Literature DB >> 30327576

A Bioinformatics Module for Use in an Introductory Biology Laboratory.

Adrienne Alaie1, Virginia Teller1, Wei-Gang Qiu1.   

Abstract

Since biomedical science has become increasingly data-intensive, acquisition of computational and quantitative skills by science students has become more important. For non-science students, an introduction to biomedical databases and their applications promotes the development of a scientifically literate population. Because typical college introductory biology laboratories do not include experiences of this type, we present a bioinformatics module that can easily be included in a 90-minute session of a biology course for both majors and non-majors. Students completing this computational, inquiry-based module observed the value of computer-assisted analysis. The module gave students an understanding of how to read files in a biological database (GenBank) and how to use a software tool (BLAST) to mine the database.

Entities:  

Keywords:  BLAST; Bioinformatics; active learning; inquiry-based learning; undergraduate

Year:  2012        PMID: 30327576      PMCID: PMC6186437          DOI: 10.1525/abt.2012.74.5.6

Source DB:  PubMed          Journal:  Am Biol Teach        ISSN: 0002-7685            Impact factor:   0.342


  9 in total

1.  Is bio2010 the right blueprint for the biology of the future?

Authors:  Donald Kennedy
Journal:  Cell Biol Educ       Date:  2003

2.  Evolving strategies for the incorporation of bioinformatics within the undergraduate cell biology curriculum.

Authors:  Jerry E Honts
Journal:  Cell Biol Educ       Date:  2003

3.  Public access for teaching genomics, proteomics, and bioinformatics.

Authors:  A Malcolm Campbell
Journal:  Cell Biol Educ       Date:  2003

4.  Basic local alignment search tool.

Authors:  S F Altschul; W Gish; W Miller; E W Myers; D J Lipman
Journal:  J Mol Biol       Date:  1990-10-05       Impact factor: 5.469

5.  Relational databases: a transparent framework for encouraging biology students to think informatically.

Authors:  Michael Rice; William Gladstone; Michael Weir
Journal:  Cell Biol Educ       Date:  2004

6.  Teaching systems biology: an active-learning approach.

Authors:  Anuj Kumar
Journal:  Cell Biol Educ       Date:  2005

7.  A molecular genetics laboratory course applying bioinformatics and cell biology in the context of original research.

Authors:  Cynthia J Brame; Wendy M Pruitt; Lucy C Robinson
Journal:  CBE Life Sci Educ       Date:  2008       Impact factor: 3.325

8.  Design and implementation of an interdepartmental bioinformatics program across life science curricula.

Authors:  Jennifer A Miskowski; David R Howard; Michael L Abler; Sandra K Grunwald
Journal:  Biochem Mol Biol Educ       Date:  2007-01       Impact factor: 1.160

9.  An inquiry into protein structure and genetic disease: introducing undergraduates to bioinformatics in a large introductory course.

Authors:  April E Bednarski; Sarah C R Elgin; Himadri B Pakrasi
Journal:  Cell Biol Educ       Date:  2005
  9 in total

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