Literature DB >> 30539223

Arthroscopic treatment of osteochondral knee defects with resorbable biphasic synthetic scaffold: clinical and radiological results and long-term survival analysis.

Riccardo D'Ambrosi1, Francesco Giacco2, Vincenza Ragone3, Nicola Ursino2.   

Abstract

PURPOSE: The aim of our study is to evaluate the long-term results in patients treated with a fully arthroscopic TruFit system for osteochondral lesions of the femoral condyle, analyzing the clinical and radiological outcomes, survival rate, complications, and correlations.
METHODS: The study included all patients treated with the TruFit system with a full-thickness focal lesion of the knee cartilage (grade IV according to the ICRS classification), entirely arthroscopically with a minimum follow-up of five years. All patients were evaluated clinically prior to surgery (T0) and at two consecutive follow-ups (T1 36.4 ± 17.03 months and T2 101.63 ± 19.02 months), using the Knee Injury and Osteoarthritis Outcome Score (KOOS) and the Hospital for Special Surgery Score (HSS). At the final follow-up, the magnetic resonance imaging (MRI) was evaluated by two orthopaedists using the magnetic resonance observation of cartilage repair tissue (MOCART) score.
RESULTS: The sample was formed of 21 patients, of which 14 were males (67%) and 7 females (33%), with a mean age of 51.29 ± 10.70. Of the 21 patients, two underwent prosthetic knee replacement at 24 and 65 months, respectively. At T0, the HSS and the KOOS score were, respectively, 60.71 ± 11.62 and 57.71 ± 6.11. For both clinical values, a significant improvement was noted between T0 and T1 (p < 0.05) and between T0 and T2 (p < 0.05). At the final follow-up, the MOCART value was found to be 45.78 ± 5.27.
CONCLUSIONS: The study results highlighted the safety and potential of the arthroscopic TruFit system procedure, which offered a good clinical outcome with stable results at long-term follow-up although we found no correlations between the MRI and clinical results.

Entities:  

Keywords:  Arthroscopy; Cartilage; MOCART; Osteochondral defects; Scaffold; The Kaplan-Meier survival analysis

Mesh:

Substances:

Year:  2018        PMID: 30539223     DOI: 10.1007/s00264-018-4270-7

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  23 in total

1.  Development of the Italian version of the knee injury and osteoarthritis outcome score for patients with knee injuries: cross-cultural adaptation, dimensionality, reliability, and validity.

Authors:  M Monticone; S Ferrante; S Salvaderi; B Rocca; V Totti; C Foti; G S Roi
Journal:  Osteoarthritis Cartilage       Date:  2012-01-10       Impact factor: 6.576

2.  Magnetic resonance observation of cartilage repair tissue (MOCART) for the evaluation of autologous chondrocyte transplantation: determination of interobserver variability and correlation to clinical outcome after 2 years.

Authors:  Stefan Marlovits; Philipp Singer; Philip Zeller; Irena Mandl; Jörg Haller; Siegfried Trattnig
Journal:  Eur J Radiol       Date:  2005-10-03       Impact factor: 3.528

3.  Does arthroscopic abrasion arthroplasty promote cartilage regeneration in osteoarthritic knees with eburnation? A prospective study of high tibial osteotomy with abrasion arthroplasty versus high tibial osteotomy alone.

Authors:  S Akizuki; Y Yasukawa; T Takizawa
Journal:  Arthroscopy       Date:  1997-02       Impact factor: 4.772

4.  Delayed incorporation of a TruFit plug: perseverance is recommended.

Authors:  Michael Robert Carmont; Richard Carey-Smith; Adnan Saithna; Manpreet Dhillon; Peter Thompson; Tim Spalding
Journal:  Arthroscopy       Date:  2009-07       Impact factor: 4.772

5.  Biphasic bioresorbable scaffold (TruFit®) in knee osteochondral defects: 3-T MRI evaluation of osteointegration in patients with a 5-year minimum follow-up.

Authors:  G Bugelli; F Ascione; G Dell'Osso; V Zampa; S Giannotti
Journal:  Musculoskelet Surg       Date:  2017-11-21

Review 6.  Layered Scaffolds for Osteochondral Tissue Engineering.

Authors:  Diana Ribeiro Pereira; Rui L Reis; J Miguel Oliveira
Journal:  Adv Exp Med Biol       Date:  2018       Impact factor: 2.622

7.  Synthetic resorbable scaffolds for the treatment of isolated patellofemoral cartilage defects in young patients: magnetic resonance imaging and clinical evaluation.

Authors:  Nayana Joshi; Mercè Reverte-Vinaixa; Eugenio Wenceslao Díaz-Ferreiro; Rosa Domínguez-Oronoz
Journal:  Am J Sports Med       Date:  2012-04-05       Impact factor: 6.202

8.  Subchondral chitosan/blood implant-guided bone plate resorption and woven bone repair is coupled to hyaline cartilage regeneration from microdrill holes in aged rabbit knees.

Authors:  J Guzmán-Morales; C-H Lafantaisie-Favreau; G Chen; C D Hoemann
Journal:  Osteoarthritis Cartilage       Date:  2013-12-19       Impact factor: 6.576

Review 9.  Is magnetic resonance imaging reliable in predicting clinical outcome after articular cartilage repair of the knee? A systematic review and meta-analysis.

Authors:  Tommy S de Windt; Goetz H Welsch; Mats Brittberg; Lucienne A Vonk; Stefan Marlovits; Siegfried Trattnig; Daniel B F Saris
Journal:  Am J Sports Med       Date:  2013-01-30       Impact factor: 6.202

10.  Articular cartilage repair using a resorbable matrix scaffold.

Authors:  Riley J Williams; Seth C Gamradt
Journal:  Instr Course Lect       Date:  2008
View more
  4 in total

1.  Treatment of focal chondral lesions in the knee using a synthetic scaffold plug: Long-term clinical and radiological results.

Authors:  Faiz S Shivji; Aadil Mumith; Sam Yasen; Joel Tk Melton; Adrian J Wilson
Journal:  J Orthop       Date:  2020-01-14

2.  Articular cartilage delamination at eight years following cellular-based repair procedures: a case reports.

Authors:  Alberto Gobbi; John G Lane; Macarena Morales; Riccardo D'Ambrosi
Journal:  J Exp Orthop       Date:  2022-09-07

3.  Synthetic Biphasic Scaffolds versus Microfracture for Articular Cartilage Defects of the Knee: A Retrospective Comparative Study.

Authors:  Dean Wang; Danyal H Nawabi; Aaron J Krych; Kristofer J Jones; Joseph Nguyen; Ameer M Elbuluk; Nadja A Farshad-Amacker; Hollis G Potter; Riley J Williams
Journal:  Cartilage       Date:  2020-02-11       Impact factor: 3.117

Review 4.  Multi-layer cell-free scaffolds for osteochondral defects of the knee: a systematic review and meta-analysis of clinical evidence.

Authors:  Angelo Boffa; Luca Solaro; Alberto Poggi; Luca Andriolo; Davide Reale; Alessandro Di Martino
Journal:  J Exp Orthop       Date:  2021-07-30
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.