G Bugelli1, F Ascione2, G Dell'Osso3, V Zampa4, S Giannotti5. 1. Humanitas Clinical and Research Center, Via Manzoni 56, 20089, Rozzano, Milan, Italy. bugeposta@hotmail.it. 2. Orthopedics and Traumatology Department, SUN, Naples, Italy. 3. Orthopedics and Traumatology Department, Ospedale San Luca, Lucca, Italy. 4. Department of Diagnostic and Interventional Radiology, University of Pisa, Pisa, Italy. 5. Orthopedics and Traumatology Department, University of Siena, Siena, Italy.
Abstract
PURPOSE: The aim of this study is to follow morphological imaging characteristics and osteointegration of TruFit® bone graft substitute (BGS) plugs in cases of chondral and osteochondral defects of the articular surface of the knee joint, using high-quality cartilage-sensitive 3-T magnetic resonance imaging (MRI), linked to clinical outcomes. METHODS: The MRI was used to assess osteointegration and biological evolution of the TruFit® BGS plugs in cases with minimum 5-year follow-up: The TruFit® plug was used in 46 patients for a total of 47 cases with mean age of 57.89 (range 32-80). In this study, we reviewed only the cases with minimum follow-up of 5 years: 5 patients with mean age 64.4 years (minimum 38, maximum 80). The mean follow-up was 71 months (range 63-77). Patients were evaluated clinically, with Lysholm Knee Scoring Scale and MOCART Scale. RESULTS: 3-T MRI, which is preferable to 1.5 T for the better signal-to-noise ratio, contrast and the ability to acquire morphological images at higher spatial resolution, shows a satisfactory integration of bone scaffolds in studied cases for more than 5 years and a satisfactory restoration of the articular cartilage, with the exception of a case of which we still have to consider the factors age, type of lesion and the relationship between the plugs implanted. CONCLUSION: Clinical and radiological results significantly improve in a longer follow-up time.
PURPOSE: The aim of this study is to follow morphological imaging characteristics and osteointegration of TruFit® bone graft substitute (BGS) plugs in cases of chondral and osteochondral defects of the articular surface of the knee joint, using high-quality cartilage-sensitive 3-T magnetic resonance imaging (MRI), linked to clinical outcomes. METHODS: The MRI was used to assess osteointegration and biological evolution of the TruFit® BGS plugs in cases with minimum 5-year follow-up: The TruFit® plug was used in 46 patients for a total of 47 cases with mean age of 57.89 (range 32-80). In this study, we reviewed only the cases with minimum follow-up of 5 years: 5 patients with mean age 64.4 years (minimum 38, maximum 80). The mean follow-up was 71 months (range 63-77). Patients were evaluated clinically, with Lysholm Knee Scoring Scale and MOCART Scale. RESULTS: 3-T MRI, which is preferable to 1.5 T for the better signal-to-noise ratio, contrast and the ability to acquire morphological images at higher spatial resolution, shows a satisfactory integration of bone scaffolds in studied cases for more than 5 years and a satisfactory restoration of the articular cartilage, with the exception of a case of which we still have to consider the factors age, type of lesion and the relationship between the plugs implanted. CONCLUSION: Clinical and radiological results significantly improve in a longer follow-up time.
Authors: Aad A M Dhollander; Koen Liekens; Karl F Almqvist; René Verdonk; Stijn Lambrecht; Dirk Elewaut; Gust Verbruggen; Peter C M Verdonk Journal: Arthroscopy Date: 2011-10-20 Impact factor: 4.772
Authors: Renato Andrade; Joni Nunes; Betina B Hinckel; Jordan Gruskay; Sebastiano Vasta; Ricardo Bastos; J Miguel Oliveira; Rui L Reis; Andreas H Gomoll; João Espregueira-Mendes Journal: Cartilage Date: 2019-12-17 Impact factor: 3.117
Authors: Chengchong Ai; Yee Han Dave Lee; Xuan Hao Tan; Si Heng Sharon Tan; James Hoi Po Hui; James Cho-Hong Goh Journal: J Orthop Translat Date: 2021-10-11 Impact factor: 5.191
Authors: Dean Wang; Danyal H Nawabi; Aaron J Krych; Kristofer J Jones; Joseph Nguyen; Ameer M Elbuluk; Nadja A Farshad-Amacker; Hollis G Potter; Riley J Williams Journal: Cartilage Date: 2020-02-11 Impact factor: 3.117