Literature DB >> 34773132

Regulation of energy metabolism in human pluripotent stem cells.

Weiwei Liu1,2, Guokai Chen3,4.   

Abstract

All living organisms need energy to carry out their essential functions. The importance of energy metabolism is increasingly recognized in human pluripotent stem cells. Energy production is not only essential for cell survival and proliferation, but also critical for pluripotency and cell fate determination. Thus, energy metabolism is an important target in cellular regulation and stem cell applications. In this review, we will discuss key factors that influence energy metabolism and their association with stem cell functions.
© 2021. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

Entities:  

Keywords:  Glycolysis; Insulin; Nutrient; Oxidative phosphorylation; Oxygen; pH

Mesh:

Year:  2021        PMID: 34773132     DOI: 10.1007/s00018-021-04016-0

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN: 1420-682X            Impact factor:   9.261


  112 in total

Review 1.  FoxOs at the crossroads of cellular metabolism, differentiation, and transformation.

Authors:  Domenico Accili; Karen C Arden
Journal:  Cell       Date:  2004-05-14       Impact factor: 41.582

2.  A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.

Authors:  Sébastien Bonnet; Stephen L Archer; Joan Allalunis-Turner; Alois Haromy; Christian Beaulieu; Richard Thompson; Christopher T Lee; Gary D Lopaschuk; Lakshmi Puttagunta; Sandra Bonnet; Gwyneth Harry; Kyoko Hashimoto; Christopher J Porter; Miguel A Andrade; Bernard Thebaud; Evangelos D Michelakis
Journal:  Cancer Cell       Date:  2007-01       Impact factor: 31.743

3.  Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium.

Authors:  David E Buchholz; Britney O Pennington; Roxanne H Croze; Cassidy R Hinman; Peter J Coffey; Dennis O Clegg
Journal:  Stem Cells Transl Med       Date:  2013-04-18       Impact factor: 6.940

4.  Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice.

Authors:  Ebbe Boedtkjer; Jeppe Praetorius; Vladimir V Matchkov; Edgaras Stankevicius; Susie Mogensen; Annette C Füchtbauer; Ulf Simonsen; Ernst-Martin Füchtbauer; Christian Aalkjaer
Journal:  Circulation       Date:  2011-09-26       Impact factor: 29.690

5.  Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis.

Authors:  M Alvarez-Tejado; S Naranjo-Suarez; C Jiménez; A C Carrera; M O Landázuri; L del Peso
Journal:  J Biol Chem       Date:  2001-04-09       Impact factor: 5.157

6.  A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.

Authors:  Matthew J Birket; Adam L Orr; Akos A Gerencser; David T Madden; Cathy Vitelli; Andrzej Swistowski; Martin D Brand; Xianmin Zeng
Journal:  J Cell Sci       Date:  2011-02-01       Impact factor: 5.285

7.  Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death.

Authors:  R L Aft; F W Zhang; D Gius
Journal:  Br J Cancer       Date:  2002-09-23       Impact factor: 7.640

8.  Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.

Authors:  Bryce W Carey; Lydia W S Finley; Justin R Cross; C David Allis; Craig B Thompson
Journal:  Nature       Date:  2014-12-10       Impact factor: 49.962

9.  Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency.

Authors:  Elena Carbognin; Riccardo M Betto; Maria E Soriano; Austin G Smith; Graziano Martello
Journal:  EMBO J       Date:  2016-02-22       Impact factor: 11.598

10.  HMGA1 is a novel transcriptional regulator of the FoxO1 gene.

Authors:  Biagio Arcidiacono; Eusebio Chiefari; Sebastiano Messineo; Francesco L Bilotta; Ida Pastore; Domenica M Corigliano; Daniela P Foti; Antonio Brunetti
Journal:  Endocrine       Date:  2017-10-19       Impact factor: 3.633

View more
  1 in total

1.  1H NMR Metabolite Monitoring during the Differentiation of Human Induced Pluripotent Stem Cells Provides New Insights into the Molecular Events That Regulate Embryonic Chondrogenesis.

Authors:  Ashley Coope; Zain Ghanameh; Olivia Kingston; Carl M Sheridan; Richard Barrett-Jolley; Marie M Phelan; Rachel A Oldershaw
Journal:  Int J Mol Sci       Date:  2022-08-17       Impact factor: 6.208

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.