Annekatrin Rickmann1,2, Silke Wahl3, Alisa Katsen-Globa4, Peter Szurman3,5. 1. Eye Clinic Sulzbach, Knappschaft Hospital Saar, An der Klinik 10, 66280, Sulzbach, Saarland, Germany. annekatrinrick@gmail.com. 2. Fraunhofer Institute for Biomedical Engineering, Sulzbach, Saarland, Germany. annekatrinrick@gmail.com. 3. Eye Clinic Sulzbach, Knappschaft Hospital Saar, An der Klinik 10, 66280, Sulzbach, Saarland, Germany. 4. Fraunhofer Institute for Biomedical Engineering, Sulzbach, Saarland, Germany. 5. University Eye Clinic Tuebingen, Centre for Ophthalmology, Tuebingen, Germany.
Abstract
PURPOSE: The aim of this study was to investigate the clinical outcome after standardized DMEK using a glass injector. METHODS: A total of 254 patients undergoing DMEK surgery using a disposable DMEK borosilicate glass cartridge system were included in this retrospective study. The mean follow-up time was 13.2 months (SD ± 8.1, range 6-36 months). The used glass cartridge system has an aperture diameter of 1.6 mm and a posterior loading orifice of 4.29 mm. Scanning electron microscopy (SEM) was used for estimation of the surface relief of the glass cartridge and comparison with a standard plastic injector cartridge. RESULTS: Mean endothelial cell count of donor grafts was 2465 cells/mm2 (SD ± 199). After 6 weeks of DMEK endothelial cell count decreased by - 28.6% to 1759 cells/mm2 (SD ± 435) (Wilcoxon p = 0.001) and remained stable at the final follow-up at 1735 cells/mm2 (SD ± 442) (Wilcoxon p = 0.89). SEM showed smoother surface of the glass cartridge in comparison with a plastic cartridge. CONCLUSION: This study showed that this simple and effective DMEK cartridge seems to be a safe and viable device for minimized graft manipulation during DMEK surgery.
PURPOSE: The aim of this study was to investigate the clinical outcome after standardized DMEK using a glass injector. METHODS: A total of 254 patients undergoing DMEK surgery using a disposable DMEKborosilicate glass cartridge system were included in this retrospective study. The mean follow-up time was 13.2 months (SD ± 8.1, range 6-36 months). The used glass cartridge system has an aperture diameter of 1.6 mm and a posterior loading orifice of 4.29 mm. Scanning electron microscopy (SEM) was used for estimation of the surface relief of the glass cartridge and comparison with a standard plastic injector cartridge. RESULTS: Mean endothelial cell count of donor grafts was 2465 cells/mm2 (SD ± 199). After 6 weeks of DMEK endothelial cell count decreased by - 28.6% to 1759 cells/mm2 (SD ± 435) (Wilcoxon p = 0.001) and remained stable at the final follow-up at 1735 cells/mm2 (SD ± 442) (Wilcoxon p = 0.89). SEM showed smoother surface of the glass cartridge in comparison with a plastic cartridge. CONCLUSION: This study showed that this simple and effective DMEK cartridge seems to be a safe and viable device for minimized graft manipulation during DMEK surgery.
Authors: Jack Parker; Martin Dirisamer; Miguel Naveiras; Lisanne Ham; Jacqueline van der Wees; Gerrit R J Melles Journal: Am J Ophthalmol Date: 2011-06 Impact factor: 5.258
Authors: K Droutsas; A Lazaridis; G D Kymionis; K Chatzistefanou; M M Moschos; C Koutsandrea; W Sekundo Journal: Eye (Lond) Date: 2017-11-17 Impact factor: 3.775
Authors: Frederico P Guerra; Arundhati Anshu; Marianne O Price; Arthur W Giebel; Francis W Price Journal: Ophthalmology Date: 2011-08-27 Impact factor: 12.079
Authors: Annekatrin Rickmann; Karl Boden; André M Trouvain; Lisa J Müller; Catheline Bocqué; Sebastian Thaler; Peter Szurman Journal: Int Ophthalmol Date: 2021-10-31 Impact factor: 2.031
Authors: Annekatrin Rickmann; Karl Boden; Silke Wahl; Andre Trouvain; Andre Schulz; Peter Szurman Journal: Int Ophthalmol Date: 2021-10-21 Impact factor: 2.031