrick, 2012	2010	Risk factors and symptoms of stroke	Da Nang, North Central, and Central Coastal Areas	≥35 years	Multistage clustered sampling	Yes	1621	94.5	56.1	52.0	30.4	Urban
5	Son, 2012 (NESH, STEPS survey)	2002-2008	Hypertension	National, 8 provinces	≥25 years	Multistage stratified sampling[a]	Yes	9823	93.0	60.8	42.7	50.8	Mixed
6	Ha, 2013	2011	Hypertension	Thai Nguyen, North East	≥25 years	Multistage stratified clustered, with PPS[a]	NR	2348	81.5	56.3	45.0	82.8	Rural
7	Nguyen, 2014	2012	Hypertension	Thai Nguyen, North East	35-64 years	Random sample in 4 communes	NR	3779	86.5	56.7	47.4	100.0	Rural
8	Do, 2015 (NAOS)	2005	Hypertension	National, 8 provinces	25-64 years	Multistage stratified clustered, with PPS[a,b,c]	Yes	17 199	97.0	50.7	44.2	76.4	Rural
9	Ministry of Health, 2016	2015	Hypertension	National, 63 provinces	18-69 years	Multistage stratified clustered, with PPS[b,c]	Yes	2590	79.8	57.0	NR	55.2	Mixed
10	Hien, 2018	2015	Hypertension	Thua Thien Hue, North Central, and Central Coastal Areas	40-64 years	Multistage clustered sampling	Yes	969	80.8	56.1	55.5	65.9	Mixed

Abbreviations: STEPS, STEPwise approach to surveillance of noncommunicable diseases; FilaBavi HDSS, Health and Demographic Surveillance System at Ba Vi District, part of INDEPTH Network; NR, not reported; PPS, probability proportional to size; NESH, National Epidemiological Survey on Hypertension and Its Risk Factors; NAOS, National Adult Overweight Survey.

Stratified by geographical regions.

Stratified by age and sex strata.

Stratified by urban/rural settings.

Residence settings that are either totally rural or urban are indicated in bold.

Table 2.

Results of Meta-Analysis (Forest Plots Are Available in Appendices).

	Prevalence of Measured Hypertension							Prevalence of Hypertension Awareness							Prevalence of Hypertension Treatment
	k	Pooled	95% CI		τ2	I 2	P *	k	Pooled	95% CI		τ2	I 2	P *	k	Pooled	95% CI		τ2	I 2	P *
Studies included in meta-analysis	10	21.1	18.5	23.7	0.0026	97.6		6	9.3	5.3	14.3	0.0094	99.4		7	4.7	2.6	7.3	0.0056	99.0
Studies with national samples	3	18.4	15.2	21.8	0.0014	97.9		2	8.4	3.0	16.3	0.0075	99.7		3	4.8	1.9	9.0	0.0052	99.4
Subgroup analyses
Sex
Men	9	26.4	23.1	29.9	0.0033	95.9	<.01	5	10.3	5.8	15.9	0.0088	98.7	.73	5	5.1	2.7	8.2	0.0050	97.8	.95
Women	9	16.6	13.4	20.0	0.0044	97.6		5	8.9	3.9	15.7	0.0138	99.3		5	5.0	2.0	9.1	0.0085	98.9
Mean age category
<45 years	2	20.0	16.4	23.9	0.0011	98.2	<.01	2	8.4	3.0	16.3	0.0075	99.7	<.01	2	4.7	1.1	10.6	0.0068	99.7	<.01
45-48 years	2	20.4	19.4	21.4	0	0.0		1	7.4	6.4	8.5	—	—		1	3.1	2.4	3.8	—	—
50-56 years	3	28.3	27.1	29.6	<0.0001	0.9		1	30.1	27.3	33.1	—	—		1	14.9	12.7	17.2	—	—
NR	3	15.6	12.7	18.7	0.0013	91.9		2	4.3	1.1	9.4	0.0053	97.7		3	3.0	0.9	6.2	0.0047	97.7
Residence setting
Mixed rural/urban	3	21.9	15.7	28.9	0.0049	98.3	<.01	2	20.4	6.0	40.4	0.0252	99.4	.04	3	8.7	5.3	12.7	0.0033	97.5	<.01
Rural	5	18.1	16.1	20.3	0.0009	93.1		4	5.3	3.6	7.2	0.0016	95.6		4	2.4	1.5	3.6	0.0010	93.4
Urban	2	27.9	26.6	29.4	0	0.0		0	—	—-	—	—	—		0	—	—	—	—	—

