Michiro Sasaki1, Mitsuhiro Tozaki2, Katsuya Maruyama3, Thomas Benkert4, Wakana Murakami5, Daisuke Yotsumoto6, Shunichi Oosako7, Yoshiaki Sagara2. 1. Department of Radiology, Sagara Perth Avenue Clinic, 26-13 Shinyashiki-cho, Kagoshima city, 892-0838, Kagoshima, Japan. chacha622@sagara.or.jp. 2. Department of Radiology, Sagara Hospital Affiliated Breast Center, 3-28 Tenokuchi-cho, Kagoshima city, 892-0845, Kagoshima, Japan. 3. MR Research & Collaboration Dpt. Diagnostic Imaging Business Area, Siemens Healthcare K.K, Erlangen, Germany. 4. Siemens Healthcare GmbH, Erlangen, Germany. 5. Department of Radiology, National Defense Medical College, 3-2 Namiki, Tokorozawa city, Saitama, 359-0042, Japan. 6. Department of Breast Surgery, Sagara Hospital, 3-31Matsubara-cho, Kagoshima city, 892-0833, Kagoshima, Japan. 7. Image Inspection Department, Sagara Perth Avenue Clinic, 26-13 Shinyashiki-cho, Kagoshima city, 892-0838, Kagoshima, Japan.
Abstract
PURPOSE: To evaluate the feasibility of proposed integrated slice-by-slice shimming (iShim) for whole-body diffusion weighted imaging (WB-DWI) in comparison to conventional 3D shim in patients with breast cancer. MATERIALS AND METHODS: Retrospective analysis of 116 consecutive patients (116 lesions) who underwent whole-body PET/MR using iShim (iShim group) were performed and compared with historical control of 103 patients (105 lesions) using 3D Shim (3D Shim group). RESULTS: As compared with dynamic contrast-enhanced (DCE) breast MRI, the apparent diffusion coefficient (ADC) value could not be determined for 15 (14%) of the 105 lesions of the 3D shim group and for 10 (9%) of the 116 lesions on iShim group. The intergroup difference failed to reach statistical significance (P = 0.1843). On the other hand, there was a significant difference in the frequencies of PET-positive and DWI-negative lesions between the 3D shim and iShim group (8.6% vs. 1.7%, respectively, P = 0.01942). CONCLUSION: In regard to detectability of breast cancers by DWI, iShim may allow improved detectability as compared to conventional 3D shim.
PURPOSE: To evaluate the feasibility of proposed integrated slice-by-slice shimming (iShim) for whole-body diffusion weighted imaging (WB-DWI) in comparison to conventional 3D shim in patients with breast cancer. MATERIALS AND METHODS: Retrospective analysis of 116 consecutive patients (116 lesions) who underwent whole-body PET/MR using iShim (iShim group) were performed and compared with historical control of 103 patients (105 lesions) using 3D Shim (3D Shim group). RESULTS: As compared with dynamic contrast-enhanced (DCE) breast MRI, the apparent diffusion coefficient (ADC) value could not be determined for 15 (14%) of the 105 lesions of the 3D shim group and for 10 (9%) of the 116 lesions on iShim group. The intergroup difference failed to reach statistical significance (P = 0.1843). On the other hand, there was a significant difference in the frequencies of PET-positive and DWI-negative lesions between the 3D shim and iShim group (8.6% vs. 1.7%, respectively, P = 0.01942). CONCLUSION: In regard to detectability of breast cancers by DWI, iShim may allow improved detectability as compared to conventional 3D shim.
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