Literature DB >> 30398387

Poly(Thioketal Urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation.

Madison A P McGough1,2, Stefanie M Shiels3, Lauren A Boller1,2, Katarzyna J Zienkiewicz4, Craig L Duvall1, Joseph C Wenke3, Scott A Guelcher1,2,4.   

Abstract

IMPACT STATEMENT: The development of autograft extenders is a significant clinical need in bone tissue engineering. We report new settable poly(thioketal urethane)-based autograft extenders that have bone-like mechanical properties and handling properties comparable to calcium phosphate bone cements. These settable autograft extenders remodeled to form new bone in a biologically stringent intertransverse process model of bone formation that does not heal when treated with calcium phosphate bone void fillers or cements alone. This is the first study to report settable autograft extenders with bone-like strength and handling properties comparable to ceramic bone cements, which have the potential to improve treatment of bone fractures and other orthopedic conditions.

Entities:  

Keywords:  autograft extender; bone; polyurethane; rabbit; thioketal

Mesh：

Substances：

Year:  2019        PMID： 30398387      PMCID： PMC6648232          DOI： 10.1089/ten.TEA.2018.0223

Source DB:  PubMed          Journal:  Tissue Eng Part A        ISSN： 1937-3341            Impact factor:   3.845


  67 in total

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Journal:  J Biomed Mater Res A       Date:  2009-09-01       Impact factor: 4.396

Review 4.  Key aspects on the use of bone substitutes for bone regeneration of edentulous ridges.

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Review 5.  Animal models for implant biomaterial research in bone: a review.

Authors:  A I Pearce; R G Richards; S Milz; E Schneider; S G Pearce
Journal:  Eur Cell Mater       Date:  2007-03-02       Impact factor: 3.942

6.  The fusion rate of calcium sulfate with local autograft bone compared with autologous iliac bone graft for instrumented short-segment spinal fusion.

Authors:  Wen-Jer Chen; Tsung-Ting Tsai; Lih-Huei Chen; Chi-Chien Niu; Po-Liang Lai; Tsai-Sheng Fu; Kevin McCarthy
Journal:  Spine (Phila Pa 1976)       Date:  2005-10-15       Impact factor: 3.468

7.  Compressive fatigue and fracture toughness behavior of injectable, settable bone cements.

Authors:  Andrew J Harmata; Sasidhar Uppuganti; Mathilde Granke; Scott A Guelcher; Jeffry S Nyman
Journal:  J Mech Behav Biomed Mater       Date:  2015-08-01

8.  A level-1 pilot study to evaluate of ultraporous beta-tricalcium phosphate as a graft extender in the posterior correction of adolescent idiopathic scoliosis.

Authors:  Thomas Lerner; Viola Bullmann; Tobias L Schulte; Marc Schneider; Ulf Liljenqvist
Journal:  Eur Spine J       Date:  2008-12-12       Impact factor: 3.134

9.  Porcine Ischemic Wound-Healing Model for Preclinical Testing of Degradable Biomaterials.

Authors:  Prarthana Patil; John R Martin; Samantha M Sarett; Alonda C Pollins; Nancy L Cardwell; Jeffrey M Davidson; Scott A Guelcher; Lillian B Nanney; Craig L Duvall
Journal:  Tissue Eng Part C Methods       Date:  2017-09-29       Impact factor: 3.056

10.  Injectable and compression-resistant low-viscosity polymer/ceramic composite carriers for rhBMP-2 in a rabbit model of posterolateral fusion: a pilot study.

Authors:  Stefanie M Shiels; Anne D Talley; Madison A P McGough; Katarzyna J Zienkiewicz; Kerem Kalpakci; Daniel Shimko; Scott A Guelcher; Joseph C Wenke
Journal:  J Orthop Surg Res       Date:  2017-07-11       Impact factor: 2.359
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  5 in total

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Journal:  Adv Healthc Mater       Date:  2021-03-18       Impact factor: 11.092

Review 2.  Applications of the ROS-Responsive Thioketal Linker for the Production of Smart Nanomedicines.

Authors:  Arianna Rinaldi; Riccardo Caraffi; Maria Vittoria Grazioli; Natalia Oddone; Luciana Giardino; Giovanni Tosi; Maria Angela Vandelli; Laura Calzà; Barbara Ruozi; Jason Thomas Duskey
Journal:  Polymers (Basel)       Date:  2022-02-11       Impact factor: 4.329

3.  Image-Based Evaluation of In Vivo Degradation for Shape-Memory Polymer Polyurethane Foam.

Authors:  Lance M Graul; Staci J Horn; Landon D Nash; Thomas B Cheung; Fred J Clubb; Duncan J Maitland
Journal:  Polymers (Basel)       Date:  2022-10-01       Impact factor: 4.967

4.  Effects of nanocrystalline hydroxyapatite concentration and skeletal site on bone and cartilage formation in rats.

Authors:  Lauren A Boller; Stefanie M Shiels; David C Florian; Sun H Peck; Jonathan G Schoenecker; Craig Duvall; Joseph C Wenke; Scott A Guelcher
Journal:  Acta Biomater       Date:  2021-06-12       Impact factor: 10.633

5.  Settable Polymeric Autograft Extenders in a Rabbit Radius Model of Bone Formation.

Authors:  Lauren A Boller; Madison A P McGough; Stefanie M Shiels; Craig L Duvall; Joseph C Wenke; Scott A Guelcher
Journal:  Materials (Basel)       Date:  2021-07-15       Impact factor: 3.623
  5 in total

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