Abbreviations: k, number of studies included in the meta-analysis of the pooled estimate; CI, confidence interval; τ2, a statistic provides an estimate of the between-study variance, in which a value of >1.0 suggests the presence of substantial statistical heterogeneity; I2, a statistic provides an estimate of the percentage of the variability in effect estimate that is due to heterogeneity rather than sampling error or chance differences where values of 25.0%, 50.0%, and 75.0% are interpreted as low, medium, and high heterogeneity, respectively; NR, not reported.

Test for subgroup differences, that is, Cochran’s Q test (χ2) where significant P < .10 suggests evidence of heterogeneity.

Significant p values are indicated in bold.

Measured Hypertension

Forest plots are available in Appendix 3. The pooled prevalence of measured HTN for the 10 studies is 21.1% (95% CI = 18.5-23.7; τ2 = 0.0026; I2 = 98%). The pooled prevalence of measured HTN for the 3 national studies is 18.4% (95% CI = 15.2-21.8; τ2 = 0.0014; I2 = 98%).

The results of the univariate meta-regression analyses showed that 3 factors significantly influenced the HTN prevalence and explained proportions of total between-study variance (ie, R2 statistic); these were proportions of women (QM = 7.8, degrees of freedom [df] = 1, P < .01, R2 = 31.8%), mean age (QM = 38.3, df = 3, P < .001, R2 = 67.1%), and residence setting (QM = 10.2, df = 2, P < .01, R2 = 29.5%).

Nine studies reported on the number of hypertensive subjects disaggregated by sex. The pooled prevalence of HTN among men is 26.4% (95% CI = 23.1-29.9; τ2 = 0.0033; I2 = 96%), which is higher than the overall prevalence. However, the pooled prevalence of HTN among women was lower, equaling 16.6% (95% CI = 13.4-20.0; τ2 = 0.0044; I2 = 98%).

The pooled prevalence of HTN among studies with a mean age ranging between 50 and 56 years is higher than the overall prevalence, equaling 28.3% (95% CI = 27.1-29.6; τ2 < 0.0001; I2 = 1%). With regard to residence settings, higher prevalence of HTN was found among studies undertaken in urban settings (27.9; 95% CI = 26.6-29.4; I2 = 0%) compared with mixed rural/urban settings (21.9%; 95% CI = 15.7-28.9; I2 = 98%) then rural settings (18.1%; 95% CI = 16.1-20.3; I2 = 93%).

Awareness of Hypertension

Forest plots are available in Appendix 4. Only 6 studies reported on the proportion of those aware of their HTN condition. The pooled prevalence of HTN awareness was 9.3% (95% CI = 5.3-14.3; τ2 = 0.0094; I2 = 99%).

Awareness was significantly associated with age and residence. A significant higher proportion of HTN awareness was reported among studies with oldest age group and those conducted in mixed rural/urban settings (49.0%; 95% CI = 43.6-54.4; τ2 = 0.002; I2 = 89%) compared with rural settings (27.5%; 95% CI = 21.7-33.6; τ2 = 0.0041; I2 = 92%).

