Literature DB >> 30506182

Prospective evaluation of paravaginal defect repair with and without apical suspension: a 6-month postoperative follow-up with MRI, clinical examination, and questionnaires.

Louise T S Arenholt1,2, Bodil Ginnerup Pedersen3, Karin Glavind4, Susanne Greisen5, Karl M Bek5, Marianne Glavind-Kristensen5.   

Abstract

INTRODUCTION AND HYPOTHESIS: Paravaginal defect (PVD) has been suggested as one of the main contributors to the development of prolapse in the anterior vaginal wall (AVW). We aimed to evaluate the descent of pelvic organs, presence of vaginal H configuration, and pubococcygeus (PC) muscle defect by pelvic magnetic resonance imaging (MRI), together with subjective symptoms of prolapse, before and 6 months after PVD repair. We also aimed to evaluate risk factors of recurrence.
METHODS: Fifty women with PVD diagnosed by gynecological examination and scheduled for vaginal PVD repair were planned for enrollment. Preoperatively and 6 months postoperatively, subjective symptoms were evaluated using the International Consultation on Incontinence Questionnaire-Vaginal Symptoms (ICIQ-VS) together with MRI of the pelvis to evaluate defects in the PC muscle, vaginal shape, and pelvic organ descent.
RESULTS: Forty-six women completed the study. Twenty had PVD repair alone, whereas 26 also had concomitant surgery performed. Prolapse grade, subjective symptoms, sexual problems, and quality of life (QoL) were significantly improved at follow-up. Missing vaginal H configuration was observed in 21 women before operation and was correlated with PC muscle defect. Recurrence rate was 39%, and significantly more women with recurrence had PC muscle defects and missing H configuration.
CONCLUSION: Vaginal PVD repair alone or combined with concomitant surgery significantly reduces objective prolapse and subjective symptoms. We could not demonstrate MRI findings of missing H configuration to be a sign of PVD but, rather, a sign of defect in the PC muscle. Risk of recurrence is significantly higher in women with major PC muscle defects and missing H configuration.

Entities:  

Keywords:  Levator ani defects; MRI; PVD; Paravaginal defect; Paravaginal defect repair; Pubococcygeus defect

Mesh:

Year:  2018        PMID: 30506182     DOI: 10.1007/s00192-018-3807-z

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  29 in total

1.  The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction.

Authors:  R C Bump; A Mattiasson; K Bø; L P Brubaker; J O DeLancey; P Klarskov; B L Shull; A R Smith
Journal:  Am J Obstet Gynecol       Date:  1996-07       Impact factor: 8.661

2.  Interrater reliability of assessing levator ani muscle defects with magnetic resonance images.

Authors:  Daniel M Morgan; Wolfgang Umek; Tamara Stein; Yvonne Hsu; Kenneth Guire; John O L DeLancey
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2006-10-17

3.  Outcome assessment with blinded versus unblinded POP-Q exams.

Authors:  Danielle D Antosh; Cheryl B Iglesia; Sonali Vora; Andrew I Sokol
Journal:  Am J Obstet Gynecol       Date:  2011-07-20       Impact factor: 8.661

4.  Incidence and lifetime risk of pelvic organ prolapse surgery in Denmark from 1977 to 2009.

Authors:  Ea Løwenstein; Bent Ottesen; Helga Gimbel
Journal:  Int Urogynecol J       Date:  2014-05-20       Impact factor: 2.894

Review 5.  Paravaginal defect: anatomy, clinical findings, and imaging.

Authors:  Louise T S Arenholt; Bodil Ginnerup Pedersen; Karin Glavind; Marianne Glavind-Kristensen; John O L DeLancey
Journal:  Int Urogynecol J       Date:  2016-09-17       Impact factor: 2.894

6.  Translation and validation of the International Consultation on Incontinence Questionnaire Vaginal Symptoms (ICIQ-VS): the Danish version.

Authors:  Louise Thomsen Schmidt Arenholt; Marianne Glavind-Kristensen; Henrik Bøggild; Karin Glavind
Journal:  Int Urogynecol J       Date:  2018-01-10       Impact factor: 2.894

Review 7.  Translabial US and Dynamic MR Imaging of the Pelvic Floor: Normal Anatomy and Dysfunction.

Authors:  Luciana P Chamié; Duarte Miguel Ferreira Rodrigues Ribeiro; Angela H M Caiado; Gisele Warmbrand; Paulo C Serafini
Journal:  Radiographics       Date:  2018 Jan-Feb       Impact factor: 5.333

8.  Accuracy of clinical assessment of paravaginal defects in women with anterior vaginal wall prolapse.

Authors:  M D Barber; G W Cundiff; A C Weidner; K W Coates; R C Bump; W A Addison
Journal:  Am J Obstet Gynecol       Date:  1999-07       Impact factor: 8.661

9.  Paravaginal defects: prevalence and accuracy of preoperative detection.

Authors:  Jeffrey L Segal; Brett J Vassallo; Steven D Kleeman; William A Silva; Mickey M Karram
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2004-07-01

Review 10.  Risk factors for pelvic organ prolapse and its recurrence: a systematic review.

Authors:  Tineke F M Vergeldt; Mirjam Weemhoff; Joanna IntHout; Kirsten B Kluivers
Journal:  Int Urogynecol J       Date:  2015-05-13       Impact factor: 2.894

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  4 in total

1.  Trans-obturator cystocele repair of level 2 paravaginal defect.

Authors:  Vladimir Kalis; Veronika Kovarova; Zdenek Rusavy; Khaled M Ismail
Journal:  Int Urogynecol J       Date:  2020-06-03       Impact factor: 2.894

Review 2.  Is levator ani avulsion a risk factor for prolapse recurrence? A systematic review and meta-analysis.

Authors:  Ellen Yeung; Eva Malacova; Christopher Maher
Journal:  Int Urogynecol J       Date:  2022-05-10       Impact factor: 1.932

3.  Transvaginal and transobturator autologous vaginal tape cystocele treatment: About an uncommon case.

Authors:  Amine Slaoui; Aziz Slaoui; Yassir Himmi; Babty Mouftah; Ayoub Mamad; Tarik Karmouni; Khalid El Khader; Aziz Baydada; Abdellatif Koutani; Ahmed Iben Atyya
Journal:  Int J Surg Case Rep       Date:  2022-05-16

4.  Methods for the defining mechanisms of anterior vaginal wall descent (DEMAND) study.

Authors:  Pamela A Moalli; Shaniel T Bowen; Steven D Abramowitch; Mark E Lockhart; Michael Ham; Michael Hahn; Alison C Weidner; Holly E Richter; Charles R Rardin; Yuko M Komesu; Heidi S Harvie; Beri M Ridgeway; Donna Mazloomdoost; Amanda Shaffer; Marie G Gantz
Journal:  Int Urogynecol J       Date:  2020-09-01       Impact factor: 2.894

  4 in total

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