| Literature DB >> 30602764 |
Jonathan Jung1,2, Hu Zeng3,4, Tiffany Horng5,6.
Abstract
Recent studies indicate that cellular metabolism plays a key role in supporting immune cell maintenance and development. Here, we review how metabolism guides immune cell activation and differentiation to distinct cellular states, and how differential regulation of metabolism allows for context-dependent support during activation and lineage commitment. We discuss emerging principles of metabolic support of immune cell function in physiology and disease, as well as their general relevance to the field of cell biology.Entities:
Mesh:
Year: 2019 PMID: 30602764 DOI: 10.1038/s41556-018-0217-x
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824