Treatment of Hypertension

Forest plots are available in Appendix 5. Only 7 studies reported on the proportion of those treated for their HTN condition. The pooled prevalence of HTN treatment was 4.7% (95% CI = 2.6-7.3; τ2 = 0.0056; I2 = 99%). Similar to prevalence of HTN awareness, a significant higher proportion of HTN treatment was reported among studies with oldest age group and those conducted in mixed rural/urban settings (8.7%; 95% CI = 5.3-12.7; τ2 = 0.0033; I2 = 98%) compared with rural settings (2.4%; 95% CI = 1.5-3.6; τ2 = 0.0010; I2 = 93%).

Factors Associated With the Pooled Prevalence and Sex

Data are available in Appendix 6. Men has substantially higher odds than women for measured HTN (OR = 1.8; 95% CI = 1.6-2.1), HTN awareness (OR = 1.8; 95% CI = 1.5-2.1), and HTN treatment (OR = 1.8; 95% CI = 1.6-2.1). When stratified by categories for mean age and residence settings, only 2 subgroup analyses are significant. The association between male sex and measured HTN was higher for one study with mean age category 45 to 48 years (OR = 2.3; 95% CI = 2.0-2.7; τ2 = 0.0205; I2 = 76%), while the association between male sex and HTN awareness was higher for studies conducted in rural settings (OR = 1.9; 95% CI = 1.8-2.1; τ2 = 0.00216; I2 = 80%) compared with mixed rural/urban settings (OR = 1.5; 95% CI = 1.3-1.7).

Heterogeneity, Sensitivity Analyses, and Publication Bias

The included studies in the analyses of the pooled estimates showed a high heterogeneity. As a result of the regression analyses, the heterogeneity decreased when stratifying by sex, mean age category, and residence settings. To further identify specific sources of heterogeneity, more analysis for the prevalence of HTN excluded studies based on their smaller sample size or outlier results. The pooled prevalence calculated after the removal of 5 studies remained within ±10% of the original estimate. No evidence of publication bias was found based on the funnel plot asymmetry tests for all 3 summary measures (funnel plots are available in Appendix 7).

Discussion

To the best of our knowledge, this is the most comprehensive systematic review and meta-analysis on HTN prevalence in Vietnam. The pooled estimate for the prevalence of measured HTN in Vietnam, based on 10 studies published between 2005 and 2018, is 21.1%. However, the pooled estimate for the 3 studies with national surveys was lower (18.4%). These national samples can be more representative and reliable since they cover 66.6% of the total surveyed population included in this meta-analysis. A meta-analysis on the prevalence of HTN in LMICs (2001-2015) found an overall prevalence of 32.3% (29.4-35.3) and 35.5% (32.2-39.4) in East Asia and Pacific, respectively, based on 33 articles from China (n = 22), Vietnam (n = 5, all included in our analysis), Malaysia (n = 4), Thailand (n = 1), and Federated States of Micronesia (n = 1).[5] Another meta-analysis for the prevalence of HTN in Chinese cities (2002-2010) had an estimate of 21.5% (19.4% to 23.6%).[43] Our estimate for the prevalence of HTN in Vietnam appears to be lower than estimates reported in other countries of East Asia and Pacific. One explanation may be the observed differences in conducting surveys and measurement procedures, which have either changed over time or have not followed one specific guideline. Additionally, while most studies used digital measurement devices, only 2 with one of the national studies have used mercury sphygmomanometer. However, the pooled prevalence was not significantly associated with the use of digital or mercury measurement device.

Residence settings have significantly influenced the pooled prevalence of measured HTN and HTN awareness and treatment. There was a higher prevalence of measured HTN in urban and mixed rural/urban compared with separate rural settings; this is similar to findings from the meta-analysis of LMICs[5] and the time trends analysis of Vietnam.[10] Furthermore, the proportion of hypertensive subjects who are aware of their condition was significantly higher among mixed rural/urban compared with rural settings. The time trends analysis found an increased prevalence of HTN awareness in both rural and urban areas between 2001 and 2009; however, the change in HTN awareness in urban areas and HTN control in rural areas had slower progress.[10] Our results regarding the lower awareness of HTN in rural settings may reflect a limited detection of HTN in the rural areas of the country compared with urban areas.

