Literature DB >> 30634187

Child-Pugh Classification: Time to Abandon?

Beverley Kok1, Juan G Abraldes1.   

Abstract

The Child-Pugh classification is one of the commonest and oldest bedside tools utilized in estimating prognosis in patients with cirrhosis. However, its usage as a risk prediction tool or indeed a decision-making tool should be revisited. In this review, we discuss some inherent issues with the Child-Pugh classification and present a few contexts in which the current usage of Child-Pugh warrants reassessment, elaborating on its utility in acute variceal bleeding, specifically its role in decision-making on early transjugular intrahepatic portosystemic shunt, as well as its use in the context of hepatocellular carcinoma and drug development and dose adjustment. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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Year:  2019        PMID: 30634187     DOI: 10.1055/s-0038-1676805

Source DB:  PubMed          Journal:  Semin Liver Dis        ISSN: 0272-8087            Impact factor:   6.115


  14 in total

Review 1.  Therapies for hepatocellular carcinoma: overview, clinical indications, and comparative outcome evaluation-part one: curative intention.

Authors:  Joseph H Yacoub; Christine C Hsu; Thomas M Fishbein; David Mauro; Andrew Moon; Aiwu R He; Mustafa R Bashir; Lauren M B Burke
Journal:  Abdom Radiol (NY)       Date:  2021-04-09

2.  A detailed assessment of liver function in patients with hepatocellular carcinoma via the modified albumin-bilirubin (mALBI) grade.

Authors:  Cheng-Rui Zhong; Ji-Liang Qiu; Yi-Chuan Yuan; Zhi-Yu Qiu; Kai Li; Chen-Wei Wang; Yun-Xing Shi; Ke-Ren Li; Zhu Lin; Zhen-Kun Huang; Wei He; Bin-Kui Li; Yun-Fei Yuan
Journal:  Am J Cancer Res       Date:  2022-06-15       Impact factor: 5.942

3.  Hepatocellular carcinoma grading and recurrence prediction using T1 mapping on gadolinium-ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging.

Authors:  Xiali Qin; Tengfei Yang; Zhongkui Huang; Liling Long; Zhipeng Zhou; Wenmei Li; Yinjuan Gao; Mengzhu Wang; Xiaoyong Zhang
Journal:  Oncol Lett       Date:  2019-07-04       Impact factor: 2.967

4.  Albumin-bilirubin index and platelet-albumin-bilirubin index contribute to identifying survival benefit candidates in patients with hepatocellular carcinoma and Child-Pugh grade A undergoing transcatheter arterial chemoembolization with sorafenib treatment.

Authors:  Keshu Hu; Jia Yuan; Bei Tang; Feng Zhang; Shenxin Lu; Rongxin Chen; Lan Zhang; Zhenggang Ren; Xin Yin
Journal:  Ann Transl Med       Date:  2021-02

5.  CT radiomics nomogram for the preoperative prediction of severe post-hepatectomy liver failure in patients with huge (≥ 10 cm) hepatocellular carcinoma.

Authors:  Fei Xiang; Xiaoyuan Liang; Lili Yang; Xingyu Liu; Sheng Yan
Journal:  World J Surg Oncol       Date:  2021-12-12       Impact factor: 2.754

Review 6.  Systemic Therapy for Hepatocellular Carcinoma: Current Updates and Outlook.

Authors:  Yinjie Fan; Hang Xue; Huachuan Zheng
Journal:  J Hepatocell Carcinoma       Date:  2022-03-30

7.  Predictive utility of the C-reactive protein to albumin ratio in early allograft dysfunction in living donor liver transplantation: A retrospective observational cohort study.

Authors:  Jaesik Park; Soo Jin Lim; Ho Joong Choi; Sang Hyun Hong; Chul Soo Park; Jong Ho Choi; Min Suk Chae
Journal:  PLoS One       Date:  2019-12-10       Impact factor: 3.240

8.  The Prognosis Analysis of Liver Cirrhosis with Acute Variceal Bleeding and Validation of Current Prognostic Models: A Large Scale Retrospective Cohort Study.

Authors:  Yan Zhao; Mudan Ren; Guifang Lu; Xinlan Lu; Yan Yin; Dan Zhang; Xin Wang; Wenhui Ma; Yarui Li; Guohong Cai; Yiguang Lin; Shuixiang He
Journal:  Biomed Res Int       Date:  2020-08-16       Impact factor: 3.411

9.  Alteration of prognostic efficacy of albumin-bilirubin grade and Child-Pugh score according to liver fibrosis in hepatocellular carcinoma patients with Child-Pugh A following hepatectomy.

Authors:  Tatsunori Miyata; Yo-Ichi Yamashita; Kota Arima; Takaaki Higashi; Hiromitsu Hayashi; Katsunori Imai; Hidetoshi Nitta; Akira Chikamoto; Toru Beppu; Hideo Baba
Journal:  Ann Gastroenterol Surg       Date:  2021-09-19

10.  A novel preoperative predictive model of 90-day mortality after liver resection for huge hepatocellular carcinoma.

Authors:  Yue Yin; Jian-Wen Cheng; Fei-Yu Chen; Xu-Xiao Chen; Xin Zhang; Ao Huang; De-Zhen Guo; Yu-Peng Wang; Ya Cao; Jia Fan; Jian Zhou; Xin-Rong Yang
Journal:  Ann Transl Med       Date:  2021-05
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