As expected, the odds of measured HTN among men was higher than the odds of HTN among women. This sex difference was also affected by residence settings with higher odds of HTN among men living in rural settings, while the overall prevalence for both sexes is higher in urban settings. This is an unusual pattern that was also reported in the individual studies. Further research may focus on explaining this sex difference in the prevalence of HTN in Vietnam.

The quality assessment has excluded 2 national surveys[18,19] due to a low response rate. The data collection date for these 2 surveys was 2002 and 2009-2010, respectively. In addition, both studies had good sample sizes (n = 77 758 and n = 14 706, respectively). The 2 studies reported a lower overall prevalence of HTN; however, both studies showed a higher prevalence among men compared with women. Furthermore, the latest study[19] explored regional differences in the prevalence of HTN with the highest prevalence in West Highland (Dak Lak province) and Mekong River Delta (Can Tho province) and the lowest prevalence in Red River Delta (Ha Noi) and North Central (Hue). Our analysis could not look at regional differences because half the included studies are from 2 regions and the national ones did not report their data by region.

Strengths and Limitations

We reported results from only high-quality studies, and there was no evidence of publication bias. We also reported results for both random and fixed models, which showed similar results in pooled estimates; however, they differed in the 95% CIs. Heterogeneity among studies was high; its causes include differences in sample characteristics and standardization of blood pressure measurement procedures including devices and number of readings. Although we tried to lower the heterogeneity by conducting meta-regression and subgroup analysis, we were limited to the factors that could be included, especially with only 7 studies with a primary focus on HTN. For example, the age range was different in included studies; when stratifying by age groups, we had a smaller number of studies. Few studies reported on the awareness, treatment, and control of HTN. There was enough number of studies to perform an analysis on HTN awareness and treatment; a smaller number of studies reported estimates for control of HTN. The studies covered different parts of the country for both rural and urban populations. However, representation is questionable since some regions were only covered by the national surveys, with no individual studies conducted there.

Conclusion

Hypertension is a significant public health problem in Vietnam. Almost 1 in 5 people may have HTN. Awareness and treatment were much lower in rural areas. There is a need to strengthen primary and secondary prevention measures in addition to management activities to reduce morbidity and mortality of HTN, especially in rural areas.

Click here for additional data file.

Supplemental material, Appendix_1_Search_Strategy for Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis by Lana Meiqari, Dirk Essink, Pamela Wright and Fedde Scheele in Asia Pacific Journal of Public Health

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Supplemental material, Appendix_2_Quality_Assessment_Final for Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis by Lana Meiqari, Dirk Essink, Pamela Wright and Fedde Scheele in Asia Pacific Journal of Public Health

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Supplemental material, Appendix_3_Forest_Plot_Measured_HTN for Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis by Lana Meiqari, Dirk Essink, Pamela Wright and Fedde Scheele in Asia Pacific Journal of Public Health

Click here for additional data file.

Supplemental material, Appendix_4_Forest_Plot_HTN_Awareness for Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis by Lana Meiqari, Dirk Essink, Pamela Wright and Fedde Scheele in Asia Pacific Journal of Public Health

Click here for additional data file.

Supplemental material, Appendix_5_Forest_Plot_HTN_Treatment for Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis by Lana Meiqari, Dirk Essink, Pamela Wright and Fedde Scheele in Asia Pacific Journal of Public Health

Click here for additional data file.

Supplemental material, Appendix_6_OR_HTN_Sex for Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis by Lana Meiqari, Dirk Essink, Pamela Wright and Fedde Scheele in Asia Pacific Journal of Public Health

Click here for additional data file.

Supplemental material, Appendix_7_Funnel_Plots for Prevalence of Hypertension in Vietnam: A Systematic Review and Meta-Analysis by Lana Meiqari, Dirk Essink, Pamela Wright and Fedde Scheele in Asia Pacific Journal of Public Health